Results 81 to 90 of about 2,861,094 (164)
Journal of Translational MedicineBackground According to the definition of the International Society for Cell and Gene Therapy (ISCT), mesenchymal stromal cells (MSCs) do not express HLA-DR.
Zyrafete Kuçi +10 more
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Regulatory effects of microRNAs on monocytic HLA-DR surface expression. [PDF]
Decreased monocytic HLA-DR expression is the most studied biomarker of immune competency in critically ill and autoimmune disease patients. However, the underlying regulatory mechanisms remain largely unknown. One probable HLA-DR dysregulation is through
Moolan-Vadackumchery, Robin +8 more
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Frontiers in ImmunologyIntroductionReduced monocyte HLA-DR expression, a hallmark of immunosuppression in sepsis, is associated with infectious complications and mortality. Therapeutic strategies, including IFN-γ, have been used to restore monocyte HLA-DR and immune function ...
Timothy Arthur Chandos Snow +13 more
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HLA-B*5701 screening for hypersensitivity to Abacavir [PDF]
, 2008 Background Hypersensitivity reaction to abacavir is strongly associated with the presence of the HLA-B*5701 allele. This study was designed to establish the effectiveness of prospective HLA-B*5701 screening to prevent the hypersensitivity reaction to ...
Jagel-Guedes, E. +17 more
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Frontiers in ImmunologyIntroductionRheumatoid arthritis (RA) is a systemic autoimmune disease that leads to inflammation of synovial joints and other organs. Many RA patients “share” a common peptide sequence within the HLA-DR (MHC II) molecule expressed on antigen-presenting ...
Christian Geier +5 more
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Characterisation of HLA-specific antibodies [PDF]
A successful kidney transplant is the best treatment for established renal failure, yet around 300 patients per annum are denied transplants because they have antibodies, most notably directed against donor HLA or ABO in their blood, which have the ...
Lowe, David Philip
core
Discovery of the HLA-DQB1*06:465 allele, a variant of HLA-DQB1*06:04:01:01
HLA-DQB1*06:465 differs from HLA-DQB1*06:04:01:01 by a non-synonymous nucleotide substitution in codon ...
John Jeongseok Yang, Heung-Bum Oh
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"Induction of Thymic HLA-DR signaling with Alpha-smooth muscle Actin expression during the second and third trimesters of gestation " [PDF]
Acta Medica Iranica, 2003 Less than 5% of prenatal thymoctes express HLA-DR before week 12 of gestation. However, the number of HLA-DR- positive cells increases during the late second and third trimesters of development. To determine the role of alpha-smooth muscle actin in fetal
Tamiolakis D +5 more
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Oral lichen planus and HLA DR.
Collegium antropologicum, 1998 Oral lichen planus (OLP) is a chronic inflammatory mucocutaneous disease, predominantly seen in middle-aged female patients. Histopathologically, OLP includes parakeratosis with T-lymphocyte subepithelial infiltration. In etiology of OLP, chronically liver and biliary diseases, stress-induced hypertension, inheritance and most commonly carbohydrate ...
Ognjenović, Marina +4 more
openaire +2 more sources
卵巢上皮癌中 HLA-DR 及 HLA-ABC 表达的临床意义
Zhongshan Daxue xuebao. Yixue kexue ban, 2004 【目的】研究卵巢上皮癌(EOC)中HLA-DR及HLA-ABC的表达及其临床意义,为以HLA为靶点的肿瘤免疫治疗提供理论依据。【方法】应用免疫组织化学SP法检测57例卵巢上皮癌、35例卵巢良性上皮肿瘤及20例正常卵巢组织中HLA-DR及HLA-ABC的表达情况。【结果】①卵巢癌HLA-DR阳性率(33/57)显著高于良性肿瘤(4/35)及正常卵巢组织(1/20 ...
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