HLA-DR receptor density and expression of classical HLA genes.
Samples were analyzed before surgery (`pre-OP´) as well as on postoperative days one (`POD1´) and seven (`POD7´). (A) Surface expression of HLA-DR on CD14+-monocytes (****p+-monocytes was used for reverse transcription and subsequent qPCR experiments ...
Judith Schenz (5467220) +6 more
core +1 more source
A distinct subset of human NK cells expressing HLA-DR expand in response to IL-2 and can aid immune responses to BCG. [PDF]
Subsets of NK cells can have distinct functions. Here, we report that >25% of human peripheral blood NK cells express HLA-DR after culture with IL-2.
Emma L. Wise +18 more
core +1 more source
Replication of the association of HLA-B7 with Alzheimer's disease: a role for homozygosity? [PDF]
Background: There are reasons to expect an association with Alzheimer's disease (AD) within the HLA region. The HLA-B & C genes have, however, been relatively understudied.
Smith, AD +30 more
core +1 more source
Genetic and serological heterogeneity of the supertypic HLA-B locus specificities Bw4 and Bw6 [PDF]
Gene cloning and sequencing of the HLA-B locus split antigens B38 (B16.1) and B39 (B16.2) allowed localization of their subtypic as well as their public specificities HLA-Bw4 or -Bw6 to the c~-helical region of the c~ 1 domain flanked by the amino acid ...
Gekeler, V. +5 more
core +1 more source
The aim of this study was to assess whether interleukin-10 (IL-10) and/or transforming growth factor β-1 (TGF β1) downregulate HLA-DR expression using the HT29 cell line as a model of colonic epithelial cells.
M. J. Zimmerman +2 more
doaj +1 more source
Background MHC class I-peptide tetramers are currently utilised to characterize CD8+ T cell responses at single cell level. The generation and use of MHC class II tetramers to study antigen-specific CD4+ T cells appears less straightforward.
Protti Maria +9 more
doaj +1 more source
Allelic variation in HLA-B and HLA-C sequences and the evolution of the HLA-B alleles [PDF]
Several new HLA-B (B8, B51, Bw62)- and HLA-C (Cw6, Cw7)-specific genes were isolated either as genomic cosmid or cDNA clones to study the diversity of HLA antigens.
Tabaczewski, P. +9 more
core +1 more source
Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by D94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis [PDF]
Human histocompatibility leukocyte antigen (HLA)-E is a nonclassical HLA class I molecule, the gene for which is transcribed in most tissues. It has recently been reported that this molecule binds peptides derived from the signal sequence of HLA class I ...
John E. Coligan +14 more
core +1 more source
HLA-A, HLA-B and HLA-DR matching reduces the rate of corneal allograft [PDF]
Titelblatt, Widmung, Abkürzungs- und Phrasenverzeichnis, Inhaltsverzeichnis 1\. Einleitung 2\. Methoden 3\. Ergebnisse 4\. Diskussion 5\. Zusammenfassung 6\.
Khaireddin, Riad
core +1 more source
The role of HLA-B27 in inflammatory arthritis [PDF]
Redacted electronic version excludes material for which permission has not been granted by the rights holderThe MHC class I allele, HLA-B27, is strongly associated with a group of inflammatory arthritic conditions collectively known as ...
Lynch, Sarah Janice
core +2 more sources

