Results 1 to 10 of about 1,015 (101)
Relationship between the Occurrence of Genetic Variants of Single Nucleotide Polymorphism in microRNA Processing Genes and the Risk of Developing Multiple Sclerosis [PDF]
Biomedicines, 2022 Multiple sclerosis (MS) is an autoimmune demyelinating disorder of the central nervous system (CNS), which leads to disturbances in the conduction of nerve impulses, cognitive impairment, sensory and motor disturbances, as well as depressive symptoms. MS
Justyna Basak +3 more
doaj +2 more sources
Hiwi Mediated Tumorigenesis Is Associated with DNA Hypermethylation [PDF]
PLoS ONE, 2012 Expression of Piwi proteins is confined to early development and stem cells during which they suppress transposon migration via DNA methylation to ensure genomic stability. Piwi's genomic protective function conflicts with reports that its human ortholog,
Igor Matushansky
exaly +2 more sources
MEIS1 promotes expression of stem cell markers in esophageal squamous cell carcinoma [PDF]
BMC Cancer, 2020 Background MEIS1 (Myeloid ecotropic viral integration site 1) as a homeobox (HOX) transcription factor plays regulatory roles in a variety of cellular processes including development, differentiation, survival, apoptosis and hematopoiesis, as well as ...
Selma Zargari +3 more
doaj +2 more sources
Comparative Binding Studies of the Chelators Methylolanthanin and Rhodopetrobactin B to Lanthanides and Ferric Iron. [PDF]
ChembiochemThe synthesis and the investigation of the lanthanide (Ln) and Fe‐binding properties of the putative lanthanophore methylolanthanin (MLL) and the siderophore rhodopetrobactin B (RPB B) are reported. While both chelators bind Lns, they unexpectedly precipitate with Lns under biologically relevant conditions and thereby challenge the proposed classic ...
Gutenthaler-Tietze SM +9 more
europepmc +2 more sources
BMC Cancer, 2009 Background HIWI, the human homologue of Piwi family, is present in CD34+ hematopoietic stem cells and germ cells, but not in well-differentiated cell populations, indicating that HIWI may play an impotent role in determining or maintaining stemness of ...
Zhihui Wang +2 more
exaly +3 more sources
HTS Teologiese Studies/Theological Studies, 2021 The biblical story on the miracle of the manna in the Sinai Desert aroused many discussions and interpretations over the generations. The current study focuses on Ibn Ezra’s controversy with Hiwi al-Balkhi on the question of whether the manna was a ...
Abraham O. Shemesh
doaj +1 more source
Egyptian Journal of Medical Human Genetics, 2022 Background SALL4 and HIWI are involved in the maintenance of self-renewal capacity of stem cells. Several scrutinizes have demonstrated that SALL4 and HIWI play a key role in cancer development.
Mohammad Mahdi Forghanifard +1 more
doaj +1 more source
Piwi genes are dispensable for normal hematopoiesis in mice. [PDF]
PLoS ONE, 2013 Hematopoietic stem cells (HSC) must engage in a life-long balance between self-renewal and differentiation to sustain hematopoiesis. The highly conserved PIWI protein family regulates proliferative states of stem cells and their progeny in diverse ...
Mona J Nolde +3 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 P-element-induced wimpy testis (PIWI)-interacting RNAs (piRNAs) are a class of small non-coding RNA molecules that are 24–31 nucleotides in length. PiRNAs are thought to bind to PIWI proteins (PIWL1-4, a subfamily of Argonaute proteins), forming piRNA ...
Peixin Dong +8 more
doaj +1 more source
Estimating fertility using adults: A method for under‐enumerated pre‐adult skeletal samples
American Journal of Biological Anthropology, Volume 181, Issue 2, Page 262-270, June 2023., 2023 Abstract Objectives Infant underrepresentation poses a great risk to accurate palaeodemographic findings when analyzing skeletal samples. Empirically derived palaeodemographic methods all require unbiased or minimally biased pre‐adult representation for estimating demographic characteristics, including fertility.
Bonnie R. Taylor +2 more
wiley +1 more source