Results 171 to 180 of about 125,944 (285)

Signal Transducer and Activator of Transcription (STAT) Proteins Regulate Mucosal‐Associated Invariant T (MAIT) Cell Function

open access: yesImmunology, EarlyView.
Integrated transcriptomic, proteomic and flow cytometry analyses reveal that STAT1 negatively regulates MAIT cell effector and glycolytic functions, while STAT3, STAT5 and HIF1α act as positive modulators. Targeting these pathways may offer new strategies to restore MAIT cell function in immune dysregulation and cancer.
Olivia J. Cheng   +7 more
wiley   +1 more source

CD169<sup>+</sup> and HLA-DR<sup>+</sup> extracellular vesicles are highly represented in human plasma and dynamically expressed in SARS-CoV-2 infection and long COVID-associated sequelae. [PDF]

open access: yesFront Cell Infect Microbiol
Fanelli M   +21 more
europepmc   +1 more source

SAT0024 TRANSCRIPTOMIC PROFILING OF THE MICROENVIRONMENT DRIVEN RE-SHAPING OF PATHOGENIC CIRCULATORY AND SYNOVIAL HLA-DR+ CD4 T SUBSETS IN ACTIVE JUVENILE IDIOPATHIC ARTHRITIC PATIENTS [PDF]

open access: bronze, 2019
Jing Yao Leong   +10 more
openalex   +1 more source

Blood Immunopathology of Tuberculosis Patients Disrupts Monocyte‐Dependent T‐Cell Activation and Cytokine Expression

open access: yesImmunology, EarlyView.
TB serum selectively disrupts monocyte‐dependent PHA T cell activation and cytokines associated with proliferation while preserving SEB T cell and Pam3/PHA monocyte cytokine responses. ABSTRACT Pulmonary tuberculosis in humans is characterised by features of immunopathology, which influence both antimycobacterial therapy and the long‐term prognosis. In
Joseph F. Arthur   +20 more
wiley   +1 more source

Redundancy in Antigen-Presenting Function of the HLA-DR and -DQ Molecules in the Multiple Sclerosis-Associated HLA-DR2 Haplotype

open access: green, 2006
Mireia Sospedra   +10 more
openalex   +2 more sources

Multi‐omics profiling of chronic immune‐mediated skin diseases: SKINERGY protocol and strategic evaluation

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
The SKINERGY study will investigate six immune‐mediated inflammatory skin diseases through a nationwide collaboration across all Dutch university medical centres. Involving 720 patients and 120 healthy volunteers, it is aimed at generating a high‐quality dataset to identify biomarkers that enable personalized treatment strategies and improved disease ...
N. G. Koster   +68 more
wiley   +1 more source

Hepatitis C virus (HCV) in cryoglobulinaemic leukocytoclastic vasculitis (LCV): could the presence of HCV in skin lesions be related to T CD8+ lymphocytes, HLA‐DR and ICAM‐1 expression? [PDF]

open access: bronze, 1999
Elisabetta Bernacchi   +8 more
openalex   +1 more source

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