HLA-G Expression Is an Independent Predictor for Improved Survival in High Grade Ovarian Carcinomas
Aberrant expression of human leukocyte antigens (HLA) class I has prognostic importance in various cancers. Here, we evaluated the prognostic value of classical (A/B/C) and nonclassical (G/E) HLA expression in 169 high grade epithelial ovarian cancer ...
M. J. Rutten +6 more
doaj +1 more source
Determination of a predictive cleavage motif for eluted major histocompatibility complex class II ligands [PDF]
CD4+ T cells have a major role in regulating immune responses. They are activated by recognition of peptides mostly generated from exogenous antigens through the major histocompatibility complex (MHC) class II pathway.
Dhanda, Sandeep Kumar +7 more
core +6 more sources
Identification and validation of targets for cancer immunotherapy: from the bench-to-bedside [PDF]
Chapter 12 in Novel Gene Therapy ...
Brooks, Suzanne E. +4 more
core +3 more sources
Functional characterization of infiltrating T lymphocytes in human hepatic allografts [PDF]
We have employed recently developed techniques in T-cell culturing to study the nature and function of infiltrating hepatic allograft T cells. Using the rationale that intragraft T cells are activated during cell mediated damage to the allograft, we were
Adriana Zeevi +53 more
core +1 more source
The potential of HLA-G-bearing extracellular vesicles as a future element in HLA-G immune biology
The HLA-G molecule is a member of the non-classical HLA class I family. Its surface expression is physiologically restricted to the maternal-fetal interface and to immune privileged adult tissues.
Vera eRebmann
doaj +1 more source
Analogue peptides for the immunotherapy of human acute myeloid leukemia [PDF]
Accepted manuscript. The final publication is available at: http://link.springer.com/article/10.1007%2Fs00262-015-1762-9The use of peptide vaccines, enhanced by adjuvants, has shown some efficacy in clinical trials.
A Driessche Van +102 more
core +2 more sources
CD4+ Th immunogenicity of the Ascaris spp. secreted products [PDF]
Ascaris spp. is a major health problem of humans and animals alike, and understanding the immunogenicity of its antigens is required for developing urgently needed vaccines.
Bertazzon, Miriam +6 more
core +1 more source
The Many Faces of Human Leukocyte Antigen-G: Relevance to the Fate of Pregnancy
Pregnancy is an immunological paradox, where fetal antigens encoded by polymorphic genes inherited from the father do not provoke a maternal immune response.
Mette Dahl +2 more
doaj +1 more source
We have previously reported that serum levels of soluble HLA-A, -B, -C and -G antigens are elevated in HIV-infected subjects and decrease after antiretroviral theraphy.
G. Murdaca, P. Cagnati, F. Puppo
doaj +1 more source
Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma [PDF]
Immunotherapy approaches for pancreatic ductal adenocarcinoma (PDAC) have met with limited success. It has been postulated that a low mutation load may lead to a paucity of T cells within the tumor microenvironment (TME).
Alvarez, Hector A. +13 more
core +1 more source

