Results 21 to 30 of about 1,066 (136)
Vision Mātauranga research directions: opportunities for iwi and hapū management plans
Kōtuitui: New Zealand Journal of Social Sciences Online, Volume 16, Issue 2, Page 371-383, November 2021., 2021 ABSTRACT The Ministry of Business, Innovation and Employment (MBIE) Vision Mātauranga policy has created a clear message for researchers in Aotearoa/New Zealand – that research conducted in Aotearoa New Zealand should recognise and support the ‘unlocking of the innovative potential of Māori for the benefit of all New Zealand’ and be designed with a ...
Lucy H. Kaiser, Wendy S. A. Saunders
wiley +1 more source
Genetic variations in key microRNA processing genes and risk of head and neck cancer: a case-control study in Chinese population. [PDF]
PLoS ONE, 2012 MicroRNAs (miRNAs) have been reported to play a key role in oncogenesis. Genetic variations in miRNA processing genes and miRNA binding sites may affect the biogenesis of miRNA and the miRNA-mRNA interactions, hence promoting tumorigenesis.
Hongxia Ma +8 more
doaj +1 more source
The obstetrical dilemma hypothesis: there's life in the old dog yet
Biological Reviews, Volume 96, Issue 5, Page 2031-2057, October 2021., 2021 ABSTRACT The term ‘obstetrical dilemma’ was coined by Washburn in 1960 to describe the trade‐off between selection for a larger birth canal, permitting successful passage of a big‐brained human neonate, and the smaller pelvic dimensions required for bipedal locomotion. His suggested solution to these antagonistic pressures was to give birth prematurely,
Martin Haeusler +5 more
wiley +1 more source
Are fathers a good substitute for mothers? Paternal care and growth rates in Shodagor children
Developmental Psychobiology, Volume 63, Issue 6, September 2021., 2021 Abstract Biparental care is a hallmark of human social organization, though paternal investment varies between and within societies. The facultative nature of paternal care in humans suggests males should invest when their care improves child survival and/or quality, though testing this prediction can be challenging because of the difficulties of ...
K. E. Starkweather +5 more
wiley +1 more source
Journal of Oncology, Volume 2021, Issue 1, 2021., 2021 Increasing evidence has shown that overexpression of P‐element‐induced wimpy‐testis (PIWI)‐like protein 1 (PIWIL1) was associated with unfavorable prognosis of patients with various types of cancers. Herein, we conducted this meta‐analysis to identify the clinicopathological and prognostic value of the PIWIL1 expression in cancers.
Kehua Jiang +7 more
wiley +1 more source
HIWI is associated with prognosis in patients with hepatocellular carcinoma after curative resection [PDF]
Cancer, 2011 AbstractBACKGROUND:PIWI protein family was found to play an important role in stem cell self‐renewal. Overexpression of HIWI, the human homolog of PIWI family proteins, was found in several solid tumors, although the role of HIWI in hepatocellular carcinoma (HCC) and its prognostic value remain unclear.METHODS:HIWI expression was measured in stepwise ...
Yi-Ming, Zhao +10 more
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PIWI expression and function in cancer
Frontiers in Genetics, 2012 PIWI proteins, a subclade of the Argonaute family proteins, are expressed predominantly in the germline and bind to PIWI-interacting RNAs (piRNAs), which are 25-31 nucleotides in length. The PIWI/piRNA pathway plays critical roles in germline development
Ryusuke eSuzuki +2 more
doaj +1 more source
Direct Differentiation of Human Pluripotent Stem Cells into Haploid Spermatogenic Cells
Cell Reports, 2012 Human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) have been shown to differentiate into primordial germ cells (PGCs) but not into spermatogonia, haploid spermatocytes, or spermatids.
Charles A. Easley, IV +10 more
doaj +1 more source
The role of HIWI in stem cell maintenance and sarcomagenesis.
Journal of Clinical Oncology, 2011 e20500 Background: PIWI proteins comprise a highly conserved protein family that promote genomic integrity during early development via small RNA-mediated gene silencing and DNA methylation-mediate...
S. Siddiqi, M. Terry, I. Matushansky
openaire +2 more sources
Angewandte Chemie, Volume 137, Issue 46, November 10, 2025.Accidentally reversing the lanthanide‐binding sequences of lanmodulin‐inspired short peptides lead to the serendipitous discovery of a set of peptides with a one order of magnitude higher lanthanide‐binding affinity than the uncapped peptides synthesised in the correct direction.
Sophie M. Gutenthaler‐Tietze +5 more
wiley +2 more sources