Results 161 to 170 of about 86,566 (299)

Structure-function analyses unravel distinct effects of allosteric inhibitors of HIV-1 integrase on viral maturation and integration [PDF]

, 2018
Damien Bonnard, Erwann Le Rouzic, Sylvia Eiler, Céline Amadori, Igor Orlov, Jean‐Michel Bruneau, Julie Brias, Julien Barbion, Francis Chevreuil, Danièle Spehner, Sophie Chasset, Benoît Ledoussal, F. Moreau, Ali Saı̈b, Bruno P. Klaholz, Stéphane Emiliani, Marc Ruff, Alessia Zamborlini, Richard Benarous   +18 more
openalex   +1 more source

1271. HIV-1 Drug Resistance in Patients Failing Integrase Strand Transfer Inhibitor-Based Regimens in Rhode Island, USA

, 2022
Katherine Nagel, Vladimir Novitsky, Su Aung, Matthew D. Solomon, Cindy Won, Amy L. Brotherton, Mark Howison, Fizza S. Gillani, Rami Kantor   +8 more
openalex   +1 more source

Real-World Assessment of Weight Change in People with HIV-1 After Initiating Integrase Strand Transfer Inhibitors or Protease Inhibitors [PDF]

, 2020
Yen‐Wen Chen, Hélène Hardy, Christopher D. Pericone, Wing Chow   +3 more
openalex   +1 more source

Human Vault Nanoparticle Targeted Delivery of Antiretroviral Drugs to Inhibit Human Immunodeficiency Virus Type 1 Infection. [PDF]

, 2019
"Vaults" are ubiquitously expressed endogenous ribonucleoprotein nanoparticles with potential utility for targeted drug delivery. Here, we show that recombinant human vault nanoparticles are readily engulfed by certain key human peripheral blood ...
Anton, Peter A, Deming, Timothy, Elliott, Julie, Fulcher, Jennifer A, Ibarrondo, F Javier, Kickhoefer, Valerie A, Maynard, Heather D, Mrazek, Jan, Rome, Leonard H, Tamshen, Kyle, Wollenberg, Alexander L, Yang, Otto O   +11 more
core  

Isolation of New Chemical Modulators of the Interaction Between HIV-1 Integrase and the Cellular Restriction Factor GCN2

Viruses
Integrase is a key protein during HIV-1 replication as it catalyzes the integration of viral DNA into the host DNA. After several decades of research, highly potent and selective active site inhibitors have emerged.
Chloé Torres, Floriane Lagadec, Eugenia Basyuk, Patricia Recordon-Pinson, Mathieu Métifiot   +4 more
doaj   +1 more source

Cross-clade simultaneous HIV drug resistance genotyping for reverse transcriptase, protease, and integrase inhibitor mutations by Illumina MiSeq [PDF]

, 2014
Dawn M. Dudley, Adam L. Bailey, Shruti H. Mehta, Austin L. Hughes, Gregory D. Kirk, Ryan P. Westergaard, David H. O’Connor   +6 more
openalex   +1 more source

Real-World Assessment of Weight Change in African American Females and Hispanics with HIV-1 After Initiating Integrase Strand-Transfer Inhibitors or Protease Inhibitors

, 2022
Yen‐Wen Chen, David Anderson, Christopher D. Pericone, Prina Donga   +3 more
openalex   +1 more source

Critical appraisal of elvitegravir in the treatment of HIV-1/AIDS

HIV/AIDS: Research and Palliative Care, 2014
Krishan K PandeyInstitute for Molecular Virology, Saint Louis University Health Sciences Center, St Louis, MO, USAAbstract: Human immunodeficiency virus type 1 (HIV-1) integrase inhibitors belong to a novel class of antiretroviral drugs with high potency
Pandey KK
doaj  

An accurate and precise high-performance liquid chromatography method for the rapid quantification of the novel HIV integrase inhibitor raltegravir in human blood plasma after solid phase extraction

, 2020
Naser L. Rezk, Nicole White, Angela D. M. Kashuba   +2 more
openalex   +1 more source

7‐Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir [PDF]

, 2018
Robert Ziegler, Bimbisar Desai, Jo‐Ann Jee, B. Frank Gupton, Thomas D. Roper, Timothy F. Jamison   +5 more
openalex   +1 more source