Results 31 to 40 of about 1,065 (135)
Zhongguo shiyan zhenduanxue, 2010 目的评价靶向Hiwi基因的shRNA表达载体的干扰效果。方法通过构建靶向Hiwi基因的短发夹RNA（shout-hairpin RNA,shRNA）真核表达载体pGenesil-2-Hiwi1和pGenesil-2-Hiwi2263,并以pGenesil-2-control为阴性对照,转染膀胱癌T24细胞,从mRNA和蛋白水平观察3种干扰载体的干扰效率。结果pGenesil-2-Hiwi1和pGenesil-2-Hiwi2263组膀胱癌T24细胞Hiwi mRNA与GAPDH灰度比值较Normal ...
陈岐辉 +4 more
doaj
Berichte zur Wissenschaftsgeschichte, Volume 48, Issue 3, Page 266-289, October 2025.Wie kann man einen historischen Blick auf das eigene Fach werfen? Diese Frage ist nicht einfach zu beantworten – will man einerseits nicht in einer Nabelschau und Hagiographie enden, andererseits aber auch keinen umfassenden Entwurf einer zukünftigen Historiographie vorlegen.
Soraya de Chadarevian +2 more
wiley +1 more source
The universal overexpression of a cancer testis antigen hiwi is associated with cancer angiogenesis
Oncology Reports, 2010 The aim of this study was to determine whether the universal overexpression of hiwi is associated with cancer angiogenesis. The difference of mRNA expression in blood vessels derived from DLBCL and RLNH tissues was detected, and hiwi was overexpressed in tumor vessels of lymphoma.
Shuang, Li +8 more
openaire +4 more sources
Zhongguo shiyan zhenduanxue, 2008 目的构建靶向HIWI基因的shRNA真核表达载体质粒,为利用RNA干扰技术探索HIWI基因的作用的研究做准备。方法根据HIWI mRNA序列设计并合成shRNA寡核苷酸片段,退火形成双链并连接入pGenesil-2载体,并进行酶切鉴定和测序。结果酶切证明构建的shRNA已插入载体中,经测序证明与设计相同。结论成功构靶向HIWI基因的shRNA真核表达载体,为进一步研究HIWI基因在干细胞和肿瘤细胞中的作用机制及后续的体内外RNAi实验研究奠定了基础。
陈岐辉 +4 more
doaj
Use of community characteristics to predict hunting and game harvests in western Amazonian forests
Conservation Biology, Volume 39, Issue 4, August 2025.Abstract Wild game harvesting in Amazonia provides rural residents with protein and cash income but can threaten wildlife populations and forest ecosystem functions. As yet, the socioeconomic and environmental drivers that shape hunter livelihoods remain poorly understood.
Daniel Zayonc +4 more
wiley +1 more source
Immunity, Inflammation and Disease, Volume 12, Issue 6, June 2024.Cancer‐testis antigens (CTAs) exhibit carcinogenic potential and strong immunogenicity in ovarian cancer. This review outlines a comprehensive of overview the regulatory mechanism, immunogenicity, clinical expression significance, tumorigenesis, and application prospects of CTAs in ovarian cancer, all of which can provide novel insights in the ...
Lina Lin +7 more
wiley +1 more source
Hiwi Promotes the Proliferation of Colorectal Cancer Cells via Upregulating Global DNA Methylation [PDF]
Disease Markers, 2015 Hiwi is well known for its role in stem cell renewal, maintaining the resting stage, and downregulating cell cycle of stem cells via RNA silencing. And Hiwi overexpression has been recognized in several types of cancers. In the present study, we examined the Hiwi expression in colorectal cancer (CRC) specimens in both mRNA and protein levels via real ...
Yang, Lin +6 more
openaire +2 more sources
Effect of betulinic acid on the regulation of Hiwi and cyclin B1 in human gastric adenocarcinoma AGS cells [PDF]
Acta Pharmacologica Sinica, 2009 To investigate the effect of betulinic acid (BA) on the proliferation, apoptosis and cell cycle of gastric adenocarcinoma cell AGS in vitro and the underlying mechanism.The effect of BA on the proliferation of AGS cells was measured by using 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium (MTT) assay.
Li-jing, Yang +6 more
openaire +2 more sources
Zhongguo shiyan zhenduanxue, 2009 目的检测Hiwi基因在膀胱移行细胞癌组织切片中的表达情况。方法应用免疫组织化学方法,对Hiwi基因在膀胱癌组织切片中的表达情况进行检测。结果Hiwi蛋白表达的阳性细胞百分率在不同临床分期的膀胱移行细胞癌即浅表性膀胱癌（Tis、Ta、T1）和浸润性膀胱癌（T2、T3、T4）之间存在显著性差异 ...
陈岐辉 +4 more
doaj
International Indigenous Policy Journal, 2014 In this article, I examine how the process of Indigenous participation in policy-making pertaining to the development of federal sport policy in Canada is connected to Indigenous forms of self-determination.
Braden P. Te Hiwi
doaj