Results 161 to 170 of about 106,865 (295)

Reduced SH3RF3 May Protect Against Alzheimer's Disease by Lowering Microglial Pro‐Inflammatory Responses via Modulation of JNK and NFkB Signaling

Glia, Volume 74, Issue 7, July 2026.
SNPs in SH3RF3 decrease the age of onset of Alzheimer's disease (AD). Reduced SH3RF3 blunts human microglial JNK and NFkB signaling and downstream inflammatory cytokine production, which may partially explain how SH3RF3 SNPs protect against AD. ABSTRACT Understanding how high‐risk individuals are protected from Alzheimer's disease (AD) may illuminate ...
Ronak Patel, Rong Cheng, Christopher L. Cardona, Ellen Angeles, Gunjandeep Singh, Sabrina Miller, Archana Ashok, Andrew F. Teich, Angel Piriz, Aleyda Maldonado, Ivonne Z. Jiménez‐Velázquez, Richard Mayeux, Joseph H. Lee, Andrew A. Sproul   +13 more
wiley   +1 more source

Revertant mutation V48G alters conformational dynamics of highly drug resistant HIV protease PRS17. [PDF]

J Mol Graph Model, 2021
Burnaman SH, Kneller DW, Wang YF, Kovalevsky A, Weber IT.   +4 more
europepmc   +1 more source

Unintended Consequences of Life‐Saving Pharmaceutical Innovations: How HAART Led to the Resurgence of Syphilis

Health Economics, Volume 35, Issue 7, Page 1118-1130, July 2026.
ABSTRACT Syphilis, a sexually transmitted infection that can lead to serious health complications, was almost eliminated in the United States by 2000. But since then, its incidence began to increase, recently reaching a 60‐year peak. We suggest that the introduction of the highly active antiretroviral therapy (HAART) drug regimen, which transformed HIV
David Beheshti, Scott Cunningham, Nir Eilam   +2 more
wiley   +1 more source

Evolution of drug resistance in HIV protease. [PDF]

BMC Bioinformatics, 2020
Shah D, Freas C, Weber IT, Harrison RW.
europepmc   +1 more source

Suspected bradycardia due to interactions between HIV protease inhibitors and lidocaine: a case report. [PDF]

J Dent Anesth Pain Med, 2021
Hamaya E, Kamekura N, Fujisawa T.
europepmc   +1 more source

Is use of antiretroviral therapy among homosexual men associated with increased risk of transmission of HIV infection?

, 2003
Background/objective: There is concern that use of highly active antiretroviral therapy (HAART) may be linked to increased sexual risk behaviour among homosexual men.
Hart, GJ, Stephenson, Jodie, Copas, AJ, Davidson, OR, Mercer, C. H., Imrie, John, Williams, IG, Williams, I. G., Davis, MMD, Davis, M, Imrie, J, Copas, A. J., Black, S, Hart, G, Davidson, O. R., Stephenson, JM, Mercer, C   +16 more
core  

HIV Care Retention and Cost Analysis in Multi‐Month ART Dispensing: A Randomized Controlled Trial in China

Journal of the International AIDS Society, Volume 29, Issue 7, July 2026.
ABSTRACT Introduction Multi‐month dispensing (MMD), as a differentiated service delivery model, can reduce the frequency of clinic visits, waiting time and travel costs for clinically stable people living with HIV. This study aimed to evaluate the impact of 6‐month MMD of antiretroviral therapy (ART) on retention and conduct a cost analysis in China ...
Wenqi Shang, Yanyan Zhu, Ying He, Xiaolin Li, Qinghai Hu, Hong Sun, Wenqing Geng, Hong Shang, Haibo Ding   +8 more
wiley   +1 more source

Forecasting drug resistant HIV protease evolution. [PDF]

PLoS Comput Biol
Aggarwal M, Periwal V.
europepmc   +1 more source

HIV Protease Inhibitors and Insulin Sensitivity: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

Front Pharmacol, 2021
Kajogoo VD, Gorret Atim M, Amare D, Geleta M, Muchie Y, Tesfahunei HA, Olomi W, Acam J, Manyazewal T.   +8 more
europepmc   +1 more source

Genetic heterogenicity of HIV-1 protease in drug-naive and drug-treated HIV-positive patients

, 2002
Genetic heterogenicity of HIV-1 protease in drug-naive and drug-treated HIV-positive ...
Erba F, Giannella S, Ceccherini Silberstein F, Bertoli A, Forbici F, Bellocchi MC, Antinori A, D’Arminio Monforte A, D’Arrigo R, Balotta C, Perno CF, Gori C, Trotta MP   +12 more
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