Results 91 to 100 of about 101,671 (163)
High-throughput high-resolution class I HLA genotyping in East Africa. [PDF]
HLA, the most genetically diverse loci in the human genome, play a crucial role in host-pathogen interaction by mediating innate and adaptive cellular immune responses. A vast number of infectious diseases affect East Africa, including HIV/AIDS, malaria,
Leonard Maboko +53 more
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There are many studies on the polymorphism of the HLA system in healthy donor populations, such as registries of unrelated bone marrow donors. Investigations on the characterization of the HLA complex in hematopoietic stem cell transplant (HSCT) patients,
Solano Vercet, Carlos +3 more
core +1 more source
HLA-B51 ALLELE CORRELATION WITH AUTOIMMUNE DISEASES OTHER THAN BEHÇET’S: A RETROSPECTIVE ANALYSIS
Behçet’s Disease (BD) is a systemic vasculitis, prevalent in males, with a chronic and inflammatorycourse and with multi-organ involvement. Are affected young subjects (20-30 years).
SANGERMANO, A. +8 more
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Peptide motifs of HLA-B51, -B52 and -B78 molecules, and implications for Behcet's disease
Here we report peptide motifs of five HLA-B molecules, B*5101, B*5102, B*5103 B*5201 and B*7801. Motifs were obtained by pool sequencing of natural ligands eluted from the respective molecules expressed in C1R cells upon transfection.
Roetzschke, O. +6 more
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Cerebral Aneurysms: A Rare Feature of Behçet's Disease—A Case Report and Review of the Literature
Behçet's disease (BD) is a multisystem vascular inflammatory disease with several clinical manifestations. Intracranial aneurysms are an extremely rare but nevertheless severe complication of BD. We report a case of a 44-year-old man. The diagnosis of BD
Samia Younes +8 more
doaj +1 more source
Identification of a novel HLA-C*08 allele, HLA-C*08:01:20
HLA-C*08:01:20 differs from C*08:01:01 by a single nucleotide substitution at position 93 of exon 2.SCI(E)EDITORIAL MATERIAL3178 ...
D. Li +7 more
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Unique features of HLA-mediated HIV evolution in a Mexican cohort: a comparative study
Background: Mounting evidence indicates that HLA-mediated HIV evolution follows highly stereotypic pathways that result in HLA-associated footprints in HIV at the population level.
Santiago Avila-Rios +38 more
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HLA and Eye Inflammation in Behçet\'s Syndrome [PDF]
Behçet's disease (BD) is a chronic multisystem inflammatory disorder characterized mainly by recurrent oral ulcers, ocular involvement, genital ulcers, and skin lesions, presenting with remissions and exacerbations.
Zahra Hoseini, Saeid Abediankenari
doaj
Coexistence of ankylosing spondylitis and Behçet's disease: Successful treatment with upadacitinib
Background Ankylosing spondylitis (AS) and Behçet's disease (BD) are distinct inflammatory disorders, but their coexistence is a rare clinical entity. This case sheds light on managing this complex scenario with Janus kinase (JAK) inhibitors.
Krasimir Kraev +9 more
doaj +1 more source
Behçet's disease is known to be associated with HLA-B51 in many different populations. Genetic evidence supports that the susceptible gene for Behçet's disease is the HLA-B51 allele at the HLA-B locus.
Shiina, T. +7 more
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