Results 201 to 210 of about 206,002 (249)

Identification of HLA-B27-Restricted Peptides from the Chlamydia trachomatis Proteome with Possible Relevance to HLA-B27-Associated Diseases

open access: bronze, 2001
Wolfgang Kuon   +13 more
openalex   +1 more source

HLA-B27 and Bacteria

Clinical Rheumatology, 1996
Most HLA-B27 positive individuals live without noticing the risk factor they carry. Only when certain bacteria come into play, usually in the form of intestinal or genital infection, some of the HLA-B27 positive individuals will develop a reactive disease.
P. Toivanen, J. Uksila
openaire   +3 more sources

HLA-B27 polymorphism

Joint Bone Spine, 2001
HLA-B27 is a serologic specificity that encompasses 25 different alleles that encode 23 different products (proteins): HLA-B*2701 to B*2723. These alleles are also called subtypes of HLA-B27, and they may have evolved from the most widespread subtype, B*2705.
Edward J. Ball, Muhammad Asim Khan
openaire   +3 more sources

The Pathogenesis of HLA-B27 Arthritis: Role of HLA-B27 in Bacterial Defense

The American Journal of the Medical Sciences, 1998
The way in which a host accommodates invasive facultative intracellular bacteria must be the key to the development of reactive arthritis. Investigators have analyzed the bacterial events at several levels: invasion into host cells, intracellular survival, translocation from the sites of infection to the joints, residence in the joints, and evasion of ...
Makoto Ikeda, David T. Y. Yu
openaire   +3 more sources

HLA‐B27 and the pathogenesis of spondyloarthritis

Tissue Antigens, 2002
Abstract: The association of HLA‐B27 with ankylosing spondylitis and other spondyloarthropathies ranks among the strongest between any HLA antigen and a human disease. Yet, in spite of intense research and advanced knowledge of the biochemistry and biology of major histocompatibility complex molecules, the mechanism of this association remains unknown.
J A López de Castro, M. Ramos
openaire   +3 more sources

Non-HLA-B27 Genetic Factors in HLA-B27 Associated Diseases [PDF]

open access: possibleClinical Rheumatology, 1996
Family and twin studies showed that besides HLA-B27 other genetic factors are of significance for the pathogenesis of ankylosing spondylitis, reactive arthritis or acute anterior uveitis. There are up to now no strong indications that any subtype of B27 is especially associated with these diseases.
openaire   +2 more sources

Dysfunction of HLA-B27

Scandinavian Journal of Rheumatology, 1990
Every HLA antigen, as defined by the WHO-HLA Nomenclature, is unique. The major function of these molecules is to present antigen-peptides to the T-cell receptor, thereby contributing to the immunological defence mechanism. This function is regulated for each MHC antigen by its unique structure, with the peptide-binding pockets of the three-dimensional
openaire   +3 more sources

HLA-B27 Typing

Annals of Internal Medicine, 1980
Excerpt To the editor: It is unfortunate that Dr. Calin detracts from his many excellent contributions on the importance of the HLA system in rheumatic disease (1) by concluding his recent article,...
openaire   +3 more sources

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