Results 51 to 60 of about 209,011 (190)

Neuropathy among drug resistant HIV Patients treated in Jakarta

Journal of Infection in Developing Countries
Introduction: Some people living with HIV (PLWH) receiving ART in Indonesia display poor clearance of replicating virus. This has been associated with HIV-associated sensory neuropathy.
Ibnu A Ariyanto, Fitri Octaviana, Churi Wardah, Ekawati Beti, Silvia Widyaningtyas, Budiman Bela, Patricia Price, Amin Soebandrio   +7 more
doaj   +1 more source

Trends in Utilization of Statin Therapy and Contraindicated Statin Use in HIV‐‐Infected Adults Treated With Antiretroviral Therapy From 2007 Through 2015

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background HIV is associated with an increased risk for atherosclerotic cardiovascular disease, which may result in many people living with HIV taking a statin.
Robert S. Rosenson, Lisandro D. Colantonio, Greer A. Burkholder, Ligong Chen, Paul Muntner   +4 more
doaj   +1 more source

Virtual Screening for HIV Protease Inhibitors: A Comparison of AutoDock 4 and Vina

PLoS ONE, 2010
Background The AutoDock family of software has been widely used in protein-ligand docking research. This study compares AutoDock 4 and AutoDock Vina in the context of virtual screening by using these programs to select compounds active against HIV ...
M. Chang, Christian Ayeni, S. Breuer, B. Torbett   +3 more
semanticscholar   +1 more source

Peptide aldehydes as inhibitors of HIV protease

FEBS Letters, 1993
We have recently shown that α‐MAPI, a peptidic aldehyde of microbial origin, inhibits the HIV protease with a potency comparable to pepstatin, having, differently from pepstatin, no activity on other aspartic proteases. In this study different peptide derivatives containing a C‐terminal aldehyde have been tested to assess the potential of this function
E. Sarubbi, P. Seneci, M. R. Angelastro, N. P. Peet, M. Denaro, K. Islam   +5 more
openaire   +2 more sources

HIV Protease Inhibitors: Effect on the Opportunistic Protozoan Parasites

Open Medicinal Chemistry Journal, 2011
The impact of highly active antiretroviral therapy (HAART) in the natural history of AIDS disease has been allowed to prolong the survival of people with HIV infection, particularly whose with increased HIV viral load.
Y. Alfonso, L. Monzote
semanticscholar   +1 more source

Diagnosis, antiretroviral therapy, and emergence of resistance to antiretroviral agents in HIV-2 infection: a review

Brazilian Journal of Infectious Diseases
Human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) are the causative agents of AIDS. HIV-2 is prevalent at moderate to high rates in West African countries, such as Senegal, Guinea, Gambia, and Cape Verde.
Maia Hightower, Esper Georges Kallas
doaj   +1 more source

High-affinity RNA Aptamers Against the HIV-1 Protease Inhibit Both In Vitro Protease Activity and Late Events of Viral Replication

Molecular Therapy: Nucleic Acids, 2015
HIV-1 aspartyl protease (PR) plays a key role in virion morphogenesis, underscoring the effectiveness of protease inhibitors (PI). Despite their utility, side effects and drug-resistance remains a problem.
Sonald Duclair, Archana Gautam, Andrew Ellington, Vinayaka R Prasad   +3 more
doaj   +1 more source

HIV Protease Inhibitors Apoptotic Effect in SH-SY5Y Neuronal Cell Line

Cellular Physiology and Biochemistry, 2016
Background: Prophylactic treatment regimens to prevent mother-to-child HIV transmission include protease inhibitors Lopinavir and Ritonavir. Lopinavir and Ritonavir have been reported to be able to induce intracellular oxidative stress in diverse ...
Paola Maura Tricarico, Rafael Freitas de Oliveira Franca, Sabrina Pacor, Valentina Ceglia, Sergio Crovella, Fulvio Celsi   +5 more
doaj   +1 more source

Drogas anti-VIH: passado, presente e perspectivas futuras Drugs anti-HIV: past, present and future perspectives

Química Nova, 2003
Currently available anti-HIV drugs can be classified into three categories: nucleoside analogue reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs) and protease inhibitors (PIs).
Marcus Vinícius Nora de Souza, Mauro Vieira de Almeida   +1 more
doaj   +1 more source

Influence of Drug Transport Proteins on Pharmacokinetics and Drug Interactions of HIV Protease Inhibitors

Journal of Pharmacy and Science, 2011
Protease inhibitors, a class of antiretroviral agents frequently used in the treatment of HIV infection, interact with numerous transport proteins resulting in clinically significant drug-drug interactions (DDIs). This review focuses on the proteins that
LaToya M. Griffin, P. Annaert, K. Brouwer   +2 more
semanticscholar   +1 more source