Results 141 to 150 of about 26,857 (227)

Probing the Importance of the G-Quadruplex Grooves for the Activity of the Anti-HIV-Integrase Aptamer T30923. [PDF]

Int J Mol Sci, 2020
Esposito V, Esposito F, Pepe A, Gomez Monterrey I, Tramontano E, Mayol L, Virgilio A, Galeone A.   +7 more
europepmc   +1 more source

Structural basis of second-generation HIV integrase inhibitor action and viral resistance. [PDF]

Science, 2020
Cook NJ, Li W, Berta D, Badaoui M, Ballandras-Colas A, Nans A, Kotecha A, Rosta E, Engelman AN, Cherepanov P.   +9 more
europepmc   +1 more source

Characterization of HIV-1 Integrase Reactions with Viral DNA

, 2013
HIV-1 integrase (integrase) catalyzes the insertion of viral DNA into human chromosomes and is a focus for development of anti-integrase inhibitors to combat HIV infection. Integrase catalyzes two steps, a DNA-end cleavage reaction (3’-processing), and a
Kettlewell, Joanna
core  

Temporal Evolution of Drug Resistance to HIV Integrase Inhibitors. [PDF]

Viruses
Choudhuri I, Olvera JG, Biswas A, Haldane A, Levy RM, Lyumkis D.   +5 more
europepmc   +1 more source

Update on Adverse Effects of HIV Integrase Inhibitors. [PDF]

Curr Treat Options Infect Dis, 2019
Kolakowska A, Maresca AF, Collins IJ, Cailhol J.   +3 more
europepmc   +1 more source

HIV Integrase Inhibitor [PDF]

, 2020
openaire   +1 more source

Multifaceted HIV integrase functionalities and therapeutic strategies for their inhibition. [PDF]

J Biol Chem, 2019
Engelman AN.
europepmc   +1 more source

Development and Validation of a Machine Learning Model for Identifying Novel HIV Integrase Inhibitors. [PDF]

Cureus
Mukuhlani BT.
europepmc   +1 more source

Analysis of raltegravir analogs to enhance inhibitory efficiency against HIV integrase. [PDF]

Sci Rep
Sabaghian H, Yoosefian M.
europepmc   +1 more source

HIV Integrase Inhibitors for Treatment of HIV Infections and AIDS [PDF]

ACS Medicinal Chemistry Letters, 2014
openaire   +2 more sources