Results 21 to 30 of about 1,065 (135)

Reconstructing prehistoric demography: What role for extant hunter‐gatherers?

open access: yesEvolutionary Anthropology: Issues, News, and Reviews, Volume 29, Issue 6, Page 332-345, November/December 2020., 2020
Abstract Demography is central to biological, behavioral, and cultural evolution. Knowledge of the demography of prehistoric populations of both Homo sapiens and earlier members of the genus Homo is, therefore, key to the study of human evolution.
Abigail E. Page, Jennifer C. French
wiley   +1 more source

Reversing Lanmodulin's Metal‐Binding Sequence in Short Peptides Surprisingly Increases the Lanthanide Affinity

open access: yesAngewandte Chemie, Volume 137, Issue 46, November 10, 2025.
Accidentally reversing the lanthanide‐binding sequences of lanmodulin‐inspired short peptides lead to the serendipitous discovery of a set of peptides with a one order of magnitude higher lanthanide‐binding affinity than the uncapped peptides synthesised in the correct direction.
Sophie M. Gutenthaler‐Tietze   +5 more
wiley   +2 more sources

Direct Differentiation of Human Pluripotent Stem Cells into Haploid Spermatogenic Cells

open access: yesCell Reports, 2012
Human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) have been shown to differentiate into primordial germ cells (PGCs) but not into spermatogonia, haploid spermatocytes, or spermatids.
Charles A. Easley, IV   +10 more
doaj   +1 more source

Genetic disorders and male infertility

open access: yesReproductive Medicine and Biology, Volume 19, Issue 4, Page 314-322, October 2020., 2020
Abstract Background At present, one out of six couples is infertile, and in 50% of cases, infertility is attributed to male infertility factors. Genetic abnormalities are found in 10%‐20% of patients showing severe spermatogenesis disorders, including non‐obstructive azoospermia.
Shinnosuke Kuroda   +6 more
wiley   +1 more source

The role of HIWI in stem cell maintenance and sarcomagenesis.

open access: yesJournal of Clinical Oncology, 2011
e20500 Background: PIWI proteins comprise a highly conserved protein family that promote genomic integrity during early development via small RNA-mediated gene silencing and DNA methylation-mediate...
S. Siddiqi, M. Terry, I. Matushansky
openaire   +2 more sources

Common genetic polymorphisms of microRNA biogenesis pathway genes and breast cancer survival

open access: yesBMC Cancer, 2012
Background Although the role of microRNA’s (miRNA’s) biogenesis pathway genes in cancer development and progression has been well established, the association between genetic variants of this pathway genes and breast cancer survival is still unknown ...
Sung Hyuna   +10 more
doaj   +1 more source

Comparison of a 3D‐printed skin model with established methods for teaching punch biopsy with suturing

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Realistic and accessible models are essential for training physicians in clinical procedures. This study investigated whether a cost‐effective 3D‐printed skin model is superior to fruit and foam models for teaching skin biopsies. Patients and Methods The study (10/2023‐02/2025) involved 148 medical students who compared the 3D skin ...
Sandra Schuh   +5 more
wiley   +1 more source

Vergleich eines 3D‐gedruckten Hautmodells mit etablierten Methoden zur Lehre der Stanzbiopsie mit Nahtversorgung

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Zusammenfassung Hintergrund Realistische Trainingsmodelle sind essenziell, um Ärztinnen und Ärzte in klinischen Prozeduren zu schulen. In dieser Studie wurde untersucht, ob ein kostengünstiges, selbst generiertes 3D‐gedrucktes Hautmodell Früchten und Schaumstoffmodellen beim Erlernen von Hautstanzen überlegen ist.
Sandra Schuh   +5 more
wiley   +1 more source

Expression of hiwi gene in human gastric cancer was associated with proliferation of cancer cells [PDF]

open access: yesInternational Journal of Cancer, 2005
AbstractStem cell genetics research may be critical to our understanding of carcinogenesis, as both stem cells and cancer cells possess the ability to self‐renew. Recent discoveries have indicated that the piwi family of genes plays an essential role in stem cell self‐renewal in diverse organisms.
Xiaoying, Liu   +10 more
openaire   +2 more sources

Menopause Averted a Midlife Energetic Crisis With Help From Older Dependent Children and Parents: A Simulation Study

open access: yesAmerican Journal of Biological Anthropology, Volume 190, Issue 3, July 2026.
ABSTRACT Objectives The grandmother hypothesis proposes that ancestral women ceased reproduction midlife to instead provision their grandchildren. An alternative “two‐sex” account proposes that the high energetic burden of caring for slow‐developing offspring was met with biparental investment.
Edward H. Hagen
wiley   +1 more source

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