Results 141 to 150 of about 30,099 (284)
VirusesIntegrase is a key protein during HIV-1 replication as it catalyzes the integration of viral DNA into the host DNA. After several decades of research, highly potent and selective active site inhibitors have emerged.
Chloé Torres +4 more
doaj +1 more source
7‐Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir [PDF]
, 2018 Robert Ziegler +5 more
openalex +1 more source
Critical appraisal of elvitegravir in the treatment of HIV-1/AIDS
HIV/AIDS: Research and Palliative Care, 2014 Krishan K PandeyInstitute for Molecular Virology, Saint Louis University Health Sciences Center, St Louis, MO, USAAbstract: Human immunodeficiency virus type 1 (HIV-1) integrase inhibitors belong to a novel class of antiretroviral drugs with high potency
Pandey KK
doaj
Zhongguo linchuang yanjiuAntiretroviral therapy (ART) has significantly improved the prognosis of HIV/AIDS patients and has become an important global strategy for the prevention and control of AIDS.
HU Zhiliang, YANG Yongfeng
doaj +1 more source
Raltegravir: The First HIV Type 1 Integrase Inhibitor [PDF]
, 2009 Charles B. Hicks, Roy M. Gulick
openalex +1 more source
Pharmacology of boosted and unboosted integrase strand transfer inhibitors for two-dose event-driven HIV prevention regimens among men [PDF]
, 2022 Richard E. Haaland +12 more
openalex +1 more source
From ligand to complexes: inhibition of HIV-1 Integrase by beta-diketo acid metal complexes [PDF]
, 2006 Recently, a class of compounds bearing a β-diketo acid moiety have emerged as the most promising lead in anti-HIV-1 IN drug discovery. It is believed that the β-diketo acid pharmacophoric motif could be involved in a functional sequestration of one or ...
Al-Mawsawi, Laith Q. +8 more
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