Results 51 to 60 of about 2,861,094 (164)

HLA-DR in Cytotoxic T Lymphocytes Predicts Breast Cancer Patients' Response to Neoadjuvant Chemotherapy

open access: yesFrontiers in Immunology, 2018
Prediction of breast cancer response to Neoadjuvant Chemotherapy (NACT) is an urgent need to promptly direct non-responder patients to alternative therapies.
Diana P. Saraiva   +7 more
doaj   +1 more source

HLA-DR+ CD8+ T-cells exhibit an effector memory profile.

open access: yes, 2019
A. Expression of CCR7, CD28, CD45RA, CD45RO, CD95, CD57, and CTLA-4 in HLA-DR/CD38-expressing CD8+ T-cells from a representative seronegative and HIV-infected individual. The numbers indicate the percentage of positive cells for each marker.
Paula A. Velilla (446105)   +3 more
core   +1 more source

Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan.

open access: yesPLoS Computational Biology, 2008
CD4 positive T helper cells control many aspects of specific immunity. These cells are specific for peptides derived from protein antigens and presented by molecules of the extremely polymorphic major histocompatibility complex (MHC) class II system. The
Morten Nielsen   +7 more
doaj   +1 more source

Potential role for HIV-specific CD38-/HLA-DR+ CD8+ T cells in viral suppression and cytotoxicity in HIV controllers. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND:HIV controllers (HIC) are rare HIV-1-infected patients who exhibit spontaneous viral control. HIC have high frequency of CD38-/HLA-DR+ HIV-specific CD8+ T cells. Here we examined the role of this subset in HIC status.
Stéphane Hua   +10 more
doaj   +1 more source

Allogeneic Hematopoietic Stem Cell Transplant recipients in Spain: Human Leucocyte Antigen characteristics and diversity by high-resolution analysis

open access: yes
There are many studies on the polymorphism of the HLA system in healthy donor populations, such as registries of unrelated bone marrow donors. Investigations on the characterization of the HLA complex in hematopoietic stem cell transplant (HSCT) patients,
Solano Vercet, Carlos   +3 more
core   +1 more source

CD8+ T cells from patients with cirrhosis display a phenotype that may contribute to cirrhosis-associated immune dysfunctionResearch in context

open access: yesEBioMedicine, 2019
: Background: Cirrhosis-associated immune dysfunction (CAID) contributes to high sepsis risk in patients with chronic liver disease. Various innate and; to a lesser extent; adaptive immune dysfunctions have been described as contributors to CAID leading
Fanny Lebossé   +16 more
doaj   +1 more source

The HLA-E Gene encodes two differentially regulated Transcripts and a Cell Surface Protein [PDF]

open access: yes, 1992
An HLA-E-specific oligonucleotide probe was used to study the expressioonf HLA-E. This probed etects two HLA-E transcripts, 1.8 and 2.7 kb in size, which are present in varying ratios in allt issues and cell lines investigated.
Honka, Thomas   +4 more
core   +1 more source

HLA-DR and -DQ gene polymorphism in Latvian patients with insulin-dependent diabetes mellitus

open access: yes, 1998
Latvian insulin-dependent diabetes mellitus (IDDM) patients (n=101) and healthy controls (n=111) were analyzed for HLA-DR and DQ polymorphism. DR3-DQ2 and DR4-DQ8 were positively associated and DR15-DQ6, DR13-DQ6, DR1-DQ5 and DQ7 negatively associated ...
Shtauvere, A   +3 more
core   +1 more source

HLA-B27 i HLA-DR w prognozowaniu przebiegu młodzieńczego idiopatycznego zapalenia stawów o początku uogólnionym

open access: yes, 2011
Przebieg młodzieńczego idiopatycznego zapalenia stawówo początku uogólnionym (UMIZS) jest zróżnicowany. W artykuleoceniono wpływ antygenu B27 i serii HLA klasy II – DR na postępchoroby, ciężkość objawów pozastawowych oraz rozwój amyloidozyu 47 chorych z ...
Elżbieta Musiej-Nowakowska   +3 more
core  

A Physical Map Including a New Class I Gene (cda12) of the Human Major Histocompatibility Complex (A2/313 Haplotype) Derived from a Monosomy 6 Mutant Cell Line [PDF]

open access: yes, 1989
To avoid interpretative problems due to restriction fragment length polymorphisms, the monosomy 6 mutant cell line BM19.7 was employed to establish a molecular map of the human major histocompatibility (HLA) complex in the A2,B13,Bw4,DRw6,DRw52,DQw1,DPw2
Pohla, Heike   +11 more
core   +1 more source

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