Results 21 to 30 of about 1,212,195 (296)

Persistence of hepatitis A virus antibodies after primary immunization and response to revaccination in children and adolescents with perinatal HIV exposure

Revista Paulista de Pediatria, 2015
OBJECTIVE: To assess possible factors associated with the loss of antibodies to hepatitis A 7 years after the primary immunization in children of HIV-infected mothers and the response to revaccination in patients seronegative for hepatitis A.
Aída de Fátima Thomé Barbosa Gouvêa, Maria Isabel de Moraes Pinto, Maristela Miyamoto, Daisy Maria Machado, Silvana Duarte Pessoa, Fabiana Bononi do Carmo, Suênia Cordeiro de Vasconcelos Beltrão, Regina Célia de Menezes Succi   +7 more
doaj   +1 more source

Detection of HIV-1 infection in dried blood spots from a 12-year-old ABO bedside test card [PDF]

, 1998
Background and Objectives: We tested dried blood from an ABO bedside test card which had been stored at room temperature for 12 years, to prove that a patient with HIV-1 infection had been infected by blood transfusion. Materials and Methods: Immunoblots
Mayer, G., Eberle, J., G. Mayer, L. Gürtler, Emminger, Ch., Strobel, Erwin, J. Eberle, Gürtler, L., E. Strobel, Ch. Emminger   +9 more
core   +1 more source

Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection. [PDF]

PLoS Medicine, 2009
The antibody response to HIV-1 does not appear in the plasma until approximately 2-5 weeks after transmission, and neutralizing antibodies to autologous HIV-1 generally do not become detectable until 12 weeks or more after transmission.
Marc C Levesque, M Anthony Moody, Kwan-Ki Hwang, Dawn J Marshall, John F Whitesides, Joshua D Amos, Thaddeus C Gurley, Sallie Allgood, Benjamin B Haynes, Nathan A Vandergrift, Steven Plonk, Daniel C Parker, Myron S Cohen, Georgia D Tomaras, Paul A Goepfert, George M Shaw, Jörn E Schmitz, Joseph J Eron, Nicholas J Shaheen, Charles B Hicks, Hua-Xin Liao, Martin Markowitz, Garnett Kelsoe, David M Margolis, Barton F Haynes   +24 more
doaj   +1 more source

9G4+ antibodies isolated from HIV-infected patients neutralize HIV-1 and have distinct autoreactivity profiles. [PDF]

PLoS ONE, 2013
Potent HIV-1 specific broadly neutralizing antibodies (BNA) are uncommon in HIV infected individuals, and have proven hard to elicit by vaccination. Several, isolated monoclonal BNA are polyreactive and also recognize self-antigens, suggesting a breach ...
Danielle C Alcéna, James J Kobie, Denise A Kaminski, Alexander F Rosenberg, Jonelle L Mattiacio, Matthew Brewer, Stephen Dewhurst, Carrie Dykes, Xia Jin, Michael C Keefer, Ignacio Sanz   +10 more
doaj   +1 more source

Canonical Antibodies Adopt Distinct Binding Modes to Recognize Viral Glycan Shields. [PDF]

Adv Sci (Weinh)
Canonical Y‐shaped antibodies recognize viral glycan shields through adaptive Fab assembly states shaped by glycan organization and somatic hypermutation. Structural analyses ofbroadly neutralizing antibodies VRC35 and VRC36 across glycoproteins of HIV‐1, influenza, SARS‐CoV‐2, and Lassa viruses reveal distinct Fab assembly states, spanning monovalent,
Cheng J, Cale EM, Maghsoudi A, Sutton MS, Longo NS, Gillespie RA, Wang L, Kosik I, Chong S, Yasuhara A, Bylund T, Schön A, Tripathi P, Tsybovsky Y, Lei H, Morano NC, Lupatkin AB, Morton AJ, Lang ZC, Becker JE, Frascilla IR, Lee M, Li N, Liu C, Roark RS, Shen CH, Teng IT, Van Wazer DJ, Wang D, Wu L, Ahlsen G, Castro M, Du H, Ernandes MJ, Li T, Lin BC, Louder MK, McKee K, Merriam JS, O'Dell S, Ou L, Pletnev S, Prikryl D, Qiu Q, Rubin S, Sastry M, Schmidt SD, Shajahan A, Shiakolas AR, Srivatsan S, Zhang B, Zhou Q, Connors M, Gall JG, Guo Y, Huang RK, Huang Y, Koup RA, Lei QP, Mascola JR, Rawi R, Serebryannyy L, Shapiro L, Sheng Z, Ho DD, Wilson PC, Yewdell JW, Pierson TC, Kanekiyo M, Doria-Rose NA, Kwong PD, Zhou T.   +71 more
europepmc   +2 more sources

Evaluating the neutralizing antibody response to HIV-1 membrane proximal external regional; Implications for vaccine design [PDF]

, 2014
Includes bibliographical references.Inducing broadly neutralizing antibodies targeting the HIV-1 envelope is thought to be crucial for developing an effective vaccine.
Jacob, Rajesh Abraham
core   +1 more source

Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses.

PLoS Pathogens, 2016
Emerging data support a role for antibody Fc-mediated antiviral activity in vaccine efficacy and in the control of HIV-1 replication by broadly neutralizing antibodies.
Matthew Zirui Tay, Pinghuang Liu, LaTonya D Williams, Michael D McRaven, Sheetal Sawant, Thaddeus C Gurley, Thomas T Xu, S Moses Dennison, Hua-Xin Liao, Agnès-Laurence Chenine, S Munir Alam, M Anthony Moody, Thomas J Hope, Barton F Haynes, Georgia D Tomaras   +14 more
doaj   +1 more source

Bispecific Antibodies Against HIV [PDF]

Cell, 2016
Synergistic bispecific antibodies against HIV exhibit extraordinary potency and breadth of neutralization as promising candidates for treatment and prevention.
openaire   +2 more sources

Genetic and immunological characterization of new subtype G envelope expressing HIV-1 pseudoviruses [PDF]

, 2014
Includes bibliographical references.One of the greatest challenges for the development of an effective HIV-1 vaccine is the high genetic diversity of this pathogen and the complex escape mechanisms employed by the envelope gp120 and gp41 glycoprotein ...
Essomba, Rene Ghislain
core   +1 more source

Semen IgM, IgG1, and IgG3 Differentially Associate With Pro-Inflammatory Cytokines in HIV-Infected Men

Frontiers in Immunology, 2019
Genital inflammation significantly increases the risk for HIV infection. The seminal environment is enriched in pro-inflammatory cytokines and chemokines.
Thevani Pillay, Parveen Sobia, Abraham Jacobus Olivier, Kapil Narain, Lenine J. P. Liebenberg, Lenine J. P. Liebenberg, Sinaye Ngcapu, Sinaye Ngcapu, Mesuli Mhlongo, Jo-Ann S. Passmore, Jo-Ann S. Passmore, Jo-Ann S. Passmore, Jo-Ann S. Passmore, Cheryl Baxter, Derseree Archary, Derseree Archary   +15 more
doaj   +1 more source