Results 91 to 100 of about 71,892 (273)
Synthesis of New Potential HIV-1 Integrase Inhibitors [PDF]
HETEROCYCLES, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
FERRO, Stefania +7 more
openaire +6 more sources
Rethinking HIV treatment: How non‐integrase strand regimens may hold the key to better immune health
HIV Medicine, EarlyView.Abstract Purpose HIV outcome changed drastically with antiretroviral (ARV) therapy, especially after the introduction of second‐generation integrase strand transfer inhibitors (INSTIs). Despite these advances, however, chronic immune activation and exhaustion, marked by programmed cell death 1 (PD‐1) and programmed death ligand 1 (PD‐L1) upregulation ...
Bogusz Aksak‐Wąs +8 more
wiley +1 more source
In vitro HIV-1 LTR integration into T-cell activation gene CD27 segment and the decoy effect of modified-sequence DNA. [PDF]
PLoS ONE, 2012 Integration into the host genome is an essential step in the HIV-1 life cycle. However, the host genome sequence that is favored by HIV-1 during integration has never been documented.
Rei Ohmori, Tatsuaki Tsuruyama
doaj +1 more source
HIV Medicine, EarlyView.Abstract Objectives This retrospective, observational, non‐interventional study describes the demographics, characteristics, immunological and virological status, coinfections, healthcare unit of HIV diagnosis and follow‐up status of Ukrainian refugees with newly diagnosed HIV in the Czech Republic, with a special focus on those with a late HIV ...
Zofia Bartovská +20 more
wiley +1 more source
Prevalence of Primary Drug Resistance Against HIV-1 Integrase Inhibitors in Canada
Journal of Acquired Immune Deficiency Syndromes, 2018 To the Editors: An estimated 36.9 million people are living with HIV-1 worldwide,1 of which there are approximately 75,500 infected people in Canada.2 Although varied prevention strategies have been successful in reducing the HIV-1 incidence,3 over 2000 ...
H. Ji +7 more
semanticscholar +1 more source
Obesity Reviews, EarlyView.Summary HIV remains a significant health concern, but the advent of antiretroviral therapy (ART) has transformed it into a manageable chronic condition. However, weight gain and obesity pose a substantial challenge for people living with HIV (PLWH). Moreover, the role of lifestyle has not yet been comprehensively investigated.
Giulia Gilberti +5 more
wiley +1 more source
Scientific Reports, 2018 HIV-Integrase (IN) has proven to be a viable target for highly specific HIV-1 therapy. We aimed to characterize the HIV-1 IN gene in a South African context and identify resistance-associated mutations (RAMs) against available first and second generation
Dominik Brado +7 more
semanticscholar +1 more source
Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley +1 more source
PLoS ONE, 2014 To characterize the HIV-2 integrase gene polymorphisms and the pathways to resistance of HIV-2 patients failing a raltegravir-containing regimen, we studied 63 integrase strand transfer inhibitors (INSTI)-naïve patients, and 10 heavily pretreated ...
Joana Cavaco-Silva +14 more
doaj +1 more source
Latest Progress on Tuberculosis and HIV Co‐Infection: A Closer Look at People of Different Ages
Advanced Therapeutics, Volume 8, Issue 4, April 2025.Tackling the problem of tuberculosis (TB) and human immunodeficiency virus (HIV) co‐infection is a serious global health concern affecting people of all ages. This review presents the characteristics of both diseases, current treatment and diagnostic guidelines, associated problems, innovations in disease management, and overall effects on global ...
Anna Yusuf Aliyu, Oluwatoyin A. Adeleke
wiley +1 more source