Results 281 to 290 of about 260,498 (362)

Role of protease inhibitor 9 in survival and replication of Mycobacterium tuberculosis in mononuclear phagocytes from HIV-1-infected patients

, 2014
Zahra Toossi, Mianda Wu, Shigou Liu, Christina S. Hirsch, Jessica Walrath, S. Marieke van Ham, Richard F. Silver   +6 more
openalex   +1 more source

TDP‐43 proteinopathies and neurodegeneration: insights from Caenorhabditis elegans models

The FEBS Journal, Volume 293, Issue 2, Page 348-384, January 2026.
The manuscript explores structural and functional features of TDP‐43 and its worm homologue, TDP‐1, highlighting conserved and divergent structural and functional features. Using genetically engineered C. elegans models, key pathological features of TDP‐43 proteinopathies—including aggregation, neurodegeneration, and motor deficits—are recapitulated ...
Ghulam Jeelani Pir, Joerg Buddenkotte, Majid Ali Alam, Ahmed Own, Randall J. Eck, Brian C. Kraemer, Eckhard Mandelkow, Martin Steinhoff   +7 more
wiley   +1 more source

Targeting the AKT pathway: Repositioning HIV protease inhibitors as radiosensitizers.

Indian J Med Res, 2016
Goda JS, Pachpor T, Basu T, Chopra S, Gota V.   +4 more
europepmc   +1 more source

Recent Progress in Double Filtration Plasmapheresis

Hemodialysis International, Volume 30, Issue 1, Page 18-25, January 2026.
ABSTRACT Double‐filtration plasmapheresis is an advanced extracorporeal blood purification technique that selectively removes pathogenic macromolecules based on molecular weight. Unlike conventional plasma exchange, double‐filtration plasmapheresis uses a two‐step filtration process to retain beneficial plasma components such as albumin, while ...
Dan Li, Xiaoqiang Liu, Yuhan Wang, Wenxuan Ji   +3 more
wiley   +1 more source

Design, synthesis, X-ray studies, and biological evaluation of novel macrocyclic HIV-1 protease inhibitors involving the P1′-P2′ ligands

, 2017
Arun K. Ghosh, W. Sean Fyvie, Margherita Brindisi, Melinda Steffey, Johnson Agniswamy, Yuan-Fang Wang, Manabu Aoki, Masayuki Amano, Irene T. Weber, Hiroaki Mitsuya   +9 more
openalex   +2 more sources

Outcomes of real‐world initiation of long‐acting injectable cabotegravir and rilpivirine (LA‐I CAB + RPV) in individuals with viraemia: A systematic review of baseline characteristics, virological failure outcomes and discontinuations

HIV Medicine, Volume 27, Issue 1, Page 42-57, January 2026.
Abstract Background When using long‐acting injectable cabotegravir and rilpivirine (CAB + RPV) in individuals with viraemia, beyond small cohorts, little is known about baseline characteristics, virological failure outcomes, resistance emergence, re‐suppression and discontinuation.
Alexa Elias, Chloé Pasin, Melanie Smuk, Amy Paterson, Chloe M. Orkin   +4 more
wiley   +1 more source

Intersections of vitamin D deficiency, HIV and chronic liver diseases

HIV Medicine, Volume 27, Issue 1, Page 4-17, January 2026.
Abstract Objectives Despite effective antiretroviral therapy (ART), chronic liver diseases remain a leading cause of morbidity and mortality among people with HIV, with metabolic dysfunction–associated steatotic liver disease (MASLD) now the predominant etiology. Vitamin D deficiency is also highly prevalent in this population.
Francesca Farina, Aurgho Datta, Suzanne N. Morin, Sahar Saeed, Bertrand Lebouche, Giovanni Guaraldi, Salvatore Petta, Giada Sebastiani   +7 more
wiley   +1 more source

Synthesis of 5,6-Dihydro-4-hydroxy-2- pyrones as HIV-1 Protease Inhibitors:  The Profound Effect of Polarity on Antiviral Activity

, 1997
Susan E. Hagen, J. V. N. Vara Prasad, F Boyer, John M. Domagala, Edmund L. Ellsworth, Christopher Gajda, Harriet W. Hamilton, Larry J. Markoski, Bruce A. Steinbaugh, Bradley D. Tait, Elizabeth A. Lunney, Peter J. Tummino, Donna Ferguson, Donald Hupe, Carolyn Nouhan, Stephen J. Gracheck, James M. Saunders, Steven VanderRoest   +17 more
openalex   +1 more source

People living with HIV on modern antiretrovirals do not display a pro‐atherogenic lipid profile and have similar body composition compared to healthy controls

HIV Medicine, Volume 27, Issue 1, Page 86-95, January 2026.
Abstract Objectives Alterations in lipids and apolipoproteins contribute to cardiovascular disease (CVD) and are common in people with HIV. The aim of our study was to compare lipid profiles and body composition between people with and without HIV and to explore whether any associations with HIV could be explained by socio‐demographic, clinical ...
S. Savinelli, A. Heeney, W. Tinago, A. A. Garcia Leon, P. McGettrick, A. G. Cotter, I. Walsh, M. Fitzgibbon, C. A. Sabin, P. W. G. Mallon, E. R. Feeney, on behalf of the HIV UPBEAT study group   +11 more
wiley   +1 more source

National representative survey of pretreatment HIV drug resistance in Colombia: analysis of antiretroviral resistance-associated mutations using next-generation sequencing. [PDF]

J Antimicrob Chemother
Martínez-Buitrago E, Zapata-Marín AF, Rubiano LC, Sañudo LM, Oñate JM, Lenis W, García-Góez JF, Álvarez JE, García-Morales C, Matías-Florentino M, Ávila-Ríos S.   +10 more
europepmc   +1 more source