Results 201 to 210 of about 183,897 (254)

Accurate multi-population imputation of MICA, MICB, HLA-E, HLA-F and HLA-G alleles from genome SNP data. [PDF]

PLoS Comput Biol
Tammi S, Koskela S, Blood Service Biobank, Hyvärinen K, Partanen J, Ritari J.   +5 more
europepmc   +1 more source

Mtb-Specific HLA-E-Restricted T Cells Are Induced during Mtb Infection but Not after BCG Administration in Non-Human Primates and Humans. [PDF]

Vaccines (Basel)
Voogd L, van Wolfswinkel M, Satti I, White AD, Dijkman K, Gela A, van Meijgaarden KE, Franken KLMC, Marshall JL, Ottenhoff THM, Scriba TJ, McShane H, Sharpe SA, Verreck FAW, Joosten SA.   +14 more
europepmc   +1 more source

Obtaining Gene-Modified HLA-E-Expressing Feeder Cells for Stimulation of Natural Killer Cells. [PDF]

Pharmaceutics
Alekseeva NA, Streltsova MA, Vavilova JD, Ustiuzhanina MO, Palamarchuk AI, Boyko AA, Timofeev ND, Popodko AI, Kovalenko EI.   +8 more
europepmc   +1 more source

SARS-CoV-2 infection induces adaptive NK cell responses by spike protein-mediated induction of HLA-E expression. [PDF]

Emerg Microbes Infect
Hasan MZ, Claus M, Krüger N, Reusing S, Gall E, Bade-Döding C, Braun A, Watzl C, Uhrberg M, Walter L.   +9 more
europepmc   +1 more source

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HLA‐E and immunobiology of pregnancy

Tissue Antigens, 2006
AbstractRecently, it has been suggested that non‐classical antigens such as human leukocyte antigen (HLA)‐G and HLA‐E may interact with KIR receptors of NK cells which results into downregulation of immune response and helps in the maintenance of pregnancy.
P, Tripathi, S, Naik, S, Agrawal
openaire   +2 more sources

HLA-E and HLA-E-Bound Peptides: Recognition by Subsets of NK and T Cells

Current Pharmaceutical Design, 2009
In humans, major histocompatibility complex (MHC) class I molecules comprise the classical (class Ia) human leukocyte antigens (HLA)-A, -B, and -C, and the non-classical (class Ib) HLA-E, -F, -G and -H (HFE) molecules. The best-characterized MHC class Ib molecule is HLA-E. HLA-E was first described as a non-polymorphic ligand of the CD94/NKG2 receptors
PIETRA, GABRIELLA, Romagnani C, MORETTA, LORENZO, MINGARI, MARIA CRISTINA   +3 more
openaire   +2 more sources

The involvement of HLA-E and -F in pregnancy

Journal of Reproductive Immunology, 2006
The human MHC class I genes, HLA-E, -F and -G are referred to as non-classical or class Ib genes and are distinguished from their close relatives (the classical HLA class I genes) by expression patterns and low allelic polymorphism. To date, most studies that relate these molecules to the immunology of pregnancy have concerned only HLA-G.
Akiko, Ishitani, Noriko, Sageshima, Katsuhiko, Hatake   +2 more
openaire   +2 more sources

Molecular Typing of HLA-E

2012
Human leukocyte antigen-E (HLA-E) is a non-classical HLA class I gene that shows a limited degree of polymorphism compared to the classical HLA genes. The HLA-E molecule can bind peptides derived from the leader sequence of various HLA class I alleles and some viral homologues, including CMV.
Nina, Lauterbach, Christina E M, Voorter, Marcel G J, Tilanus   +2 more
openaire   +2 more sources

Peptide‐induced HLA‐E expression in human PBMCs is dependent on peptide sequence and the HLA‐E genotype

Tissue Antigens, 2015
AbstractHuman Leukocyte Antigen (HLA)‐E is a low‐polymorphic non‐classical HLA class I molecule which plays a crucial role in immune surveillance by presentation of peptides to T and natural killer (NK) cells. HLA‐E polymorphism is related to HLA‐E surface expression and is associated with patient outcome after stem cell transplantation.
Lauterbach, N., Wieten, L., Popeijus, H.E., Vanderlocht, J., van Zon, P.M., Voorter, C.E., Tilanus, M G.   +6 more
openaire   +3 more sources

Implications of HLA-E allele expression and different HLA-E ligand diversity for the regulation of NK cells

Human Immunology, 2000
The interaction of HLA-E with CD94/NKG2A is dependant on the binding of HLA class I signal sequence derived peptides to HLA-E. In the caucasoid population two HLA-E alleles are observed at equal frequencies. Here we study the functional differences between the two HLA-E molecules with regard to cell surface expression, peptide binding, and potential to
S, Maier, M, Grzeschik, E H, Weiss, M, Ulbrecht   +3 more
openaire   +2 more sources