Results 221 to 230 of about 171,039 (261)

Transcriptional regulation of HLA-G

Transplantation Proceedings, 1999
THE EXPRESSION of HLA class I molecules is essential in the immune response, as they present antigenderived peptides to cytotoxic T lymphocytes. The classical HLA class I genes (HLA-A, HLA-B, and HLA-C) are highly polymorphic and are ubiquitously expressed on most somatic cells.
S J, Gobin, V, Keijsers, C, Cheong, M, van Zutphen, P J, Van den Elsen   +4 more
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HLA‐G polymorphism and evolution

Tissue Antigens, 2007
AbstractSix proteins, one null allele and 22 human leukocyte antigen (HLA)‐G alleles were found in humans. Bonobo, chimpanzee and gorilla only show one allele and orangutan shows five alleles. All Cercopithecus alleles show stop codons at position 164 (Macaca mulatta with seven DNA alleles, Macaca fascicularis with seven DNA alleles and Cercopithecus ...
A, Arnaiz-Villena, J, Martinez-Laso, J I, Serrano-Vela, R, Reguera, J, Moscoso   +4 more
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Identification of a novel HLA‐G allele, HLA‐G*010113, in a Korean individual

Tissue Antigens, 2008
In the present study, a novel human leucocyte antigen‐G allele, G*010113, was identified via direct sequencing from donor gDNA in a Korean population. This allele differs from G*01010201 by a single nucleotide substitution, C to T, in codon 169 of exon 3 but did not result in any amino acid change.
H, Kang, H-S, Yun, J-K, Lee, K, Kwack
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A novel HLA‐G allele, HLA‐G*010111, in the Brazilian population

Tissue Antigens, 2007
The human leukocyte antigen‐G (HLA‐G) gene plays an important role in pregnancy and is related to negative signals for natural killer cells and T lymphocytes. Herein a new HLA‐G allele (HLA‐G*010111) is described in the Brazilian population – one of the most heterogeneous populations in the world.
E C, Castelli, C T, Mendes-Junior, C E V, Wiezel, N T A, Peres, A L, Simões, N M M, Rossi, E A, Donadi   +6 more
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A new allele, HLA-G*010120, is generated by a recombination event between HLA-G*01010101/02 and HLA-G*01010201

Tissue Antigens, 2010
Recombination between HLA-G*01010101/02 and HLA-G*01010201 generates HLA-G*010120.
I, Cervera, M A, Herraiz, J, Peñaloza, J, Vidart, J, Martinez-Laso   +4 more
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HLA‐G genotype and HLA‐G expression in systemic lupus erythematosus: HLA‐G as a putative susceptibility gene in systemic lupus erythematosus

Tissue Antigens, 2008
AbstractSystemic lupus erythematosus (SLE) is an autoimmune disease mainly mediated by the deposit of immune complexes and defects in T lymphocytes and antigen‐presenting cells along with a high production of T‐helper 2 cytokines. A tolerance‐inducible function of nonclassical class Ib human leukocyte antigen (HLA)‐G molecule in innate and adaptive ...
RIZZO, Roberta, Hviid T. V. F., GOVONI, Marcello, PADOVAN, Melissa, RUBINI, Michele, Melchiorri L., STIGNANI, Marina, CARTURAN, Sabrina, Grappa M. T., FOTINIDI, Maria, FERRETTI, Stefano, Voss A., Laustrup H., Junker P., TROTTA, Francesco, BARICORDI, Olavio   +15 more
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Impaired spontaneous endocytosis of HLA‐G

European Journal of Immunology, 1997
AbstractHLA‐G is a class Ib (non‐classical) major histocompatibility complex (MHC) protein expressed at the maternal‐fetal interface that inhibits natural killer (NK) cell‐mediated lysis in an allotype‐independent manner. Here we report that the spontaneous endocytosis of HLA‐G is severely reduced because of its short cytoplasmic tail.
Davis, Daniel M., Reyburn, Hugh T., Pazmany, Laszlo, Chiu, Isaac, Mandelboim, Ofer, Strominger, Jack L.   +5 more
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Soluble HLA-G in Rheumatoid Arthritis

Human Immunology, 2006
We investigated potential correlations between soluble HLA-G (sHLA-G) and soluble HLA class I (sHLA-I) levels, respectively, and parameters of disease activity or genetic factors determined by HLA-DRB1 and HLA-DQB1 in patients with rheumatoid arthritis (RA). SHLA-G plasma concentrations from 106 RA patients (mean age 59.8 years, 80 women) were assessed
Verbruggen, Leon, Rebmann, V., Demanet, Christian, De Cock, Seija, Grosse-Wilde, Hans   +4 more
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HLA-G in the Nervous System

Human Immunology, 2007
This review summarizes the current knowledge on the significance of human leukocyte antigen G (HLA-G) in the nervous system under physiologic and pathologic conditions. The central nervous system (CNS) has classically been viewed as an immune-privileged organ.
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Comparative reactivity of different HLA‐G monoclonal antibodies to soluble HLA‐G molecules

Tissue Antigens, 2000
Different HLA‐G monoclonal antibodies (mAbs) were first evaluated for their capability to identify soluble HLA‐G (sHLA‐G) in ELISA. Three of them, namely 87G, BFL.1 and MEM‐G/9, when used as coating mAbs together with W6/32 capture mAb, identified β2‐microglobulin (β2m)‐associated‐sHLA‐G but not soluble HLA‐B7 (sHLA‐B7) in cell culture supernatants ...
S, Fournel, X, Huc, M, Aguerre-Girr, C, Solier, M, Legros, C, Praud-Brethenou, M, Moussa, G, Chaouat, A, Berrebi, A, Bensussan, F, Lenfant, P, Le Bouteiller   +11 more
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