Human-leukocyte antigen typing in Javanese patients with recurrent aphthous stomatitis
Background: Recurrent aphthous stomatitis (RAS) is a common oral disorder that despite extensive researches, the etiology of this phenomenon is still unknown.
Diah Savitri Ernawati +2 more
doaj +1 more source
Classically, HLA-DR expressed on antigen presenting cells (APC) initiates lymphocyte activation via presentation of peptides to TCR bearing CD4+ T-Cells.
Grit-Carsta Bulwin +12 more
doaj +1 more source
Background According to the definition of the International Society for Cell and Gene Therapy (ISCT), mesenchymal stromal cells (MSCs) do not express HLA-DR.
Zyrafete Kuçi +10 more
doaj +1 more source
Age-related changes of apoptotic cell death in human lymphocytes [PDF]
Apoptosis seems to be involved in immunosenescence associated with aging. Moreover, in lymphocytes (PBL) of patients with Alzheimer's disease, an increased susceptibility to the apoptotic pathway has been described possibly due to impaired protection of ...
Eckert, Anne +3 more
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Cancer vaccines: uses of HLA transgenic mice compared to genetically modified mice [PDF]
Many tumor antigens have been identified that can be targeted by the immune system. Animal models that have been genetically modified to express human HLA molecules instead of their own MHC antigens have shown to be valuable in the discovery of peptides ...
McArdle, SE
core
Origin of lymph node-derived lymphocytes in human hepatic allografts [PDF]
Hepatic allograft-derived lymph nodes were examined in the post-transplant period on order to determine the origin of lymphocytes and structural elements of the lymph node.
Chen, K +7 more
core +1 more source
"Induction of Thymic HLA-DR signaling with Alpha-smooth muscle Actin expression during the second and third trimesters of gestation " [PDF]
Less than 5% of prenatal thymoctes express HLA-DR before week 12 of gestation. However, the number of HLA-DR- positive cells increases during the late second and third trimesters of development. To determine the role of alpha-smooth muscle actin in fetal
Tamiolakis D +5 more
doaj
Generation of Human Epidermis-Derived Mesenchymal Stem Cell-like Pluripotent Cells and their reprogramming in mouse chimeras [PDF]
Stem cells can be derived from the embryo (embryonic stem cells, ESCs), from adult tissues (adult stem cells, ASCs), and by induction of fibroblasts (induced pluripotent stem cells, iPSs).
Bing Huang +21 more
core +1 more source
卵巢上皮癌中 HLA-DR 及 HLA-ABC 表达的临床意义
【目的】研究卵巢上皮癌(EOC)中HLA-DR及HLA-ABC的表达及其临床意义,为以HLA为靶点的肿瘤免疫治疗提供理论依据。【方法】应用免疫组织化学SP法检测57例卵巢上皮癌、35例卵巢良性上皮肿瘤及20例正常卵巢组织中HLA-DR及HLA-ABC的表达情况。【结果】①卵巢癌HLA-DR阳性率(33/57)显著高于良性肿瘤(4/35)及正常卵巢组织(1/20 ...
doaj
Immunomodulatory effects of human umbilical cord wharton's Jelly-Derived mesenchymal stem cells on differentiation, maturation and endocytosis of monocyte-derived dendritic cells [PDF]
The Wharton's jelly of the umbilical cord is believed to be a source of mesenchymal stem cells (MSCs) which can be therapeutically applied in degenerative diseases.
Bonab, M.M. +7 more
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