Results 111 to 120 of about 314,387 (344)
The epidemiological impact of antiretroviral use predicted by mathematical models: a review [PDF]
, 2005 This review summarises theoretical studies attempting to assess the population impact of antiretroviral therapy (ART) use on mortality and HIV incidence.
Baggaley, Rebecca F +2 more
core +3 more sources
HIV drug resistance in HIV-infected children
Jornal de Pediatria, 2009 Almeida et al. report, in this issue of the journal, a retrospective studyon theprevalence and patterns of antiretroviral drug resistance in 24 treatment-naive and 23 treatment-experienced children failing therapy between 2000 and 2004 attending a clinic in Sao Paulo.
openaire +2 more sources
Antibody‐Empowered Nanomedicine for Precise Biomedical Applications
Advanced Science, EarlyView.This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen +7 more
wiley +1 more source
Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases
Advanced Science, EarlyView.This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo +5 more
wiley +1 more source
Туберкулез и болезни лёгких, 2017 Goal: to study the structure, profile of primary drug resistance and viability of mycobacteria in tuberculosis patients with concurrent HIV infection.Materials and methods.
N. M. Koretskaya, I. A. Bolshakova
doaj +1 more source
Genetic diversity and baseline drug resistance of South African HIV-1 Integrase sequences prior to the availability of Integrase strand-transfer inhibitors [PDF]
, 2020 Dominik Brado
openalex +1 more source
HIV-1 drug mutations in children from northern Tanzania [PDF]
, 2014 Objectives: In resource-limited settings, it is a challenge to get quality clinical specimens due to poor infrastructure for their collection, transportation, processing and storage. Using dried blood spots (DBS) might be an alternative to plasma for HIV-
Shao, Elichilia R. +9 more
core +2 more sources
Advanced Intelligent Discovery, EarlyView.This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng +4 more
wiley +1 more source
Advances in HIV-1 resistance detection technology
Guangxi Yike Daxue xuebaoHIV has ravaged the world for more than forty years, causing great pressure on global public health. Today, AIDS is still a medical challenge for global public health.
SHEN Kuiling +3 more
doaj +1 more source
Advanced Intelligent Discovery, EarlyView.This study integrates random matrix theory (RMT) and principal component analysis (PCA) to improve the identification of correlated regions in HIV protein sequences for vaccine design. PCA validation enhances the reliability of RMT‐derived correlations, particularly in small‐sample, high‐dimensional datasets, enabling more accurate detection of ...
Mariyam Siddiqah +3 more
wiley +1 more source