Results 21 to 30 of about 314,387 (344)

Analysis of prevalence of HIV-1 drug resistance in primary infections in the United Kingdom [PDF]

, 2001
Objectives: To identify changes since 1994 in the prevalence of resistance to anti-HIV drugs in primary HIV-1 infections in the United Kingdom. Design: Retrospective and prospective assessment of viruses obtained from people recently infected with HIV.
Baily, Guy, Cane, Patricia, Churchill, Duncan, Dean, Gill, Drake, Susan, Fisher, Martin, Pillay, Deenan, Porter, Kholoud   +7 more
core   +2 more sources

The declining trend of HIV-Infection among pregnant women in Cameroon infers an epidemic decline in the general population

Heliyon, 2020
Background: HIV remains a generalised epidemic in Cameroon, with regular sentinel surveillance surveys (SSS) conducted among pregnant women to monitor the epidemiological dynamics, and for strategic policy making. Our main objective was to actualise data
Serge-Clotaire Billong, Joseph Fokam, Jean de Dieu Anoubissi, Cyprien Kengne Nde, Raoul Toukam Fodjo, Marinette Ngo Nemb, Yasmine Moussa, Arlette Lienou Messeh, Alexis Ndjolo, Jean-Bosco Nfetam Elat   +9 more
doaj   +1 more source

Predictors of poor retention on antiretroviral therapy as a major HIV drug resistance early warning indicator in Cameroon: results from a nationwide systematic random sampling

BMC Infectious Diseases, 2016
Background Retention on lifelong antiretroviral therapy (ART) is essential in sustaining treatment success while preventing HIV drug resistance (HIVDR), especially in resource-limited settings (RLS).
Serge Clotaire Billong, Joseph Fokam, Calixte Ida Penda, Salmon Amadou, David Same Kob, Edson-Joan Billong, Vittorio Colizzi, Alexis Ndjolo, Anne-Cecile Zoung-Kani Bisseck, Jean-Bosco Nfetam Elat   +9 more
doaj   +1 more source

Nucleic Acid, Antibody, and Virus Culture Methods to Detect Xenotropic MLV-Related Virus in Human Blood Samples

Advances in Virology, 2011
The MLV-related retrovirus, XMRV, was recently identified and reported to be associated with both prostate cancer and chronic fatigue syndrome. At the National Cancer Institute-Frederick, MD (NCI-Frederick), we developed highly sensitive methods to ...
M. F. Kearney, K. Lee, R. K. Bagni, A. Wiegand, J. Spindler, F. Maldarelli, P. A. Pinto, W. M. Linehan, C. D. Vocke, K. A. Delviks-Frankenberry, R. W. deVere White, G. Q. Del Prete, J. W. Mellors, J. D. Lifson, V. N. KewalRamani, V. K. Pathak, J. M. Coffin, S. F. J. Le Grice   +17 more
doaj   +1 more source

Antiretroviral drug resistance mutations in naïve and experienced patients in Shiraz, Iran, 2014 [PDF]

, 2016
Resistance to antiretroviral agents is a significant concern in the clinical management of HIV-infected individuals, particularly in areas of the world where treatment options are limited.
Aghasadeghi, M.R., Baesi, K., Davarpanah, M.A., McFarland, W., Moradi, A., Naziri, H., Tabarraei, A.   +6 more
core   +1 more source

Differences in drug resistance of HIV-1 genotypes in CSF and plasma and analysis of related factors

Virulence, 2023
The emergence of HIV drug resistance seriously affects the quality of life of patients. However, there has been no extensive study of CSF resistance. The aim of this study is to evaluate common HIV-1 resistance in CSF and compare it with resistance in ...
Jie Wang, Mei Li, Jungang Li, Renni Deng
doaj   +1 more source

Prediction and molecular field view of drug resistance in HIV-1 protease mutants

Scientific Reports, 2022
Conquering the mutational drug resistance is a great challenge in anti-HIV drug development and therapy. Quantitatively predicting the mutational drug resistance in molecular level and elucidating the three dimensional structure-resistance relationships ...
Baifan Wang, Yinwu He, Xin Wen, Zhen Xi
doaj   +1 more source

Murine Leukemia Viruses: Objects and Organisms

Advances in Virology, 2011
Murine leukemia viruses (MLVs) are among the simplest retroviruses. Prototypical gammaretroviruses encode only the three polyproteins that will be used in the assembly of progeny virus particles.
Alan Rein
doaj   +1 more source

Epidemic Characteristics of HIV Drug Resistance in Hefei, Anhui Province

Pathogens, 2022
To study the characteristics of HIV pretreatment drug resistance (PDR) and acquired drug resistance (ADR) in Hefei, a cross-sectional survey was used to collect 816 samples from newly reported HIV infections from 2017 to 2020 and 127 samples from HIV ...
Shan Zheng, Jianjun Wu, Jingjing Hao, Dong Wang, Zhongwang Hu, Lei Liu, Chang Song, Jing Hu, Yanhua Lei, Hai Wang, Lingjie Liao, Yi Feng, Yiming Shao, Yuhua Ruan, Hui Xing   +14 more
doaj   +1 more source

In Vivo validation of a bioinformatics based tool to identify reduced replication capacity in HIV-1. [PDF]

, 2010
Although antiretroviral drug resistance is common in treated HIV infected individuals, it is not a consistent indicator of HIV morbidity and mortality.
Kitchen, Christina MR, Kitchen, Scott G, Krogstad, Paul   +2 more
core   +2 more sources