Results 11 to 20 of about 136,789 (304)

Antígenos de histocompatibilidad HLA-G y embarazo HLA-G histocompatibility antigens related to pregnancy

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2010
El componente HLA-G es una molécula clase I no clásica (Ib) del sistema principal de histocompatibilidad. Esta adopta 7 isoformas como resultado del empalme alternativo de un mismo RNA inmaduro; 4 se encuentran ligadas con la membrana (HLA-G1-G2-G3-G4) y
Luz M Morera Barrios, María E Alfonso Valdés, Catalino Ustáriz García, María de los A García García, Ana M Guerreiro Hernández, Rosa M Lam Díaz   +5 more
doaj   +1 more source

HLA-G-mediated inhibition of antigen-specific cytotoxic T lymphocytes [PDF]

International Immunology, 1999
In the present study, we demonstrate that the non-classical MHC class I molecule HLA-G impairs specific cytolytic T cell functions in addition to its well-established inhibition of NK lysis. The antigen-specific cytotoxic T lymphocyte (CTL) response analyzed was mediated by CD8(+) T cells specific for the influenza virus matrix epitope, M58-66 ...
F A, Le Gal, B, Riteau, C, Sedlik, I, Khalil-Daher, C, Menier, J, Dausset, J G, Guillet, E D, Carosella, N, Rouas-Freiss   +8 more
openaire   +2 more sources

Clinical correlates of human leucocyte antigen (HLA)-G in systemic sclerosis [PDF]

Clinical and Experimental Immunology, 2015
Summary Human leucocyte antigen (HLA)-G has a tolerogenic function and could play a role in the pathogenesis of immune-mediated diseases, including systemic sclerosis (SSc). The aim of this study was to evaluate HLA-G serum expression (sHLA-G) and the HLA-G gene 14 base pairs (bp) insertion/deletion (del−/del+) polymorphism in patients ...
Favoino E, Favia IE, VETTORI, Serena, Vicenti C, Prete M, VALENTINI, Gabriele, Perosa F.   +6 more
openaire   +4 more sources

Maturation of antigen-presenting cells is compromised in HLA-G transgenic mice [PDF]

International Immunology, 2001
The human MHC class Ib antigen HLA-G is thought to regulate maternal immune responses during pregnancy. Here we show that expression of HLA-G in transgenic mice diminished cellular immunity by inhibiting maturation of myelomonocytic cells into functional antigen-presenting cells (APC).
A, Horuzsko, F, Lenfant, D H, Munn, A L, Mellor   +3 more
openaire   +4 more sources

Expression and potential roles of HLA-G in human spermatogenesis and early embryonic development. [PDF]

PLoS ONE, 2014
As one of the non-classical major histocompatibility complex(MHC)-1 antigens, Human Leukocyte Antigen G (HLA-G), has been suggested as a prognostic marker to identify the embryo developmental potential. In the present study, we investigated the potential
Gui-Dong Yao, Yi-Min Shu, Sen-Lin Shi, Zhao-Feng Peng, Wen-Yan Song, Hai-Xia Jin, Ying-Pu Sun   +6 more
doaj   +1 more source

B Cells Control Mucosal-Associated Invariant T Cell Responses to Salmonella enterica Serovar Typhi Infection Through the CD85j HLA-G Receptor

Frontiers in Immunology, 2021
Mucosal-associated invariant T (MAIT) cells are an innate-like population of T cells that display a TCR Vα7.2+ CD161+ phenotype and are restricted by the nonclassical MHC-related molecule 1 (MR1).
Rosângela Salerno-Gonçalves, Tasmia Rezwan, David Luo, Hervé Tettelin, Marcelo B. Sztein, Marcelo B. Sztein   +5 more
doaj   +1 more source

Immunological Compatibility Status of Placenta-Derived Stem Cells is Mediated by Scaffold 3D Structure [PDF]

, 2018
Placenta-derived amniotic epithelial cells (AECs), a great cell source for tissue engineering and stem cell therapy, are immunologically inert in their native state; however, immunological changes in these cells after culture and differentiation have ...
Azizian, Sara, Bahrami, Soheyl, Katami, Fatemeh, Modaresifar, Khashayar, Mosaffa, Nariman, Niknejad, Hassan, Peirovi, Habibollah, Redl, Heinz, Tayebi, Lobat   +8 more
core   +2 more sources

Genetic and serological heterogeneity of the supertypic HLA-B locus specificities Bw4 and Bw6 [PDF]

, 1989
Gene cloning and sequencing of the HLA-B locus split antigens B38 (B16.1) and B39 (B16.2) allowed localization of their subtypic as well as their public specificities HLA-Bw4 or -Bw6 to the c~-helical region of the c~ 1 domain flanked by the amino acid ...
Engler-Blum, G., Gekeler, V., Müller, C. A., Schmidt, H., Steiert, I., Weiss, Elisabeth H.   +5 more
core   +1 more source

Human Histocompatibility Leukocyte Antigen (HLA)-G Molecules Inhibit NKAT3 Expressing Natural Killer Cells [PDF]

The Journal of Experimental Medicine, 1997
The crucial immunological function of the classical human major histocompatibility complex (MHC) class I molecules, human histocompatibility leukocyte antigen (HLA)-A, -B, and -C, is the presentation of peptides to T cells. A secondary function is the inhibition of natural killer (NK) cells, mediated by binding of class I molecules to NK receptors.
C, Münz, N, Holmes, A, King, Y W, Loke, M, Colonna, H, Schild, H G, Rammensee   +6 more
openaire   +3 more sources

HUMAN LEUKOCYTE ANTIGEN (HLA)-G: AS AN INVISIBILITY CLOAK FOR TUMOR CELLS IN HEMATOLOGICAL MALIGNANCIES

Hematology, Transfusion and Cell Therapy, 2023
Introduction: Hematological malignancies are a disease group that affects blood cells derived from myeloid or lymphoid lineage, resulting in impaired hematopoiesis. These neoplasms include mainly leukemias, lymphomas and multiple myeloma (MM).
TLP Ribeiro, GM Nogueira, M Souz-Barros, DS Pereira, VGRD Santos, JAC Neto, FS Alve-Hanna, AG Costa   +7 more
doaj   +1 more source