Results 11 to 20 of about 308,174 (298)

Using machine learning and big data to explore the drug resistance landscape in HIV.

PLoS Computational Biology, 2021
Drug resistance mutations (DRMs) appear in HIV under treatment pressure. DRMs are commonly transmitted to naive patients. The standard approach to reveal new DRMs is to test for significant frequency differences of mutations between treated and naive ...
Luc Blassel, Anna Tostevin, Christian Julian Villabona-Arenas, Martine Peeters, Stéphane Hué, Olivier Gascuel, UK HIV Drug Resistance Database   +6 more
doaj   +1 more source

Analysis of prevalence of HIV-1 drug resistance in primary infections in the United Kingdom [PDF]

, 2001
Objectives: To identify changes since 1994 in the prevalence of resistance to anti-HIV drugs in primary HIV-1 infections in the United Kingdom. Design: Retrospective and prospective assessment of viruses obtained from people recently infected with HIV.
Baily, Guy, Cane, Patricia, Churchill, Duncan, Dean, Gill, Drake, Susan, Fisher, Martin, Pillay, Deenan, Porter, Kholoud   +7 more
core   +2 more sources

HIV and Drug-Resistant Subtypes

Microorganisms, 2023
Acquired Immunodeficiency Syndrome (AIDS) is a human viral infectious disease caused by the positive-sense single-stranded (ss) RNA Human Immunodeficiency Virus (HIV) (Retroviridae family, Ortervirales order). HIV-1 can be distinguished into various worldwide spread groups and subtypes.
Bianca Maria Nastri, Pasquale Pagliano, Carla Zannella, Veronica Folliero, Alfonso Masullo, Luca Rinaldi, Massimiliano Galdiero, Gianluigi Franci   +7 more
openaire   +3 more sources

Southern African Treatment Resistance Network (SATuRN) RegaDB HIV drug resistance and clinical management database: supporting patient management, surveillance and research in southern Africa [PDF]

, 2014
Substantial amounts of data have been generated from patient management and academic exercises designed to better understand the human immunodeficiency virus (HIV) epidemic and design interventions to control it.
Bester, Armand, Chetty, Terusha, Danaviah, Siva, De Oliveira, Tulio, Goedhals, Dominique, Iwuji, Collins, Lessells, Richard, Manasa, Justen, McGrath, Nuala, Moodley, Pravi, Naidu, Kevindra, Rossouw, Theresa, Seebregts, Christopher J, Singh, Lavanya, Skingsley, Andrew, Stott, Katharine, Van Vuuren, Cloete, Van Zyl, Gert   +17 more
core   +3 more sources

Detecting Mutations in the Mycobacterium tuberculosis Pyrazinamidase Gene pncA to Improve Infection Control and Decrease Drug Resistance Rates in Human Immunodeficiency Virus Coinfection. [PDF]

, 2016
Hospital infection control measures are crucial to tuberculosis (TB) control strategies within settings caring for human immunodeficiency virus (HIV)-positive patients, as these patients are at heightened risk of developing TB.
Bangsberg, Butler, Campos, Carlton A. Evans, Caviedes, Daniela E. Kirwan, David A. J. Moore, Dooley, Eduardo Ticona, Escombe, Escombe, Evans, Franzblau, Hannan, Hu, Huang, Iwamoto, Jon S. Friedland, Jorge Coronel, Kawai, Lilia Z. Cabrera, Louis Grandjean, Luz Caviedes, Luz Huaroto, Matthew Z. Dudley, Mirko Zimic, Mitchison, Moore, Moore, Patricia Sheen, Raviglione, Richard Rodriguez, Robert H. Gilman, Scorpio, Sheen, Sheen, Sheen, Steele, Stricof, Víctor Chávez-Pérez, Wells, Willingham   +41 more
core   +2 more sources

HIV drug resistance in the era of contemporary antiretroviral therapy: A clinical perspective

Antiviral Therapy, 2023
Contemporary antiretroviral therapy (ART) regimens have high barriers to the development of drug resistance. However, resistance to earlier antiretrovirals and uncommon cases of resistance to contemporary ART illustrate the continued need for good ...
Andrew Carr, Nicola E Mackie, Roger Paredes, Kiat Ruxrungtham   +3 more
doaj   +1 more source

Application of high-throughput sequencing technology in HIV drug resistance detection

Biosafety and Health, 2021
Drug resistance via drug-resistant mutations in the human immunodeficiency virus (HIV) genome is the primary cause of antiviral therapy failure. Consequently, HIV drug resistance genotyping has become a critical approach in HIV prevention and control ...
Yuanyuan Zhang, Liying Ma
doaj   +1 more source

Antiretroviral drug resistance mutations in naïve and experienced patients in Shiraz, Iran, 2014 [PDF]

, 2016
Resistance to antiretroviral agents is a significant concern in the clinical management of HIV-infected individuals, particularly in areas of the world where treatment options are limited.
Aghasadeghi, M.R., Baesi, K., Davarpanah, M.A., McFarland, W., Moradi, A., Naziri, H., Tabarraei, A.   +6 more
core   +1 more source

The declining trend of HIV-Infection among pregnant women in Cameroon infers an epidemic decline in the general population

Heliyon, 2020
Background: HIV remains a generalised epidemic in Cameroon, with regular sentinel surveillance surveys (SSS) conducted among pregnant women to monitor the epidemiological dynamics, and for strategic policy making. Our main objective was to actualise data
Serge-Clotaire Billong, Joseph Fokam, Jean de Dieu Anoubissi, Cyprien Kengne Nde, Raoul Toukam Fodjo, Marinette Ngo Nemb, Yasmine Moussa, Arlette Lienou Messeh, Alexis Ndjolo, Jean-Bosco Nfetam Elat   +9 more
doaj   +1 more source

Factors influencing the emergence and spread of HIV drug resistance arising from rollout of antiretroviral pre-exposure prophylaxis (PrEP). [PDF]

PLoS ONE, 2011
The potential for emergence and spread of HIV drug resistance from rollout of antiretroviral (ARV) pre-exposure prophylaxis (PrEP) is an important public health concern.
Ume L Abbas, Gregory Hood, Arthur W Wetzel, John W Mellors   +3 more
doaj   +1 more source