Results 31 to 40 of about 4,391,067 (296)
Access to art, adherence and drug resistance among HIV-Positive patients in rural Tanzania [PDF]
, 2015 HIV is one of the worst pandemics in recent times, having affected more than 70 million and with a mortality rate close to 50%. Antiretroviral drugs fight viral replication and has improved life of HIV infected patients since it was introduced.
Nyogea, Daniel, Nyogea, Daniel Simon
core +1 more source
Differences in drug resistance of HIV-1 genotypes in CSF and plasma and analysis of related factors
Virulence, 2023 The emergence of HIV drug resistance seriously affects the quality of life of patients. However, there has been no extensive study of CSF resistance. The aim of this study is to evaluate common HIV-1 resistance in CSF and compare it with resistance in ...
Jie Wang, Mei Li, Jungang Li, Renni Deng
doaj +1 more source
Evolution of drug resistance in HIV protease [PDF]
BMC Bioinformatics, 2020 AbstractBackgroundDrug resistance is a critical problem limiting effective antiviral therapy for HIV/AIDS. Computational techniques for predicting drug resistance profiles from genomic data can accelerate the appropriate choice of therapy. These techniques can also be used to identify protease mutants for experimental studies of resistance and thereby ...
Dhara Shah +3 more
openaire +3 more sources
HIV Drug Resistance (HIVDR) in Antiretroviral Therapy-Naïve Patients in Tanzania not Eligible for WHO Threshold HIVDR Survey is Dramatically High. [PDF]
, 2011 The World Health Organization (WHO) has recommended guidelines for a HIV drug resistance (HIVDR) survey for resource-limited countries. Eligibility criteria for patients include age below 25 years in order to focus on the prevalence of transmitted HIVDR (
Majinge, Charles +57 more
core +2 more sources
Murine Leukemia Viruses: Objects and Organisms
Advances in Virology, 2011 Murine leukemia viruses (MLVs) are among the simplest retroviruses. Prototypical gammaretroviruses encode only the three polyproteins that will be used in the assembly of progeny virus particles.
Alan Rein
doaj +1 more source
Prediction and molecular field view of drug resistance in HIV-1 protease mutants
Scientific Reports, 2022 Conquering the mutational drug resistance is a great challenge in anti-HIV drug development and therapy. Quantitatively predicting the mutational drug resistance in molecular level and elucidating the three dimensional structure-resistance relationships ...
Baifan Wang, Yinwu He, Xin Wen, Zhen Xi
doaj +1 more source
HIV-1 drug-resistance and drug-dependence [PDF]
Retrovirology, 2007 In this review, we will describe several recent HIV-1 studies in which a drug-dependent virus variant was selected. A common evolutionary route to the drug-dependence phenotype is proposed. First, the selection of a drug-resistance mutation that also affects the function of the targeted viral protein.
Baldwin, Chris, Berkhout, Ben
openaire +3 more sources
Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients
Advances in Virology, 2011 Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with human prostate cancer and chronic fatigue syndrome. Since retroviruses cause various cancers, and XMRV replication might be facilitated by HIV-1 co-
Krista A. Delviks-Frankenberry +5 more
doaj +1 more source
International Journal of Infectious Diseases, 2018 Objective: The objective of this review was to assess the burden of HIV drug resistance mutations (DRM) in Indian adults exposed to first-line antiretroviral therapy (ART) as per national guidelines.
Santosh Karade +6 more
doaj +1 more source
Tropical Medicine and Infectious Disease, 2021 The increase in HIV infection and drug-resistant strains is an important public health concern, especially in resource-limited settings. However, the identification of factors related to the propagation of infectious diseases represents a crucial target ...
Cruz S. Sebastião +2 more
doaj +1 more source