Results 171 to 180 of about 106,865 (295)

AlphaFold2‐Guided Cyclic Peptide Stabilizer Design to Target Protein–Protein Interactions

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 7, Page 1356-1370, July 2026.
ABSTRACT The control and modulation of protein–protein interactions (PPIs) is of central importance for the majority of biological processes and most biomedical applications. Stabilization of PPIs, besides inhibition, is of growing pharmaceutical interest.
Niklas Halbwedl, Martin Zacharias
wiley   +1 more source

Advancements in development of novel class of HIV protease inhibitors. [PDF]

Ann Med
Gu WG, Yin GZ, Zhang YP.
europepmc   +1 more source

HIV Protease and Integrase Empirical Substitution Models of Evolution: Protein-Specific Models Outperform Generalist Models. [PDF]

Genes (Basel), 2021
Del Amparo R, Arenas M.
europepmc   +1 more source

Food crisis, household welfare and HIV/AIDS treatment : evidence from Mozambique [PDF]

Using panel data from Mozambique collected in 2007 and 2008, the authors explore the impact of the food crisis on the welfare of households living with HIV/AIDS.
Kazianga, Harounan, Vaillant, Julia, de Walque, Damien, Over, Mead   +3 more
core  

Affinity Proteomics‐Based Non‐Invasive Detection of Clinically Significant Liver Disease

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 1, Page 74-88, July 2026.
Using UK Biobank proteomic data, we identified a five‐protein score reflecting hepatic stellate cell activation and hepatocellular injury that predicts major adverse liver outcomes and clinically significant fibrosis, with consistent performance validated in two independent cohorts (patients with HIV and alpha1‐antitrypsin deficiency).
Sriram Balasubramani, Katharina Remih, Anna Sophie Karl, Julia Alexandra Borchert, Christina Schrader, Malin Fromme, Can Kayatekin, Bailin Zhang, Mikhail Levit, Pavithra Krishnaswami, Louise E. van Eekeren, Leo A. B. Joosten, Twan Otten, Petra Tomanová, Pavel Strnad   +14 more
wiley   +1 more source

Recent Advances in Heterocyclic HIV Protease Inhibitors. [PDF]

Int J Mol Sci
Funicello M, Chiummiento L, Santarsiere A, Poggio F, Lupattelli P.   +4 more
europepmc   +1 more source

Antiretroviral therapy and the lipodystrophy syndrome

, 2001
Lipodystrophy syndrome’ in the setting of HIV infection has come to encompass a collection of morphological and metabolic abnormalities linked with the use of antiretroviral therapy and other risk factors.
Nolan, D., John, M., Mallal, S.
core  

Glycolytic metabolism of CD8+ T‐cells affects susceptibility to human leukocyte antigen‐mediated abacavir‐induced hypersensitivity

British Journal of Pharmacology, Volume 183, Issue 13, Page 3743-3761, July 2026.
Abstract Background and Purpose Drug hypersensitivity reactions (DHRs) associated with a specific human leukocyte antigen (HLA) allotype do not manifest uniformly in all individuals within an HLA model population. This scenario highlights the complexity of predicting drug hypersensitivity reaction risk without considering additional factors ...
Takeshi Susukida, Yuchen Sun, Noriaki Arakawa, Takuya Hirao, Tadahaya Mizuno, Shigeki Aoki, Kousei Ito, Yoshihiro Hayakawa   +7 more
wiley   +1 more source

Safety of protease inhibitors in HIV-infected pregnant women

, 2013
Imène Chougrani,1 Dominique Luton,1,2 Sophie Matheron,3 Laurent Mandelbrot,2,4 Elie Azria1,2 1Department of Obstetrics and Gynecology, Bichat Claude Bernard Hospital, Paris Diderot University, Paris, 2Departement Hospitalo-Universitaire "Risk and ...
Chougrani I, Luton D, Azria E, Matheron S, Mandelbrot L   +4 more
core  

Guidelines for Comparing Circular Dichroism Spectroscopy and Molecular Dynamics Simulations for Biomolecules

ChemPhysChem, Volume 27, Issue 12, 26 June 2026.
A direct comparison is made between circular dichroism (CD) spectroscopy and molecular dynamics (MD) simulations for studying peptide partitioning through biological membranes. The assumptions and limitations of each method is discussed, and case studies are provided for their use.
Cinzia Campus, Marta Roldo, Charles H. Chen, Roja Hadianamrei, Elisabetta Gavini, Christian Jorgensen   +5 more
wiley   +1 more source