Results 41 to 50 of about 1,066 (136)

Hiwi facilitates chemoresistance as a cancer stem cell marker in cervical cancer

open access: yesOncology Reports, 2014
Hiwi, also named PiwiL1, is a human homologue of the Piwi family which is associated with stem cells and is overexpressed in several types of cancers. In the present study, we aimed to investigate the role of Hiwi in cervical carcinogenesis. Immunochemical analysis showed a significantly higher frequency of Hiwi staining in high-grade squamous ...
Wei, Liu   +7 more
openaire   +3 more sources

The universal overexpression of a cancer testis antigen hiwi is associated with cancer angiogenesis

open access: yesOncology Reports, 2010
The aim of this study was to determine whether the universal overexpression of hiwi is associated with cancer angiogenesis. The difference of mRNA expression in blood vessels derived from DLBCL and RLNH tissues was detected, and hiwi was overexpressed in tumor vessels of lymphoma.
Shuang, Li   +8 more
openaire   +4 more sources

Hiwi Promotes the Proliferation of Colorectal Cancer Cells via Upregulating Global DNA Methylation [PDF]

open access: yesDisease Markers, 2015
Hiwi is well known for its role in stem cell renewal, maintaining the resting stage, and downregulating cell cycle of stem cells via RNA silencing. And Hiwi overexpression has been recognized in several types of cancers. In the present study, we examined the Hiwi expression in colorectal cancer (CRC) specimens in both mRNA and protein levels via real ...
Yang, Lin   +6 more
openaire   +2 more sources

Bausteine zu einer Oral History der Wissenschaftsgeschichte Auf der Suche: von der Biologie und der Philosophie zur Wissenschaftsgeschichte. Interview mit Soraya de Chadarevian

open access: yesBerichte zur Wissenschaftsgeschichte, Volume 48, Issue 3, Page 266-289, October 2025.
Wie kann man einen historischen Blick auf das eigene Fach werfen? Diese Frage ist nicht einfach zu beantworten – will man einerseits nicht in einer Nabelschau und Hagiographie enden, andererseits aber auch keinen umfassenden Entwurf einer zukünftigen Historiographie vorlegen.
Soraya de Chadarevian   +2 more
wiley   +1 more source

Use of community characteristics to predict hunting and game harvests in western Amazonian forests

open access: yesConservation Biology, Volume 39, Issue 4, August 2025.
Abstract Wild game harvesting in Amazonia provides rural residents with protein and cash income but can threaten wildlife populations and forest ecosystem functions. As yet, the socioeconomic and environmental drivers that shape hunter livelihoods remain poorly understood.
Daniel Zayonc   +4 more
wiley   +1 more source

Hiwi基因在膀胱移行细胞癌组织切片中的表达

open access: yesZhongguo shiyan zhenduanxue, 2009
目的检测Hiwi基因在膀胱移行细胞癌组织切片中的表达情况。方法应用免疫组织化学方法,对Hiwi基因在膀胱癌组织切片中的表达情况进行检测。结果Hiwi蛋白表达的阳性细胞百分率在不同临床分期的膀胱移行细胞癌即浅表性膀胱癌(Tis、Ta、T1)和浸润性膀胱癌(T2、T3、T4)之间存在显著性差异 ...
陈岐辉   +4 more
doaj  

The potential value of cancer‐testis antigens in ovarian cancer: Prognostic markers and targets for immunotherapy

open access: yesImmunity, Inflammation and Disease, Volume 12, Issue 6, June 2024.
Cancer‐testis antigens (CTAs) exhibit carcinogenic potential and strong immunogenicity in ovarian cancer. This review outlines a comprehensive of overview the regulatory mechanism, immunogenicity, clinical expression significance, tumorigenesis, and application prospects of CTAs in ovarian cancer, all of which can provide novel insights in the ...
Lina Lin   +7 more
wiley   +1 more source

Manaca, Batata y Ñame: Posibles Sustitutos del Trigo en Alimentos para dos Etnias del Amazonas Venezolano Manaca, Sweet Potato and Yam: Possible Substitutes Of Wheat in Foods for two Ethnic Population in Venezuelan Amazon

open access: yesArchivos Latinoamericanos de Nutrición, 2006
En este estudio se obtuvieron harinas a partir de la manaca o acai (Euterpe oleracea Mart), de la batata (Ipomea batatas), y del ñame (Dioscorea spp.), especies vegetales cultivadas en el Amazonas venezolano.
Elba Sangronis   +4 more
doaj  

Suppression of Hiwi inhibits the growth and epithelial‑mesenchymal transition of cervical cancer cells

open access: yesOncology Letters, 2018
Cervical cancer is a common gynecological malignancy. Hiwi exhibits a high level of expression in cervical cancer cells. However, the effects of Hiwi expression in cervical cancer cells remain unresolved. In the present study, the effects of Hiwi downregulation on the growth and epithelial-mesenchymal transition of cervical cancer cells were ...
Guangjun, Pei, Baojian, Li, Anjun, Ma
openaire   +3 more sources

The Role of Hiwi in Stem Cell Maintenance and Sarcomagenesis

open access: yes, 2012
Sarcomas are cancers of connective tissues, such as bone, adipose and cartilage, and are thought to arise from the aberrant development of the mesenchyme. As such, mesenchymal stem cells are thought to be the cell of origin for sarcomas. Genetic or epigenetic lesions at particular points during the differentiation of a mesenchymal stem cell into its ...
openaire   +2 more sources

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