Results 101 to 110 of about 101,671 (163)

Replication of the association of HLA-B7 with Alzheimer's disease: a role for homozygosity?

, 2006
Background: There are reasons to expect an association with Alzheimer's disease (AD) within the HLA region. The HLA-B & C genes have, however, been relatively understudied.
Smith, AD, Horton Roger, Barnardo Martin CNM, Stephan Beck, Warden Donald R, Warden, DR, Martin CNM Barnardo, Barnetson, L, Smith A David, Andrew Sutherland, Lehmann, DJ, Beck Stephan, Barnardo, MC, Isabel Quiroga, Fuggle Susan, Barnetson Lin, Barnardo, MCNM, Quiroga Isabel, Lehmann Donald J, Roger Horton, Beck, S, Susan Fuggle, Donald R Warden, Fuggle, S, Sutherland Andrew, Sutherland, A, Donald J Lehmann, Lin Barnetson, A David Smith, Quiroga, I, Horton, R   +30 more
core   +1 more source

The HLA-DRA*0102 allele: correct nucleotide sequence and associated HLA haplotypes

, 2002
Here we correct the nucleotide sequence of a single known variant of the HLA-DRA gene. We show that the coding regions of the HLA-DRA*0101 and HLA-DRA*0102 alleles do not differ at two codons as reported previously, but only in codon 217.
Marsh, SGE, Marsh, S. G., Kralovicova, J, Hammarstrom, L, Kralovicova, J., Hammarstrom, L., Vorechovsky, I, Waller, M. J., Vorechovsky, I., Waller, MJ   +9 more
core   +1 more source

Discovery of the HLA-DQB1*06:465 allele, a variant of HLA-DQB1*06:04:01:01

HLA-DQB1*06:465 differs from HLA-DQB1*06:04:01:01 by a non-synonymous nucleotide substitution in codon ...
John Jeongseok Yang, Heung-Bum Oh
core   +1 more source

Allodeterminants and evolution of a novel HLA-B5 CREG antigen, HLA-B SNA

, 1990
A novel HLA-B5 CREG gene, HLA-B SNA was cloned and the primary structure was determined. The sequence data showed that HLA-B SNA was identical to HLA-B51 except the α1 domain in which one amino acid substitution at residue 74 and 5 amino acid ...
Sekimata, Masayuki, Kano, Kyoichi, Hiraiwa, Masaki, Andrien, Marc, Takiguchi, Masafumi, Karaki, Sachiko, Yamamoto, Junji, Dupont, Etienne   +7 more
core  

The role of HLA-B27 in inflammatory arthritis

, 2009
Redacted electronic version excludes material for which permission has not been granted by the rights holderThe MHC class I allele, HLA-B27, is strongly associated with a group of inflammatory arthritic conditions collectively known as ...
Lynch, Sarah Janice
core  

Contributions of vitamin D response elements and HLA promoters to multiple sclerosis risk

, 2012
Objective: The identification of a vitamin D-responsive (VDRE) motif within the HLA-DRB1*15:01 promoter region provides an attractive explanation for the combined effects of HLA-DR inheritance and vitamin D exposure on multiple sclerosis (MS) risk.
Qiu, W., Nolan, D., Kermode, A., Tschochner, M., Mastaglia, F., Christiansen, F.T., Witt, C., Castley, A., James, I., Sayer, D., Carroll, W.   +10 more
core  

Characterisation of HLA-specific antibodies [PDF]

A successful kidney transplant is the best treatment for established renal failure, yet around 300 patients per annum are denied transplants because they have antibodies, most notably directed against donor HLA or ABO in their blood, which have the ...
Lowe, David Philip
core  

HLA Antigen Profile Differences in Patients with SCC (Squamous Cell Carcinoma) In-Situ /Actinic Keratosis and Invasive SCC: Is There a Genetic Succeptibility for Invasive SCC Development?

Eurasian Journal of Medicine, 2019
Objective: Actinic keratoses (AK) are proliferation of neoplastic keratinocytes confined to the epidermis induced by damaging solar ultraviolet radiation (UVR).
Mustafa Atasoy, Rana Anadolu-Braise, Ibrahim Pirim, Hasan Dogan, Mevlüt Ikbal   +4 more
doaj  

HLA high performance and real-time simulation studies with CERTI [PDF]

, 2011
Our work takes place in the context of the HLA standard and its application in real-time systems context. Indeed, current HLA standard is inadequate for taking into consideration the different constraints involved in real-time computer systems.
Adelantado, Martin, Noulard, Eric, Chaudron, Jean-Baptiste, Siron, Pierre   +3 more
core  

Clinical phenotypes of Korean patients with Behcet disease according to gender, age at onset, and HLA-B51. [PDF]

Korean J Intern Med, 2018
Ryu HJ, Seo MR, Choi HJ, Baek HJ.
europepmc   +1 more source