Results 191 to 200 of about 314,387 (344)

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

Network Dynamics and Evolutionary Drivers of HIV Drug Resistance in Eastern China, from 2022 to 2024. [PDF]

Viruses
Cao D, Xing H, Feng Y, Zhang J, Zhou L, Jiang Z, Chen J, He T.   +7 more
europepmc   +1 more source

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

Phytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam, Abdur Rauf, Happy Akter, Md. Ibrahim Khalil Al‐Imran, Md. Naeem Hossain Fakir, Gazi Kaifeara Thufa, Umme Habiba, Karjin Nahar Riya, Md. Mahfuzur Rahman, Md Sadique Hussain, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Dorota Formanowicz, Marcello Iriti   +14 more
wiley   +1 more source

Surveillance of HIV-1 pol transmitted drug resistance in acutely and recently infected antiretroviral drug-naïve persons in rural western Kenya

, 2017
Harris Onywera, David Maman, Seth Inzaule, Erick Auma, Kennedy Were, Harrison Fredrick, Prestone Owiti, Valarie Opollo, Jean-François Étard, Irene Mukui, Andrea A. Kim, Clement Zeh   +11 more
openalex   +2 more sources

HIV diversity and drug resistance from plasma and non‐plasma analytes in a large treatment programme in western Kenya [PDF]

, 2014
Rami Kantor, Allison DeLong, Maya Balamane, Leeann Schreier, Robert M. Lloyd, Wilfred Emonyi, Lydia Kamle, Fidelis Mambo, Sarah Muyonga, David Katzenstein, Joseph W. Hogan, Nathan Buziba, Lameck Diero   +12 more
openalex   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Pre-treatment and acquired HIV drug resistance in Hunan: a cross-sectional analysis of a growing challenge. [PDF]

BMC Infect Dis
Long S, Yao R, Tang Y, Yu C, Tang W, Cao J, Huang Y, Lu X, Li S, Liu R, Dai L, Huang Y, Zheng F.   +12 more
europepmc   +1 more source

HIV Drug Resistance Early Warning Indicators in Namibia with Updated World Health Organization Guidance

, 2014
Anna Jonas, Victor Sumbi, Samson Mwinga, Michael DeKlerk, Francina Tjituka, Scott W. Penney, Michael R. Jordan, Desta Alamerew Tiruneh, Alice Tang, Steven Y. Hong   +9 more
openalex   +2 more sources

Evidence Suggests Prophylactic Antibiotics May Be Unnecessary in Anorectal Surgery—A Systematic Review and Meta‐Analysis

World Journal of Surgery, EarlyView.
Current evidence does not support the routine use of prophylactic antibiotics in uncomplicated anorectal procedures. However, the certainty of evidence is limited by small sample sizes, methodological heterogeneity, and limited number of available studies. Large‐scale randomized trials are required to strengthen this evidence base.
James Jin, Velia Men, Maggie Wang, Andrew Hill   +3 more
wiley   +1 more source

HIV Type-1 Transmission Dynamics in Recent Seroconverters: Relationship with Transmission of drug Resistance and Viral Diversity [PDF]

, 2008
Patrícia Recordon-Pinson, Guerric Anies, Mathias Bruyand, D. Neau, Philippe Morlat, Jean‐Luc Pellegrin, Alexis Groppi, Rodolphe Thiébaut, François Dabis, Hervé Fleury, Bernard Masquelier, the ANRS CO3 Aquitaine Cohort   +11 more
openalex   +1 more source