Results 91 to 100 of about 101,671 (163)

High-throughput high-resolution class I HLA genotyping in East Africa. [PDF]

open access: yes, 2010
HLA, the most genetically diverse loci in the human genome, play a crucial role in host-pathogen interaction by mediating innate and adaptive cellular immune responses. A vast number of infectious diseases affect East Africa, including HIV/AIDS, malaria,
Leonard Maboko   +53 more
core   +1 more source

Allogeneic Hematopoietic Stem Cell Transplant recipients in Spain: Human Leucocyte Antigen characteristics and diversity by high-resolution analysis

open access: yes
There are many studies on the polymorphism of the HLA system in healthy donor populations, such as registries of unrelated bone marrow donors. Investigations on the characterization of the HLA complex in hematopoietic stem cell transplant (HSCT) patients,
Solano Vercet, Carlos   +3 more
core   +1 more source

HLA-B51 ALLELE CORRELATION WITH AUTOIMMUNE DISEASES OTHER THAN BEHÇET’S: A RETROSPECTIVE ANALYSIS

open access: yes, 2018
Behçet’s Disease (BD) is a systemic vasculitis, prevalent in males, with a chronic and inflammatorycourse and with multi-organ involvement. Are affected young subjects (20-30 years).
SANGERMANO, A.   +8 more
core   +1 more source

Peptide motifs of HLA-B51, -B52 and -B78 molecules, and implications for Behcet's disease

open access: yes, 1995
Here we report peptide motifs of five HLA-B molecules, B*5101, B*5102, B*5103 B*5201 and B*7801. Motifs were obtained by pool sequencing of natural ligands eluted from the respective molecules expressed in C1R cells upon transfection.
Roetzschke, O.   +6 more
core   +1 more source

Cerebral Aneurysms: A Rare Feature of Behçet's Disease—A Case Report and Review of the Literature

open access: yesCase Reports in Neurological Medicine, 2013
Behçet's disease (BD) is a multisystem vascular inflammatory disease with several clinical manifestations. Intracranial aneurysms are an extremely rare but nevertheless severe complication of BD. We report a case of a 44-year-old man. The diagnosis of BD
Samia Younes   +8 more
doaj   +1 more source

Identification of a novel HLA-C*08 allele, HLA-C*08:01:20

open access: yes, 2017
HLA-C*08:01:20 differs from C*08:01:01 by a single nucleotide substitution at position 93 of exon 2.SCI(E)EDITORIAL MATERIAL3178 ...
D. Li   +7 more
core   +1 more source

Unique features of HLA-mediated HIV evolution in a Mexican cohort: a comparative study

open access: yes, 2009
Background: Mounting evidence indicates that HLA-mediated HIV evolution follows highly stereotypic pathways that result in HLA-associated footprints in HIV at the population level.
Santiago Avila-Rios   +38 more
core   +1 more source

HLA and Eye Inflammation in Behçet\'s Syndrome [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences
Behçet's disease (BD) is a chronic multisystem inflammatory disorder characterized mainly by recurrent oral ulcers, ocular involvement, genital ulcers, and skin lesions, presenting with remissions and exacerbations.
Zahra Hoseini, Saeid Abediankenari
doaj  

Coexistence of ankylosing spondylitis and Behçet's disease: Successful treatment with upadacitinib

open access: yesImmunity, Inflammation and Disease
Background Ankylosing spondylitis (AS) and Behçet's disease (BD) are distinct inflammatory disorders, but their coexistence is a rare clinical entity. This case sheds light on managing this complex scenario with Janus kinase (JAK) inhibitors.
Krasimir Kraev   +9 more
doaj   +1 more source

The absence of disease-specific polymorphisms within the HLA-B51 gene that is the susceptible locus for Behcet's disease

open access: yes, 2001
Behçet's disease is known to be associated with HLA-B51 in many different populations. Genetic evidence supports that the susceptible gene for Behçet's disease is the HLA-B51 allele at the HLA-B locus.
Shiina, T.   +7 more
core  

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