Results 31 to 40 of about 136,789 (304)

HLA-G Expression Is an Independent Predictor for Improved Survival in High Grade Ovarian Carcinomas

open access: yesJournal of Immunology Research, 2014
Aberrant expression of human leukocyte antigens (HLA) class I has prognostic importance in various cancers. Here, we evaluated the prognostic value of classical (A/B/C) and nonclassical (G/E) HLA expression in 169 high grade epithelial ovarian cancer ...
M. J. Rutten   +6 more
doaj   +1 more source

Determination of a predictive cleavage motif for eluted major histocompatibility complex class II ligands [PDF]

open access: yes, 2018
CD4+ T cells have a major role in regulating immune responses. They are activated by recognition of peptides mostly generated from exogenous antigens through the major histocompatibility complex (MHC) class II pathway.
Dhanda, Sandeep Kumar   +7 more
core   +6 more sources

Identification and validation of targets for cancer immunotherapy: from the bench-to-bedside [PDF]

open access: yes, 2013
Chapter 12 in Novel Gene Therapy ...
Brooks, Suzanne E.   +4 more
core   +3 more sources

Functional characterization of infiltrating T lymphocytes in human hepatic allografts [PDF]

open access: yes, 1986
We have employed recently developed techniques in T-cell culturing to study the nature and function of infiltrating hepatic allograft T cells. Using the rationale that intragraft T cells are activated during cell mediated damage to the allograft, we were
Adriana Zeevi   +53 more
core   +1 more source

The potential of HLA-G-bearing extracellular vesicles as a future element in HLA-G immune biology

open access: yesFrontiers in Immunology, 2016
The HLA-G molecule is a member of the non-classical HLA class I family. Its surface expression is physiologically restricted to the maternal-fetal interface and to immune privileged adult tissues.
Vera eRebmann
doaj   +1 more source

Analogue peptides for the immunotherapy of human acute myeloid leukemia [PDF]

open access: yes, 2015
Accepted manuscript. The final publication is available at: http://link.springer.com/article/10.1007%2Fs00262-015-1762-9The use of peptide vaccines, enhanced by adjuvants, has shown some efficacy in clinical trials.
A Driessche Van   +102 more
core   +2 more sources

CD4+ Th immunogenicity of the Ascaris spp. secreted products [PDF]

open access: yes, 2020
Ascaris spp. is a major health problem of humans and animals alike, and understanding the immunogenicity of its antigens is required for developing urgently needed vaccines.
Bertazzon, Miriam   +6 more
core   +1 more source

The Many Faces of Human Leukocyte Antigen-G: Relevance to the Fate of Pregnancy

open access: yesJournal of Immunology Research, 2014
Pregnancy is an immunological paradox, where fetal antigens encoded by polymorphic genes inherited from the father do not provoke a maternal immune response.
Mette Dahl   +2 more
doaj   +1 more source

Soluble HLA G serum levels in patients with the Acquired Immunodeficiency Syndrome affected by different AIDS-defining conditions before and after anti-retrovirel treatment

open access: yesJournal of Biological Research, 2011
We have previously reported that serum levels of soluble HLA-A, -B, -C and -G antigens are elevated in HIV-infected subjects and decrease after antiretroviral theraphy.
G. Murdaca, P. Cagnati, F. Puppo
doaj   +1 more source

Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma [PDF]

open access: yes, 2016
Immunotherapy approaches for pancreatic ductal adenocarcinoma (PDAC) have met with limited success. It has been postulated that a low mutation load may lead to a paucity of T cells within the tumor microenvironment (TME).
Alvarez, Hector A.   +13 more
core   +1 more source

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