Results 11 to 20 of about 2,861,094 (164)

HLA-DR receptor density and expression of classical HLA genes.

open access: yes, 2023
Samples were analyzed before surgery (`pre-OP´) as well as on postoperative days one (`POD1´) and seven (`POD7´). (A) Surface expression of HLA-DR on CD14+-monocytes (****p+-monocytes was used for reverse transcription and subsequent qPCR experiments ...
Judith Schenz (5467220)   +6 more
core   +1 more source

A distinct subset of human NK cells expressing HLA-DR expand in response to IL-2 and can aid immune responses to BCG. [PDF]

open access: yes, 2011
Subsets of NK cells can have distinct functions. Here, we report that >25% of human peripheral blood NK cells express HLA-DR after culture with IL-2.
Emma L. Wise   +18 more
core   +1 more source

Replication of the association of HLA-B7 with Alzheimer's disease: a role for homozygosity? [PDF]

open access: yes, 2006
Background: There are reasons to expect an association with Alzheimer's disease (AD) within the HLA region. The HLA-B & C genes have, however, been relatively understudied.
Smith, AD   +30 more
core   +1 more source

Genetic and serological heterogeneity of the supertypic HLA-B locus specificities Bw4 and Bw6 [PDF]

open access: yes, 1989
Gene cloning and sequencing of the HLA-B locus split antigens B38 (B16.1) and B39 (B16.2) allowed localization of their subtypic as well as their public specificities HLA-Bw4 or -Bw6 to the c~-helical region of the c~ 1 domain flanked by the amino acid ...
Gekeler, V.   +5 more
core   +1 more source

The effect of interleukin-10 and transforming growth factor β-1 on HLA-DR expression in colonic epithelial cells

open access: yesMediators of Inflammation, 1998
The aim of this study was to assess whether interleukin-10 (IL-10) and/or transforming growth factor β-1 (TGF β1) downregulate HLA-DR expression using the HT29 cell line as a model of colonic epithelial cells.
M. J. Zimmerman   +2 more
doaj   +1 more source

Generation of functional HLA-DR*1101 tetramers receptive for loading with pathogen or tumour derived synthetic peptides

open access: yesBMC Immunology, 2005
Background MHC class I-peptide tetramers are currently utilised to characterize CD8+ T cell responses at single cell level. The generation and use of MHC class II tetramers to study antigen-specific CD4+ T cells appears less straightforward.
Protti Maria   +9 more
doaj   +1 more source

Allelic variation in HLA-B and HLA-C sequences and the evolution of the HLA-B alleles [PDF]

open access: yes, 1989
Several new HLA-B (B8, B51, Bw62)- and HLA-C (Cw6, Cw7)-specific genes were isolated either as genomic cosmid or cDNA clones to study the diversity of HLA antigens.
Tabaczewski, P.   +9 more
core   +1 more source

Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by D94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis [PDF]

open access: yes, 1998
Human histocompatibility leukocyte antigen (HLA)-E is a nonclassical HLA class I molecule, the gene for which is transcribed in most tissues. It has recently been reported that this molecule binds peptides derived from the signal sequence of HLA class I ...
John E. Coligan   +14 more
core   +1 more source

HLA-A, HLA-B and HLA-DR matching reduces the rate of corneal allograft [PDF]

open access: yes, 2005
Titelblatt, Widmung, Abkürzungs- und Phrasenverzeichnis, Inhaltsverzeichnis 1\. Einleitung 2\. Methoden 3\. Ergebnisse 4\. Diskussion 5\. Zusammenfassung 6\.
Khaireddin, Riad
core   +1 more source

The role of HLA-B27 in inflammatory arthritis [PDF]

open access: yes, 2009
Redacted electronic version excludes material for which permission has not been granted by the rights holderThe MHC class I allele, HLA-B27, is strongly associated with a group of inflammatory arthritic conditions collectively known as ...
Lynch, Sarah Janice
core   +2 more sources

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