Results 41 to 50 of about 314,387 (344)

HIV-1 drug resistance and resistance testing [PDF]

Infection, Genetics and Evolution, 2016
The global scale-up of antiretroviral (ARV) therapy (ART) has led to dramatic reductions in HIV-1 mortality and incidence. However, HIV drug resistance (HIVDR) poses a potential threat to the long-term success of ART and is emerging as a threat to the elimination of AIDS as a public health problem by 2030.
Dana S. Clutter, Michael R. Jordan, Silvia Bertagnolio, Robert W. Shafer   +3 more
openaire   +2 more sources

Antiretroviral drug use and HIV drug resistance in female sex workers in Tanzania and the Dominican Republic.

PLoS ONE, 2020
ObjectiveFemale sex workers (FSW) have increased risk of HIV infection. Antiretroviral treatment (ART) can improve HIV outcomes and prevent HIV transmission.
Wendy Grant-McAuley, Jessica M Fogel, Noya Galai, William Clarke, Autumn Breaud, Mark A Marzinke, Jessie Mbwambo, Samuel Likindikoki, Said Aboud, Yeycy Donastorg, Martha Perez, Clare Barrington, Wendy Davis, Deanna Kerrigan, Susan H Eshleman   +14 more
doaj   +1 more source

Analysis of HIV-1 subtypes and drug resistance mutations in people who inject drugs in Aizawl and nearby districts of Mizoram, India

Virulence
Over the last decade, there has been a steady increase in HIV-1 prevalence in Mizoram, India. Importantly, this increase in HIV-1 prevalence is not only limited to the key population groups such as female sex workers (FSWs) or people who inject drugs ...
Komal Raskar, Lal Thlengliani, Andrew Lalbiaknunga, Dipali Kale, Ajit Patil, Pragati Chavan, Richard CLR Hluna, Samiran Panda, Swarali Kurle   +8 more
doaj   +1 more source

Prevalence of XMRV Nucleic Acid and Antibody in HIV-1-Infected Men and in Men at Risk for HIV-1 Infection

Advances in Virology, 2011
Xenotropic MLV-Related Virus (XMRV) was recently reported to be associated with prostate cancer and chronic fatigue syndrome (CFS). Infection was also reported in 3.7% of healthy individuals.
J. Spindler, J. Hackett, X. Qiu, A. Wiegand, V. F. Boltz, P. Swanson, J. H. Bream, L. P. Jacobson, X. Li, C. R. Rinaldo, S. M. Wolinsky, J. M. Coffin, M. F. Kearney, J. W. Mellors   +13 more
doaj   +1 more source

Drug resistance and drug resistance gene analysis for 205 cases of pulmonary tuberculosis with HIV-infected patients

Pifu-xingbing zhenliaoxue zazhi, 2022
Objective To investigate the drug resistance and drug resistance genes in human immunodeficiency virus (HIV) -infected patients with pulmonary tuberculosis (TB) in Zhengzhou, Henan province, so as to provide reference for effective diagnosis and ...
Ge LI, Zhongfeng CUI, Xiaojiu CAO
doaj   +1 more source

High Levels of Transmitted HIV Drug Resistance in a Study in Papua New Guinea.

PLoS ONE, 2017
IntroductionPapua New Guinea is a Pacific Island nation of 7.3 million people with an estimated HIV prevalence of 0.8%. ART initiation and monitoring are guided by clinical staging and CD4 cell counts, when available.
Evelyn Lavu, Ellan Kave, Euodia Mosoro, Jessica Markby, Eman Aleksic, Janet Gare, Imogen A Elsum, Gideon Nano, Petronia Kaima, Nick Dala, Anup Gurung, Silvia Bertagnolio, Suzanne M Crowe, Mark Myatt, Anna C Hearps, Michael R Jordan   +15 more
doaj   +1 more source

HIV-1 drug-resistance surveillance among treatment-experienced and -naïve patients after the implementation of antiretroviral therapy in Ghana. [PDF]

PLoS ONE, 2013
BACKGROUND: Limited HIV-1 drug-resistance surveillance has been carried out in Ghana since the implementation of antiretroviral therapy (ART). This study sought to provide data on the profile of HIV-1 drug resistance in ART-experienced and newly ...
Nicholas I Nii-Trebi, Shiro Ibe, Jacob S Barnor, Koichi Ishikawa, James A M Brandful, Sampson B Ofori, Shoji Yamaoka, William K Ampofo, Wataru Sugiura   +8 more
doaj   +1 more source

Antiretroviral recommendations may influence the rate of transmission of drug-resistant HIV type 1 [PDF]

, 2005
Producción CientíficaHuman immunodeficiency virus (HIV) treatment guidelines have evolved, shifting from more-aggressive to more-conservative approaches. The potential impact of these shifts on the transmission of drug-resistant virus is unknown.
Aguero, Jesús, Alcacer García, Federico, Colomina, Javier, Corral, Angélica, Eiros Bouza, José María, Leiva, Pilar, Mendoza, Carmen de, Ortiz de Lejarazu Leonardo, Raúl, Pedreira, José, Rodríguez, Carmen, Romero, Jorge del, Soriano, Vincent, Torre Cisneros, Julián, Viciana Ramos, María Isabel   +13 more
core   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

HIV Drug Resistance

Journal of Human Virology & Retrovirology, 2016
Submit Manuscript | http://medcraveonline.com with nonnucleoside reverse inhibitors (NNRTIs). Pre-therapy resistance is associated with first-line therapy failure. The most common viral mutations in HIV/AIDS patients with ARV drug resistance are M184/V, K103N, and M230L.
openaire   +2 more sources