Results 71 to 80 of about 629,767 (276)

Getting to Zero HIV Cases San Francisco: Reconceptualizing Housing as HIV Prevention and HIV Treatment [PDF]

, 2019
The City and County of San Francisco, originallyground zero for the HIV epidemic in the United States, is redefining public health HIV interventions, potentially positioning San Francisco as one of the first major metropolitan cities in the world to ...
Zaragoza, Gaspar
core  

NIBAN2/FLII/RREB1 Axis Drives Glioma Stem Cell Malignancy via TLR3 Pathway Activation

Advanced Science, EarlyView.
NIBAN2, highly expressed in glioma stem‐like cells (GSCs), assembles with FLII and transcription factor RREB1 to form a nuclear complex. This complex transcriptionally activates stemness‐associated genes (e.g., CD44, NANOG) and metabolic enzymes (e.g., LDHA), thereby sustaining both transcriptional and metabolic stemness programs.
Liang liang Shi, Xinwei Qiao, Yue Hu, Minjie Wang, Shaojie Yu, Zihan Gong, Yuxin Rao, Hui Zheng, Siting Chen, Lin Li, Rong Fu, Tao Liang, Jin Yao, Xiaobing Jiang, Junjun Li   +14 more
wiley   +1 more source

A cross-sectional analysis of fingerstick blood self-microcollection for remote HIV suppression monitoring in Atlanta, Georgia, USA: a path to expanding access to continuum of care

AIDS Research and Therapy
Background Many people with HIV experience considerable barriers to accessing HIV clinic services. Options that would permit blood sampling that preclude the need for in-clinic visits and increase privacy would aid in overcoming many of the obstacles ...
Jeffrey A. Johnson, Amanda J. Smith, Ruth Dana, Erin Rogers, M. Leanne Ward, Ariana S. Tino, Vickie Sullivan, Wei Luo, Jin-fen Li, Patrick S. Sullivan   +9 more
doaj   +1 more source

Spatial distribution of HIV, HCV, and co-infections among drug users in the southwestern border areas of China (2004–2014): a cohort study of a national methadone maintenance treatment program

BMC Public Health, 2017
Background A methadone maintenance treatment (MMT) program to curb the dual epidemics of HIV/AIDS and drug use has been administered by China since 2004. Little is known regarding the geographic heterogeneity of HIV and hepatitis C virus (HCV) infections
Mingli Li, Rongjian Li, Zhiyong Shen, Chunying Li, Nengxiu Liang, Zhenren Peng, Wenbo Huang, Chongwei He, Feng Zhong, Xianyan Tang, Guanghua Lan   +10 more
doaj   +1 more source

Emerging priorities for HIV service delivery [PDF]

, 2020
Nathan Ford and co-authors discuss global priorities in the provision of HIV prevention and treatment ...
et al.,, Ford, Nathan, Geng, Elvin
core   +1 more source

HIV testing intervention development among men who have sex with men in the developed world [PDF]

, 2017
HIV testing is a ‘gateway’ technology, enabling access to treatment and HIV prevention. Biomedical approaches to prevention, such as pre-exposure prophylaxis and treatment as prevention, require accurate and regular HIV test results.
Burns, Fiona, Estcourt, Claudia, Flowers, Paul, Sonnenberg, Pam   +3 more
core   +4 more sources

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Marburg Virus Disease Surveillance in the Community Through Active Case Finding in Rwanda, 2024

International Journal of Infectious Diseases
Background: Marburg Virus Disease (MVD) is a high-threat pathogen with a high case fatality rate and rapid human-to-human transmission, posing serious public health risks.
Frederic Ntirenganya, Edouard Ruseesa, Olivier Nsekuye, Noella Benemariya, Bruce Rwagitinywa, Aphrodis Hagabimana, Hugues Valois Mucunguzi, Edson Rwagasore   +7 more
doaj   +1 more source

Proven HIV Prevention Strategies [PDF]

, 2009
Describes strategies that, used in combination, have proven to be effective in preventing sexual, blood-borne, and mother-to-child transmission of HIV.

core  

“More” Artificial mRNAs: Beyond the Art of Nature

Advanced Science, EarlyView.
Inspired by nature yet transcending it, synthetic mRNA is being redesigned beyond the canonical architecture. This review highlights emerging forms—circular, branched, and self‐amplifying mRNAs—that expand stability, persistence, and functional control, illustrating how artificial mRNA is evolving into a new medium for programmable biological ...
Yuanzhe Cui, Minami Fukui, Hirohisa Ohno, Hirohide Saito   +3 more
wiley   +1 more source