New England Journal of Medicine, 2004 To the Editor: Clavel and Hance (March 4 issue)1 review resistance to drugs used for the treatment of human immunodeficiency virus infection. Few data are available concerning patterns of antiretroviral-drug resistance among patients in developing countries.
Calmy, Alexandra +2 more
+6 more sources
BMJ, 2007 HIV has an impressive ability to replicate, mutate, and diversify, so developing drugs or vaccines that can fully contain the virus is a challenge. The only consistently successful way to prevent replication of HIV is to administer a potent combination regimen that contains at least two and preferably three antiretroviral drugs.
Hiroyu, Hatano, Steven G, Deeks
openaire +2 more sources
Using machine learning and big data to explore the drug resistance landscape in HIV.
PLoS Computational Biology, 2021 Drug resistance mutations (DRMs) appear in HIV under treatment pressure. DRMs are commonly transmitted to naive patients. The standard approach to reveal new DRMs is to test for significant frequency differences of mutations between treated and naive ...
Luc Blassel +6 more
doaj +1 more source
HIV and Drug-Resistant Subtypes
Microorganisms, 2023 Acquired Immunodeficiency Syndrome (AIDS) is a human viral infectious disease caused by the positive-sense single-stranded (ss) RNA Human Immunodeficiency Virus (HIV) (Retroviridae family, Ortervirales order). HIV-1 can be distinguished into various worldwide spread groups and subtypes.
Bianca Maria Nastri +7 more
openaire +3 more sources
Southern African Treatment Resistance Network (SATuRN) RegaDB HIV drug resistance and clinical management database: supporting patient management, surveillance and research in southern Africa [PDF]
, 2014 Substantial amounts of data have been generated from patient management and academic exercises designed to better understand the human immunodeficiency virus (HIV) epidemic and design interventions to control it.
Bester, Armand +17 more
core +3 more sources
Detecting Mutations in the Mycobacterium tuberculosis Pyrazinamidase Gene pncA to Improve Infection Control and Decrease Drug Resistance Rates in Human Immunodeficiency Virus Coinfection. [PDF]
, 2016 Hospital infection control measures are crucial to tuberculosis (TB) control strategies within settings caring for human immunodeficiency virus (HIV)-positive patients, as these patients are at heightened risk of developing TB.
Bangsberg +41 more
core +2 more sources
Application of high-throughput sequencing technology in HIV drug resistance detection
Biosafety and Health, 2021 Drug resistance via drug-resistant mutations in the human immunodeficiency virus (HIV) genome is the primary cause of antiviral therapy failure. Consequently, HIV drug resistance genotyping has become a critical approach in HIV prevention and control ...
Yuanyuan Zhang, Liying Ma
doaj +1 more source
The HIV-1 subtype C epidemic in South America is linked to the United Kingdom.
PLoS ONE, 2010 BackgroundThe global spread of HIV-1 has been accompanied by the emergence of genetically distinct viral strains. Over the past two decades subtype C viruses, which predominate in Southern and Eastern Africa, have spread rapidly throughout parts of South
Tulio de Oliveira +3 more
doaj +1 more source
Factors influencing the emergence and spread of HIV drug resistance arising from rollout of antiretroviral pre-exposure prophylaxis (PrEP). [PDF]
PLoS ONE, 2011 The potential for emergence and spread of HIV drug resistance from rollout of antiretroviral (ARV) pre-exposure prophylaxis (PrEP) is an important public health concern.
Ume L Abbas +3 more
doaj +1 more source