Results 11 to 20 of about 937,893 (307)

HIV infection [PDF]

open access: yesNature Reviews Disease Primers, 2015
More than 75 million people worldwide have been infected with human immunodeficiency virus (HIV), and there are now approximately 37 million individuals living with the infection. Untreated HIV replication causes progressive CD4(+) T cell loss and a wide range of immunological abnormalities, leading to an increased risk of infectious and oncological ...
Steven G, Deeks   +3 more
openaire   +5 more sources

Durable natural killer cell response after three doses of SARS-CoV-2 inactivated vaccine in HIV-infected individuals

open access: yesChinese Medical Journal, 2023
. Background:. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine can induce a potent cellular and humoral immune response to protect against SARS-CoV-2 infection.
Xiaodong Yang   +14 more
doaj   +1 more source

Breast Milk from Tanzanian Women has Divergent Effects on Cell-Free and Cell-Associated HIV-1 Infection in Vitro. [PDF]

open access: yes, 2012
Transmission of HIV-1 during breastfeeding is a significant source of new pediatric infections in sub-Saharan Africa. Breast milk from HIV-positive mothers contains both cell-free and cell-associated virus; however, the impact of breast milk on HIV-1 ...
Alexandra L. Howell   +7 more
core   +9 more sources

PrEP use and unmet PrEP-need among men who have sex with men in London prior to the implementation of a national PrEP programme, a cross-sectional study from June to August 2019

open access: yesBMC Public Health, 2022
Background Access to prevention options, including HIV pre-exposure prophylaxis (PrEP), remains a public health priority for gay, bisexual, and other men who have sex with men (MSM), especially in London. We describe PrEP use in a London community sample
Dana Ogaz   +12 more
doaj   +1 more source

Relationship between levels of inflammatory cytokines in the genital tract and CD4+ cell counts in women with acute HIV-1 infection. [PDF]

open access: yes, 2008
Inflammatory responses at mucosal surfaces after human immunodeficiency virus type 1 (HIV-1) transmission may influence disease outcome. We evaluated levels of interleukin (IL)-1beta, IL-6, tumor necrosis factor-alpha, IL-8, IL-10, and IL-12 in genital ...
Bebell, Lisa M   +7 more
core   +1 more source

Service evaluation of an educational intervention to improve sexual health services in primary care implemented using a step-wedge design: analysis of chlamydia testing and diagnosis rate changes

open access: yesBMC Public Health, 2016
Background Providing sexual health services in primary care is an essential step towards universal provision. However they are not offered consistently. We conducted a national pilot of an educational intervention to improve staff’s skills and confidence
Katy Town   +7 more
doaj   +1 more source

Stem-cell-based gene therapy for HIV infection. [PDF]

open access: yes, 2013
Despite the enormous success of combined anti-retroviral therapy, HIV infection is still a lifelong disease and continues to spread rapidly worldwide. There is a pressing need to develop a treatment that will cure HIV infection.
Kitchen, Scott, Zhen, Anjie
core   +2 more sources

Clinically significant depressive symptoms and sexual behaviour among men who have sex with men

open access: yesBJPsych Open, 2017
Background The relationship between depression and sexual behaviour among men who have sex with men (MSM) is poorly understood.
Ada R. Miltz   +13 more
doaj   +1 more source

Vasculitides in HIV Infection [PDF]

open access: yesCurrent Rheumatology Reports, 2020
To review the spectrum of vasculitides in HIV-infected patients and to identify the clinical features that characterize vasculitis in sero-positive HIV.Epidemiological studies conducted in the post-HAART era described the rarity of vasculitis in the setting of HIV-infected patients. A study identified histopathological features such as leukocytoclastic
Vega, Luis E., Espinoza, Luis R.
openaire   +2 more sources

Primary HIV-1 Infection Among Infants in sub-Saharan Africa: HPTN 024. [PDF]

open access: yes, 2009
Our objectives were to assess clinical signs and diagnoses associated with primary HIV-1 infection among infants. We analyzed data from a clinical trial (HIV Prevention Trials Network Protocol 024) in sub-Saharan Africa.
Anthony Mwatha   +26 more
core   +2 more sources

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