Results 141 to 150 of about 121,761 (316)

Hyperacute Interleukin‐1β Production and Neutrophil Extracellular Trap Formation in the Cerebral Circulation of Stroke Patients with Large Vessel Occlusion

Annals of Neurology, EarlyView.
Acute ischemic stroke due to large vessel occlusion is associated with rapid intravascular immune activation. Analysis of arterial blood sampled distal to the thrombus during mechanical thrombectomy revealed increased extracellular adenosine triphosphate (ATP) and interleukin‐1β (IL‐1β) levels, evidence of inflammasome priming in monocytes, and ...
Justine Münsterberg, Caspar Brekenfeld, Hanna Englert, Marius Piepke, Regine J. Dress, Martin Oertel, Tina Fischer, Romy Hackbusch, Mingming Zha, Haodi Cai, Christian Casar, Ines S. Schädlich, Leo Winter, Alina Jander, Karoline Degenhardt, Maxim Bester, Fabian Flottmann, Uta Hanning, Brigitte Holst, Anna Worthman, Johanna Hiefner, Berenike Rutz, Eckhard Schlemm, Götz Thomalla, Bettina H. Clausen, Ann M. Stowe, Immo Prinz, Thiruma V. Arumugam, Markus Glatzel, Thomas Renné, Jens Fiehler, Eva Tolosa, Tim Magnus, Mathias Gelderblom   +33 more
wiley   +1 more source

Proinflammatory Epstein–Barr Virus Antibody Functions Track with Disease Activity in Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Epstein–Barr virus (EBV) has been implicated in the pathogenesis of multiple sclerosis (MS). Elevated immunoglobulin G (IgG) titers against EBV nuclear antigen 1 (EBNA1) represent the most consistent serological marker of MS risk, with levels remaining persistently elevated following disease onset.
Malina Behrens, Paula Terroba‐Navajas, Eline A.J. Willemse, Sabine Schädelin, Manuel Comabella, Christian Münz, Gordan Lauc, Yannic Bartsch, Jens Kuhle, Jan D. Lünemann   +9 more
wiley   +1 more source

Human Leukocyte Antigen HLA-G, HLA-C HLA-F and HLA-E placental profiles are altered in Severe Preeclampsia [PDF]

American Journal of Obstetrics and Gynecology, 2022
Caroline Dunk, Matthew Butcher, Jianhong Zhang, Heyam Heyder, Dan Geraghty, Stephen Lye, Leslie Myatt, Rinat Hackmon   +7 more
openaire   +1 more source

Single‐Cell Level Characterization of B Cell Depletion and Repopulation Following Rituximab in Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used to treat systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation.
Haerin Jang, Norzawani Buang, Catherine Sutherland, Wanseon Lee, Lauren Overend, Tarran S. Rupall, Katie L. Burnham, Matthew C. Pickering, Marina Botto, Emma E. Davenport   +9 more
wiley   +1 more source

Análise epidemiológica e de associação de polimorfismos do Complexo Principal de Histocompatibilidade com o câncer de mama em mulheres de Santa Catarina [PDF]

, 2012
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.O câncer de mama é uma doença multifatorial que resulta de interações complexas entre fatores genéticos, imunológicos, ambientais, comportamentais, hormonais
Hausmann, Leili Daiane
core  

Autoantibodies to Joint‐Related Peptides Are Associated With Onset of Rheumatoid Arthritis in Presymptomatic Seronegative Individuals

Arthritis &Rheumatology, EarlyView.
Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA) and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serologic markers. Methods We analyzed serum and plasma from three cohorts: presymptomatic individuals who later developed RA ...
Outi Sareila, Linda Johansson, Anders Lundquist, Monica Leu Agelii, Lei Cheng, Yibo He, Erik Lönnblom, Maria Andersson, Jan Kihlberg, Anders Esberg, Inger Gjertsson, Rikard Holmdahl, Solbritt Rantapää‐Dahlqvist   +12 more
wiley   +1 more source

Preliminary report of HLA (DNA) typing of Nigerians using sequence-specific primer technique

Nigerian Postgraduate Medical Journal, 2014
Aims and Objectives: This communication is an attempt to present the experience and a preliminary report of results over a one-year period. Patients and Methods: From December 2011 to December 2012, a prospective determination of the HLA types of 20 ...
R A Bolarinwa, A A Oyekunle, F A Arogundade, A A Sanusi, L Salawu, R A Togun, N O Akinola, M A Durosinmi, A A Akinsola   +8 more
doaj  

Association between Human Leukocyte Antigen E (HLA-E) Polymorphism, HLA-E Mismatch and Clinical Outcomes in Hematopoietic Cell Transplant for Acute Myeloid Leukemia and Myelodysplastic Syndrome

Transplantation and Cellular Therapy, 2023
Medhat Z Askar, Madhu Ragupathi, Mufaddal Mamawala, Anjali Bhatt, Jenifer Williams, Terry Knudsen, Scott Kang, Ender Karaca, David Samuel, Carolina Escobar, Nebu Koshy, Brian Berryman, Luis Pineiro, Jana Reynolds   +13 more
openaire   +1 more source

Molecular basis of human natural killer cell recognition of HLA-E (human leucocyte antigen-E) and its relevance to clearance of pathogen-infected and tumour cells

Clinical Science, 2000
HLA-E (human leucocyte antigen-E) is a conserved class I major histocompatibility molecule which has only limited polymorphism. It binds to the leader peptide derived from the polymorphic classical major histocompatibility molecules HLA-A, HLA-B and HLA-C.
openaire   +2 more sources

HLA and hemochromatosis disease association in São Miguel Island [PDF]

, 2008
Mestrado em Biologia Molecular e CelularA hemocromatose hereditária uma doença autossómica recessiva do metabolismo do ferro, geralmente associada à mutação C282Y no gene HFE. Presume-se que a origem desta mutação tenha ocorrido por acaso no haplótipo
Gomes, Cidália Maria Teixeira
core   +1 more source