Distribution of HLA epitope frequencies in Turkish population
Türk Biyokimya Dergisi, 2022 The antibodies interact with the “Human Leukocyte Antigen (HLA) antigens” at specific epitopes. “Epitopes” are present on a single HLA or shared by multiple antigens.
Oguz Fatma Savran +7 more
doaj +1 more source
Donor – recipient selection using epitope mismatches in kidney transplantation
Бюллетень сибирской медицины, 2021 Purpose. To evaluate the potential option of selecting donor–recipient pairs by using the number of epitopemismatches.Materials and methods. An observational cohort study was carried out, which included 824 adult recipients of ABO compatible deceased ...
A. V. Vatazin +2 more
doaj +1 more source
Expression analysis of HLA-E and NKG2A and NKG2C receptors points at a role for natural killer function in ankylosing spondylitis [PDF]
, 2018 Background. Ankylosing Spondylitis (AS) is a complex chronic inflammatory disease strongly associated with the majority of HLA-B27 alleles. HLA-E are non-classical MHC class I molecules that specifically interact with the natural killer receptors NKG2A ...
Angioni, Mm +12 more
core +1 more source
Disease recurrence and rejection following liver transplantation for autoimmune chronic active liver disease [PDF]
, 1992 Autoimmune chronic active liver disease (ACALD), a major indication for liver transplantation, is associated strongly with antigenic determinants HLA-B8 and DR3.
Block, GD +6 more
core +1 more source
HLA-DQA1 and HLA-DQB1 genotyping among lichen planus patients in Basrah province [PDF]
The Medical Journal of Basrah University, 2014 Background: Lichen planus is an inflammatory, pruritic disease of the skin and mucus membranes, which can be either generalized or localized. Many studies indicated that human leukocyte antigens might have a role in lichen planus (LP).
Nibras S. Al-Ammar
doaj +1 more source
Allelic variation in HLA-B and HLA-C sequences and the evolution of the HLA-B alleles [PDF]
, 1989 Several new HLA-B (B8, B51, Bw62)- and HLA-C (Cw6, Cw7)-specific genes were isolated either as genomic cosmid or cDNA clones to study the diversity of HLA antigens.
Doerner, C. +4 more
core +1 more source
Efficient HLA imputation from sequential SNPs data by Transformer [PDF]
arXiv, 2022 Human leukocyte antigen (HLA) genes are associated with a variety of diseases, however direct typing of HLA is time and cost consuming. Thus various imputation methods using sequential SNPs data have been proposed based on statistical or deep learning models, e.g. CNN-based model, named DEEP*HLA.
arxiv
AIF-1 gene does not confer susceptibility to Behçet's disease: Analysis of extended haplotypes in Sardinian population [PDF]
, 2018 Background BehcEet's disease (BD) is a polygenic immune-mediated disorder characterized by a close association with the HLA-B∗51 allele. The HLA region has a strong linkage disequilibrium (LD) and carries several genetic variants (e.g. MIC-A, TNF-α genes)
Angioni, Mm +11 more
core +2 more sources
Indian Journal of Pathology and Microbiology, 2023 Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder and has complex etiopathogenesis. The most appropriate hypothesis states that genetic susceptibility in the presence of environmental risk factors predisposes to SLE.
Ranjan S. Rana +5 more
doaj +1 more source
Simple models of the chemical field around swimming plankton [PDF]
, 2010 Background. Cervical cancer is the fourth most common cancer in women, and we recently reported human leukocyte antigen (HLA) alleles showing strong associations with cervical neoplasia risk and protection.
Bao, X +33 more
core +2 more sources