Results 21 to 30 of about 308,174 (298)

Predictors of poor retention on antiretroviral therapy as a major HIV drug resistance early warning indicator in Cameroon: results from a nationwide systematic random sampling

BMC Infectious Diseases, 2016
Background Retention on lifelong antiretroviral therapy (ART) is essential in sustaining treatment success while preventing HIV drug resistance (HIVDR), especially in resource-limited settings (RLS).
Serge Clotaire Billong, Joseph Fokam, Calixte Ida Penda, Salmon Amadou, David Same Kob, Edson-Joan Billong, Vittorio Colizzi, Alexis Ndjolo, Anne-Cecile Zoung-Kani Bisseck, Jean-Bosco Nfetam Elat   +9 more
doaj   +1 more source

Nucleic Acid, Antibody, and Virus Culture Methods to Detect Xenotropic MLV-Related Virus in Human Blood Samples

Advances in Virology, 2011
The MLV-related retrovirus, XMRV, was recently identified and reported to be associated with both prostate cancer and chronic fatigue syndrome. At the National Cancer Institute-Frederick, MD (NCI-Frederick), we developed highly sensitive methods to ...
M. F. Kearney, K. Lee, R. K. Bagni, A. Wiegand, J. Spindler, F. Maldarelli, P. A. Pinto, W. M. Linehan, C. D. Vocke, K. A. Delviks-Frankenberry, R. W. deVere White, G. Q. Del Prete, J. W. Mellors, J. D. Lifson, V. N. KewalRamani, V. K. Pathak, J. M. Coffin, S. F. J. Le Grice   +17 more
doaj   +1 more source

Differences in drug resistance of HIV-1 genotypes in CSF and plasma and analysis of related factors

Virulence, 2023
The emergence of HIV drug resistance seriously affects the quality of life of patients. However, there has been no extensive study of CSF resistance. The aim of this study is to evaluate common HIV-1 resistance in CSF and compare it with resistance in ...
Jie Wang, Mei Li, Jungang Li, Renni Deng
doaj   +1 more source

The HIV-1 subtype C epidemic in South America is linked to the United Kingdom.

PLoS ONE, 2010
BackgroundThe global spread of HIV-1 has been accompanied by the emergence of genetically distinct viral strains. Over the past two decades subtype C viruses, which predominate in Southern and Eastern Africa, have spread rapidly throughout parts of South
Tulio de Oliveira, Deenan Pillay, Robert J Gifford, UK Collaborative Group on HIV Drug Resistance   +3 more
doaj   +1 more source

Murine Leukemia Viruses: Objects and Organisms

Advances in Virology, 2011
Murine leukemia viruses (MLVs) are among the simplest retroviruses. Prototypical gammaretroviruses encode only the three polyproteins that will be used in the assembly of progeny virus particles.
Alan Rein
doaj   +1 more source

Prediction and molecular field view of drug resistance in HIV-1 protease mutants

Scientific Reports, 2022
Conquering the mutational drug resistance is a great challenge in anti-HIV drug development and therapy. Quantitatively predicting the mutational drug resistance in molecular level and elucidating the three dimensional structure-resistance relationships ...
Baifan Wang, Yinwu He, Xin Wen, Zhen Xi
doaj   +1 more source

Characterization of the patterns of drug-resistance mutations in newly diagnosed HIV-1 infected patients naïve to the antiretroviral drugs [PDF]

, 2009
Background: The transmission of HIV-1 drug-resistant strains in drug naive patients may seriously compromise the efficacy of a first-line antiretroviral treatment.
Claudia Alteri, Valentina Svicher, Caterina Gori, Roberta D'Arrigo, Massimo Ciccozzi, Francesca Ceccherini-Silberstein, Marina Selleri, Stefano Aviani Bardacci, Massimo Giuliani, Paola Elia, Paola Scognamiglio, Roberta Balzano, Nicoletta Orchi, Enrico Girardi, Carlo Federico Perno, D Pillay, V Tozzi, D Costagliola, AM Wensing, SJ Little, SJ Little, ML Chaix, O Peuchant, MS Hirsch, Department of Health and Human Services, RM Novak, AM Wensing, S Yerly, UK Collaborative Group on HIV Drug-resistance, UK Collaborative HIV Cohort Study, UKRegister of HIV Seroconverters, BA Payne, SPREAD programme, N Orchi, B Suligoi, M Selleri, B Suligoi, F Ceccherini-Silberstein, JD Thompson, TA Hall, T de Oliveira, KL Swafford, D Posada, S Ray, RW Shafer, RW Shafer, A Lindström, V Svicher, LT Bacheler, SM Blower, HS Weinstock, J Vingerhoets, A de Ronde, JG Garcia-Lerma, M Violin, C Alteri, MM Santoro   +54 more
core   +2 more sources

Epidemic Characteristics of HIV Drug Resistance in Hefei, Anhui Province

Pathogens, 2022
To study the characteristics of HIV pretreatment drug resistance (PDR) and acquired drug resistance (ADR) in Hefei, a cross-sectional survey was used to collect 816 samples from newly reported HIV infections from 2017 to 2020 and 127 samples from HIV ...
Shan Zheng, Jianjun Wu, Jingjing Hao, Dong Wang, Zhongwang Hu, Lei Liu, Chang Song, Jing Hu, Yanhua Lei, Hai Wang, Lingjie Liao, Yi Feng, Yiming Shao, Yuhua Ruan, Hui Xing   +14 more
doaj   +1 more source

The role of drug resistance in poor viral suppression in rural South Africa: findings from a population-based study. [PDF]

, 2020
BACKGROUND:Understanding factors driving virological failure, including the contribution of HIV drug resistance mutations (DRM), is critical to ensuring HIV treatment remains effective.
Barnhart, Scott, Gilmore, Hailey J, Grignon, Jessica S, Hunt, Gillian, Liegler, Teri, Lippman, Sheri A, Mooney, Alyssa C, Prach, Lisa M, Puren, Adrian, Truong, Hong-Ha M   +9 more
core  

Antiretroviral drug resistant HIV-1 in women and children living in Honduras [PDF]

, 2013
Antiretroviral therapy (ART) in HIV infected pregnant women contributes to the prevention of HIV transmission to the newborn. However, as ART can also induce HIV drug resistance during suboptimal levels of virological suppression a major concern is the ...
Parham, Leda
core   +1 more source