Results 21 to 30 of about 1,065 (135)
Reconstructing prehistoric demography: What role for extant hunter‐gatherers?
Abstract Demography is central to biological, behavioral, and cultural evolution. Knowledge of the demography of prehistoric populations of both Homo sapiens and earlier members of the genus Homo is, therefore, key to the study of human evolution.
Abigail E. Page, Jennifer C. French
wiley +1 more source
Accidentally reversing the lanthanide‐binding sequences of lanmodulin‐inspired short peptides lead to the serendipitous discovery of a set of peptides with a one order of magnitude higher lanthanide‐binding affinity than the uncapped peptides synthesised in the correct direction.
Sophie M. Gutenthaler‐Tietze +5 more
wiley +2 more sources
Direct Differentiation of Human Pluripotent Stem Cells into Haploid Spermatogenic Cells
Human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) have been shown to differentiate into primordial germ cells (PGCs) but not into spermatogonia, haploid spermatocytes, or spermatids.
Charles A. Easley, IV +10 more
doaj +1 more source
Genetic disorders and male infertility
Abstract Background At present, one out of six couples is infertile, and in 50% of cases, infertility is attributed to male infertility factors. Genetic abnormalities are found in 10%‐20% of patients showing severe spermatogenesis disorders, including non‐obstructive azoospermia.
Shinnosuke Kuroda +6 more
wiley +1 more source
The role of HIWI in stem cell maintenance and sarcomagenesis.
e20500 Background: PIWI proteins comprise a highly conserved protein family that promote genomic integrity during early development via small RNA-mediated gene silencing and DNA methylation-mediate...
S. Siddiqi, M. Terry, I. Matushansky
openaire +2 more sources
Common genetic polymorphisms of microRNA biogenesis pathway genes and breast cancer survival
Background Although the role of microRNA’s (miRNA’s) biogenesis pathway genes in cancer development and progression has been well established, the association between genetic variants of this pathway genes and breast cancer survival is still unknown ...
Sung Hyuna +10 more
doaj +1 more source
Summary Background Realistic and accessible models are essential for training physicians in clinical procedures. This study investigated whether a cost‐effective 3D‐printed skin model is superior to fruit and foam models for teaching skin biopsies. Patients and Methods The study (10/2023‐02/2025) involved 148 medical students who compared the 3D skin ...
Sandra Schuh +5 more
wiley +1 more source
Zusammenfassung Hintergrund Realistische Trainingsmodelle sind essenziell, um Ärztinnen und Ärzte in klinischen Prozeduren zu schulen. In dieser Studie wurde untersucht, ob ein kostengünstiges, selbst generiertes 3D‐gedrucktes Hautmodell Früchten und Schaumstoffmodellen beim Erlernen von Hautstanzen überlegen ist.
Sandra Schuh +5 more
wiley +1 more source
Expression of hiwi gene in human gastric cancer was associated with proliferation of cancer cells [PDF]
AbstractStem cell genetics research may be critical to our understanding of carcinogenesis, as both stem cells and cancer cells possess the ability to self‐renew. Recent discoveries have indicated that the piwi family of genes plays an essential role in stem cell self‐renewal in diverse organisms.
Xiaoying, Liu +10 more
openaire +2 more sources
ABSTRACT Objectives The grandmother hypothesis proposes that ancestral women ceased reproduction midlife to instead provision their grandchildren. An alternative “two‐sex” account proposes that the high energetic burden of caring for slow‐developing offspring was met with biparental investment.
Edward H. Hagen
wiley +1 more source

