Медицинская иммунологияThe aim of our study was to evaluate the features of HLA-G and HLA-DR expression on lymphocytes of women and their children with congenital heart defects (CHD) under the influence of allogeneic and autologous blood sera.38 women and their children with ...
A. V. Shabaldin +3 more
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Haematologica, 2018 Formation of microthrombi is a hallmark of acquired thrombotic thrombocytopenic purpura. These microthrombi originate from insufficient processing of ultra large von Willebrand factor multimers by ADAMTS13 due to the development of anti-ADAMTS13 ...
Johana Hrdinová +12 more
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Alveolar macrophages in patients with pulmonary tuberculosis [PDF]
, 1988 Total and HLA-DR positive alveolar macrophages were enumerated in the broncho-alveolar lavage fluids of active pulmonary tuberculosis, inactive pulmonary tuberculosis (treated cases), nontuberculous lung disease patients and normal healthy individuals.
Narayanan, P R +4 more
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Multi-parameter immune profiling of peripheral blood mononuclear cells by multiplexed single-cell mass cytometry in patients with early multiple sclerosis [PDF]
, 2019 Multiple sclerosis (MS) is an inflammatory demyelinating and neurodegenerative disease of the central nervous system (CNS). Studies in rodent models demonstrated an association of CNS-infiltrating monocyte-derived macrophages with disease severity ...
Asseyer, Susanna +12 more
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Common Genetic Variant Association with Altered HLA Expression, Synergy with Pyrethroid Exposure, and Risk for Parkinson's Disease: An Observational and Case-Control Study. [PDF]
, 2015 Background/objectivesThe common non-coding single nucleotide polymorphism (SNP) rs3129882 in HLA-DRA is associated with risk for idiopathic Parkinson's disease (PD).
Boss, JM +11 more
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HLA-DR and the Development of Rheumatoid Arthritis
Autoimmunity, 1997 Susceptibility to develop Rheumatoid arthritis (RA) maps to a highly conserved amino acid motif ("the shared epitope") expressed in the third hypervariable region of different HLA-DRB1 alleles. This motif, namely QKRAA, QRRAA or RRRAA helps the development of RA by an unknown mechanism.
Auger, Isabelle, Roudier, Jean
openaire +2 more sources
Comparing Effects of BK Virus Agnoprotein and Herpes Simplex-1 ICP47 on MHC-I and MHC-II Expression
Clinical and Developmental Immunology, 2013 Background. Among human polyomaviruses, only BK virus (BKV) and JC virus (JCV) encode an agnoprotein upstream of VP1 on the viral late transcript. BKV agnoprotein is abundantly expressed late in the viral life cycle, but specific cellular and humoral ...
Michela Cioni +3 more
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Comparison of monocyte human leukocyte antigen-DR expression and stimulated tumor necrosis factor alpha production as outcome predictors in severe sepsis: A prospective observational study [PDF]
, 2016 BACKGROUND: Identifying patients in the immunosuppressive phase of sepsis is essential for development of immunomodulatory therapies. Little data exists comparing the ability of the two most well-studied markers of sepsis-induced immunosuppression, human
Ablordeppey, Enyo A +6 more
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Observational studies have shown a significant association between immune cells and heart failure (HF). Nevertheless, the precise biological mechanisms underlying this association remain unclear.
Yi Liu, Chenfu Shen, Yu Cao
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HLA-DR phenotypes and IgG, IgA and IgM antibody responses to Mycobacterium tuberculosis culture filtrate and 30 kDa antigens in pulmonary tuberculosis [PDF]
, 2004 The role of HLA-DR genetic make-up on the IgG, IgA and IgM antibody response to Mycobacterium tuberculosis culture filtrate and 30 kDa antigens was studied in pulmonary tuberculosis.
Kurian, S M +4 more
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