Results 131 to 140 of about 26,857 (227)
4-Hydroxy-5-pyrrolinone-3-carboxamide HIV-1 integrase inhibitors
, 2008 The viral enzyme integrase is essential for the replication of HIV-1 and, after the discovery of IsentressTM, represents a validated target for anti-retroviral therapy.
Pace +4 more
core +1 more source
Potential benefit of dolutegravir once daily: efficacy and safety
HIV/AIDS: Research and Palliative Care, 2013 Alessandra Fantauzzi,1 Ombretta Turriziani,2 Ivano Mezzaroma11Department of Clinical Medicine, 2Department of Molecular Medicine, Sapienza, University of Rome, Rome, ItalyAbstract: The viral integrase enzyme has recently emerged as a primary alternative ...
Fantauzzi A, Turriziani O, Mezzaroma I
doaj
Structural Biology of HIV Integrase Strand Transfer Inhibitors. [PDF]
Trends Pharmacol Sci, 2020 Jóźwik IK, Passos DO, Lyumkis D.
europepmc +1 more source
HIV integrase inhibitory activity of Agastache rugosa
, 1999 We have been screening anti-HIV integrase compounds from Korean medicinal plants by using an in vitro assay system which is mainly composed of recombinant human immunodeficency virus type 1 integrase and radiolabeled oligonucleotides.
Hye Kyong Kim +3 more
core +1 more source
Influence of the amino-terminal sequence on the structure and function of HIV integrase. [PDF]
Retrovirology, 2020 Eilers G +7 more
europepmc +1 more source
Characterization and structural analysis of HIV-1 integrase conservation
, 2009 The HIV-1 integrase, responsible for the chromosomal integration of the newly synthesized double-stranded viral DNA into the host genomic DNA, represents a new and important target of potential clinical relevance.
Perno, CF +7 more
core
Caffeoylquinic acids as inhibitors for HIV-I protease and HIV-I integrase: a molecular docking study [PDF]
, 2016 Caffeoylquinic acids are ubiquitous phenolic compounds with several health benefits to humans and they have been shown to be promisinganti-HIV compounds.
Castilho, Paula C. +2 more
core
Biochemical activity of RAGs is impeded by Dolutegravir, an HIV integrase inhibitor. [PDF]
Cell Death Discov, 2020 Nilavar NM, Paranjape AM, Raghavan SC.
europepmc +1 more source