Results 231 to 240 of about 164,764 (309)

High-throughput cloning reveals diverse properties of T-cell receptors targeting minor histocompatibility antigens. [PDF]

open access: yesBlood Adv
Ito S   +16 more
europepmc   +1 more source

Brain Pericytes and Wnt/β‐Catenin Signaling Induce Functional Blood–Brain Barrier Phenotype in Human iPSC‐Derived Model

open access: yesSmall Methods, EarlyView.
This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto   +12 more
wiley   +1 more source

Anterior Uveitis in an HLA-B27 Positive Patient Following Influenza Vaccination. [PDF]

open access: yesInt Med Case Rep J
Pan C   +12 more
europepmc   +1 more source

Plasma Proteomics Analysis Identifying IGFBP2 as a Potential Diagnostic Biomarker for Laryngeal Squamous Cell Carcinoma

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Currently, there are no blood biomarkers available for the early diagnosis of laryngeal squamous cell carcinoma (LSCC). The objective of this study was to search for potential plasma biomarkers for the diagnosis of LSCC. Methods Plasma samples were taken from patients with LSCC and healthy controls for proteomic analysis.
Shuang Teng   +13 more
wiley   +1 more source

Integrating interferon gamma receptor pathways, antigenicity, and immune contexture as predictors of immunotherapeutic strategies for mucosal melanomas. [PDF]

open access: yesJ Immunother Cancer
Monti M   +29 more
europepmc   +1 more source

Towards the Development of a Conceptual Framework of the Determinants of Pre‐eclampsia: A Hierarchical Systematic Review of Biomarkers

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Pre‐eclampsia is a leading cause of maternal and perinatal morbidity and mortality. There are several determinants of individual pregnant women's risk of developing pre‐eclampsia, including biomarkers and ultrasound markers. Objective A conceptual framework to collate and summarise the extensive body of literature on biomarkers ...
Terteel Elawad   +89 more
wiley   +1 more source

Single Cell Analysis Reveals Dynamic Changes of Distinct Cell Populations in Human Nickel Allergy

open access: yesAllergy, EarlyView.
We investigated cell types mediating the early and late inflammatory responses in human Ni2+‐allergy by scRNA‐Seq. Early responsiveness was mainly mediated by TLR4+TAGLN− endothelial cells indirectly activating TLR4−KRT16+ keratinocytes, and CCR7+DCN+ DCs. Late responsiveness was crucially driven by infiltration of KLF2+ central memory T cells and TLR4+
Marc Schmidt   +7 more
wiley   +1 more source

Trispecific targeting of T cells engineered with TCR mimic antibodies to limit antigen escape. [PDF]

open access: yesJ Immunother Cancer
Dao T   +13 more
europepmc   +1 more source

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