Results 21 to 30 of about 2,450,636 (325)

Anti-HIV-1 ADCC and HIV-1 Env Can Be Partners in Reducing Latent HIV Reservoir

Frontiers in Immunology, 2021
BackgroundPersistence of HIV reservoir even in suppressive ART is the key obstacle in HIV-1 cure. We evaluated the ability of HIV-1 C Env to reactivate the latently infected resting memory CD4 cells and the ability of polyclonal HIV antibodies mediating ...
Poonam Suryawanshi, Poonam Suryawanshi, Rajani Bagul, Ashwini Shete, Madhuri Thakar   +4 more
doaj   +1 more source

Phage display selection of HIV specific conserved mimotopes with IgG from long-term non-progressors [PDF]

, 2005
Poster presentation Background The aim of this study is to identify conserved epitopes of HIV-1 neutralizing antibodies in polyclonal plasma from LTNP to finally derive vaccine candidates.
Antoni, Sascha, Dietrich, Ursula, Dittmar, Matthias, Humber, Michael, Rodes, Berta, Schreiber, Andreas, Soriano, Vicente   +6 more
core   +1 more source

HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells

Cell Reports, 2019
Summary: Mucosal immune responses to HIV-1 involve the recognition of the viral envelope glycoprotein (gp)160 by tissue-resident B cells and subsequent secretion of antibodies.
Cyril Planchais, Ayrin Kök, Alexia Kanyavuz, Valérie Lorin, Timothée Bruel, Florence Guivel-Benhassine, Tim Rollenske, Julie Prigent, Thierry Hieu, Thierry Prazuck, Laurent Lefrou, Hedda Wardemann, Olivier Schwartz, Jordan D. Dimitrov, Laurent Hocqueloux, Hugo Mouquet   +15 more
doaj   +1 more source

Detection of HIV-1 infection in dried blood spots from a 12-year-old ABO bedside test card [PDF]

, 1998
Background and Objectives: We tested dried blood from an ABO bedside test card which had been stored at room temperature for 12 years, to prove that a patient with HIV-1 infection had been infected by blood transfusion. Materials and Methods: Immunoblots
Eberle, J., Emminger, Ch., Gürtler, L., Mayer, G., Strobel, Erwin   +4 more
core   +1 more source

Bispecific Antibodies Against HIV [PDF]

Cell, 2016
Synergistic bispecific antibodies against HIV exhibit extraordinary potency and breadth of neutralization as promising candidates for treatment and prevention.
openaire   +2 more sources

Persistence of hepatitis A virus antibodies after primary immunization and response to revaccination in children and adolescents with perinatal HIV exposure

Revista Paulista de Pediatria, 2015
OBJECTIVE: To assess possible factors associated with the loss of antibodies to hepatitis A 7 years after the primary immunization in children of HIV-infected mothers and the response to revaccination in patients seronegative for hepatitis A.
Aída de Fátima Thomé Barbosa Gouvêa, Maria Isabel de Moraes Pinto, Maristela Miyamoto, Daisy Maria Machado, Silvana Duarte Pessoa, Fabiana Bononi do Carmo, Suênia Cordeiro de Vasconcelos Beltrão, Regina Célia de Menezes Succi   +7 more
doaj   +1 more source

Functional stability of HIV-1 envelope trimer affects accessibility to broadly neutralizing antibodies at its apex [PDF]

, 2017
The trimeric envelope glycoprotein spike (Env) of HIV-1 is the target of vaccine development to elicit broadly neutralizing antibodies (bnAbs). Env trimer instability and heterogeneity in principle make subunit interfaces inconsistent targets for the ...
Gift, Syna Kuriakose, Kim, Arthur S, Leaman, Daniel P, Zhang, Lei, Zwick, Michael B   +4 more
core   +2 more sources

HIV broadly neutralizing antibody targets [PDF]

Current Opinion in HIV and AIDS, 2015
To provide an update on neutralizing antibody targets in the context of the recent HIV-1 envelope trimer structure, describe new antibody isolation technologies, and discuss the implications of these data for HIV-1 prevention and therapy.Recent advances in B-cell technologies have dramatically expanded the number of antibodies isolated from HIV ...
Constantinos Kurt, Wibmer, Penny L, Moore, Lynn, Morris   +2 more
openaire   +2 more sources

A Rapid, Self-confirming Assay for HIV: Simultaneous Detection of Anti-HIV Antibodies and Viral RNA

Journal of AIDS and Clinical Research, 2016
Objective We developed a microfluidic system to simultaneously detect host anti-HIV antibodies and viral RNA in the same specimen in order to satisfy two important diagnostic criteria, especially within resource-limited settings.
Zongyuan Chen, Hui Zhu, D. Malamud, C. Barber, Yhombi Yvon Serge Ongagna, R. Yasmin, S. Modak, M. Janal, W. Abrams, R. Montagna   +9 more
semanticscholar   +1 more source

Promise and problems associated with the use of recombinant AAV for the delivery of anti-HIV antibodies

Molecular Therapy: Methods & Clinical Development, 2016
Attempts to elicit antibodies with potent neutralizing activity against a broad range of human immunodeficiency virus (HIV) isolates have so far proven unsuccessful.
S. Fuchs, R. Desrosiers
semanticscholar   +1 more source