Results 111 to 120 of about 144,091 (315)

Frecuencia fenotípica y génica de los antígenos HLA en una muestra de la población cubana Phenotypic and genic frequency of HLA antigens in a sample of the Cuban population

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2005
Se realizó un estudio de la frecuencia fenotípica y génica de los antígenos del sistema principal de histocompatibilidad HLA en personas no relacionadas, supuestamente sanas, tomadas como muestra de la población cubana.
Luz M Morera Barrios, Catalino R, Ustáriz García, María A. García García, Nelioska Díaz Báez, Rosa M Lam Díaz, Ana M Guerreiro Hernández, Porfirio Hernández Ramírez, José M Ballester Santovenia   +8 more
doaj  

High sensitivity of human leukocyte antigen–B*5701 as a marker for immunologically confirmed abacavir hypersensitivity in white and black patients

, 2008
Background. Although the human leukocyte antigen (HLA)-B*5701 is highly associated with a hypersensitivity reaction (HSR) to abacavir (ABC), variable sensitivities have been reported when clinical data alone have been used to define an ABC HSR.
Stancil, B., Balu, R., Mosteller, M., Wannamaker, P., Phillips, E.J., Saag, M., Burman, W., Brothers, C., Brachman, P., Hughes, A., Sutherland‐Phillips, D., Martorell, C., Mallal, S., Shaefer, M.   +13 more
core  

Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection

, 2006
Cellular immune responses are an important correlate of hepatitis C virus (HCV) infection outcome. These responses are governed by the host's human leukocyte antigen (HLA) type, and HLA-restricted viral escape mutants are a critical aspect of this host ...
Cheng, Wendy, Battegay, Manuel, E. Freitas, Weber, R., Furrer, H., Jeffrey, G., James, Ian, Park, Lawrence P, Swiss HIV Cohort Study,, G. Jeffrey, Battegay, M., Jeffrey, Gary, Herrmann, S., James, I., Weber, R., Battegay, M., Chapman, R., S. Herrmann, Furrer, Hansjakob, Telenti, Amalio, Freitas, E., Telenti, A., Lucas, M., M. Lucas, null null, I. James, Weber, Rainer, Telenti, A., Lucas, M., Freitas, Elizabeth, H. Furrer, Cheng, W., Jeffrey, G., Gaudieri, S., S. A. Mallal, Park, P., Freitas, E., Cheng, W., K. Pfafferott, Pfafferott, K., S. Gaudieri, R. Weber, Naidoo, Kiloshni, A. Rauch, Pfafferott, K., Mallal, Simon A, L. P. Park, Rauch, A., Chapman, R., A. Telenti, Pfafferott, Katja, R. Chapman, Lucas, Michaela, M. Battegay, Park, L.P., Naidoo, K., Herrmann, Susan, K. Naidoo, Furrer, H., Rauch, Andri, Park, L. P., W. Cheng, Herrmann, S., Naidoo, K., Chapman, Russell, Rauch, A., Mallal, S.A., Gaudieri, S., Mallal, S. A., James, I., Gaudieri, Silvana   +70 more
core   +1 more source

Dordaviprone Maintenance After Allogeneic HCT for High‐Risk Acute Myeloid Leukemia and Myelodysplastic Neoplasm

American Journal of Hematology, EarlyView.
ABSTRACT Dordaviprone is a first‐in‐class small‐molecule imipridone. In preclinical studies, it is active against leukemia cells harboring a TP53 mutation or complex karyotype and leukemia stem cells while sparing normal bone marrow cells. This study aimed to determine the safety of dordaviprone maintenance after allogeneic hematopoietic cell ...
Vijaya Raj Bhatt, Christopher S. Wichman, Alyssa Bouska, Moataz Ellithi, Michael Haddadin, Javeed Iqbal, James E. Talmadge, Lori J. Maness, Krishna Gundabolu   +8 more
wiley   +1 more source

Gemcitabine alters the proteasome composition and immunopeptidome of tumour cells

OncoImmunology, 2018
The antigenic makeup of tumour cells can have a profound effect on the progression of cancer and success of immunotherapies. Therefore, one strategy to improve the efficacy of cancer treatments is to augment the antigens displayed by tumours. The present
A. M. Gravett, N. Trautwein, S. Stevanović, A. G. Dalgleish, J. Copier   +4 more
doaj   +1 more source

Studies on polymorphic alu insertions and genomic diversity within the major histocompatibility complex

, 2005
After the initiation of the human genome sequencing project and the introduction of the field of 'bioinformatics', interest in human genetic diversity studies has been increased.
Dunn, David Suliman
core  

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Analysis of Human Leukocyte Antigen Frequency among Renal Transplant Recipients and Donors in Nepal

Global Journal of Transfusion Medicine
Background and Objectives: Kidney transplants are effective for advanced renal failure, but graft rejection can occur when the recipient’s immune system misidentifies the kidney as a foreign object.
Rekha Manandhar, Gaurab Pandey, Ranjan Raj Bhatta, Runa Jha   +3 more
doaj   +1 more source

HLA-A AND HLA-B ANTIGENS IN CHRONIC-BRONCHITIS

, 1993
The A- and B- types of Human Leucocyte Antigens (HLA) were examined in a group of Greek patients with a diagnosis of chronic bronchitis. The results were compared to those of 400 healthy unrelated controls (smokers and non-smokers) from the same population.
ANAGNOSTOPOULOU, U, TOUMBIS, M, KONSTANTOPOULOS, K, KOTSOVOULOUFOUSKAKI, V, ZERVAS, J   +4 more
openaire   +1 more source

Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection

Animal Models and Experimental Medicine, EarlyView.
Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley   +1 more source