Results 41 to 50 of about 651,532 (328)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Recent US Centers for Disease Control and Prevention Activities to Reduce HIV Stigma

Journal of the International Association of Providers of AIDS Care, 2019
HIV stigma affects many persons living with HIV in the United States, and reducing stigma is central to the US Centers for Disease Control and Prevention’s (CDC) mission to promote health and prevent HIV transmission.
Linda Beer PhD, Donna Hubbard McCree PhD, MPH, RPh, William L. Jeffries PhD, MPH, MA, Ansley Lemons MPH, Catlainn Sionean PhD   +4 more
doaj   +1 more source

Impact of HIV-1 CRF55_01B infection on the evolution of CD4 count and plasma HIV RNA load in men who have sex with men prior to antiretroviral therapy

Retrovirology, 2021
Background CRF55_01B is a newly identified HIV-1 circulating recombinant form originated from MSM in China. However, its impact on the disease progression and transmission risk has not been investigated.
Lan Wei, Hao Li, Xing Lv, Chenli Zheng, Guilian Li, Zhengrong Yang, Lin Chen, Xiaoxu Han, Huachun Zou, Yanxiao Gao, Jinquan Cheng, Hui Wang, Jin Zhao   +12 more
doaj   +1 more source

Effectiveness of Male Condoms: Frequently Asked Questions [PDF]

, 2007
More than two decades of research and experience have provided new insights into the role of male condoms for contraception and HIV prevention. However, given that the number of people infected and living with HIV continues to grow, it is essential to ...

core  

Concealment, communication and stigma: The perspectives of HIV-positive immigrant Black African men and their partners living in the United Kingdom [PDF]

, 2015
This study explored the perspectives of Black men, originally from East Africa, living in the United Kingdom and their families on what it means to live with diagnosed HIV.
Abigail Locke, Andrew Clifton, Bob Heyman, Glaser BG, John OA Owuor, Public Health England, Strauss AL, Van Wyk B   +7 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Survey of AIDS Prevention Funders: Which Programs Are Funded, and Why?, A? [PDF]

, 1997
This survey of foundations across the United States asked questions about the amount of money they spend on AIDS and HIV prevention, the types of prevention projects and populations their grants served, and the sources of AIDS information used by the ...
Joshua Schechtel
core  

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou, Carl D. Langefeld, Padmini Sekar, Mary Comeau, Timothy Howard, Tamara N. Kimball, Chen Bowang, Hyacinth I. Hyacinth, Jonathan Rosand, Christopher D. Anderson, Caspar Grond‐Ginsbach, Daniel Woo, Stacie L. Demel   +12 more
wiley   +1 more source

Clinician Perspectives on Delaying Initiation of Antiretroviral Therapy for Clinically Eligible HIV-Infected Patients

Journal of the International Association of Providers of AIDS Care, 2015
Objectives: Guidelines for antiretroviral therapy (ART) initiation have evolved, but consistently note that adherence problems should be considered and addressed. Little is known regarding the reasons providers delay ART initiation in clinically eligible
Linda Beer PhD, Eduardo E. Valverde MPH, Jerris L. Raiford PhD, John Weiser MD, MPH, Becky L. White MD, MPH, Jacek Skarbinski MD   +5 more
doaj   +1 more source