Results 71 to 80 of about 93,215 (258)
Molecular & Cellular Proteomics, 2016 Expression of HLA-B27 is strongly associated with ankylosing spondylitis (AS) and other spondyloarthropathies. While this is true for the majority of HLA-B27 allotypes, HLA-B*27:06 and HLA-B*27:09 are not associated with AS.
R. Schittenhelm +4 more
semanticscholar +1 more source
Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance
Advanced Science, EarlyView.Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai +5 more
wiley +1 more source
Clinical and MRI responses to etanercept in early non-radiographic axial spondyloarthritis : 48-week results from the EMBARK study [PDF]
, 2015 Objective: To evaluate the efficacy and safety of etanercept (ETN) after 48 weeks in patients with early active non-radiographic axial spondyloarthritis (nr-axSpA).
Bonin, Randi +15 more
core +1 more source
Clonal sharing of CD8+ T‐cells links skin and joint inflammation in psoriatic arthritis
Arthritis &Rheumatology, Accepted Article.Objective Psoriatic arthritis (PsA) is an HLA class I‐associated inflammatory arthritis that develops in up to 30% of people with psoriasis. We tested the hypothesis that skin and joint inflammation in PsA is linked in terms of CD8+ T‐cell phenotype and clonality.
Lucy E. Durham +14 more
wiley +1 more source
Histocompatibility HLA class I in anterior uveitis patients with and without spondyloarthritis
Современная ревматология, 2018 Anterior uveitis (AU) and ankylosing spondylitis (AS) are associated with histocompatibility human leukocyte antigen (HLA)-B27. Previous genetic studies conducted in different populations have also demonstrated other genetic associations, including HLA ...
I. A. Guseva +2 more
doaj +1 more source
Saudi Journal for Health Sciences, 2021 Background: Reactive arthritis (RA), apart from presenting as an immune reaction to certain microorganisms, had also shown to have a genetic predisposition. Human leukocyte antigen (HLA-B27) is an allele of the HLA Class I molecules and its positivity in
Jeshyca Shougrakpam +3 more
doaj +1 more source
Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis [PDF]
, 2017 Background: Dysbiosis has been recently demonstrated in patients with ankylosing spondylitis (AS) but its implications in the modulation of intestinal immune responses have never been studied.
Alessandro, Riccardo +13 more
core +2 more sources
Autoantibody response towards chromatin in patients with juvenile idiopathic arthritis
Arthritis &Rheumatology, Accepted Article.Objective Juvenile idiopathic arthritis (JIA) patients frequently exhibit antinuclear antibodies (ANAs), but the specific antigen target recognized by them and the presence of additional autoantibody specificities in JIA patients remains elusive. Methods Plasma samples from 110 untreated patients with active JIA, as well as from 14 children with ...
Viola Pitkänen +13 more
wiley +1 more source
International Journal of Cancer, EarlyView.What's New? The anti‐aging protein klotho (KL) is a potential tumor suppressor and prognostic marker in glioblastoma. Little is known, however, about its mechanism of action and clinical relevance. This study examined KL expression in the setting of persistent inflammation and other stressors, including radiotherapy.
Andrea Galluzzo +19 more
wiley +1 more source
Arthritis Research & Therapy, 2021 Background To investigate the efficacy of secukinumab in patients with active non-radiographic axial spondyloarthritis (nr-axSpA) grouped by disease activity as assessed by C-reactive protein (CRP) levels and/or magnetic resonance imaging (MRI) scores ...
Jürgen Braun +14 more
doaj +1 more source