Results 31 to 40 of about 589,195 (286)

Factors influencing transfusion-associated HLA sensitization in patients bridged to heart transplantation using ventricular assist device. [PDF]

open access: yes, 2020
BackgroundBridging heart failure patients with mechanical ventricular assist devices (VAD) enables access to transplantation. However, VAD is associated with increased risk for anti-HLA antibodies associated with rejection of subsequent allografts ...
Adler, Eric   +5 more
core   +1 more source

Comprehensive Analysis of HLA-A, HLA-B, HLA-C, HLA-DRB1, and HLA-DQB1 Loci and Squamous Cell Cervical Cancer Risk [PDF]

open access: yesCancer Research, 2008
Abstract Variation in human major histocompatibility genes may influence the risk of squamous cell cervical cancer (SCC) by altering the efficiency of the T-cell–mediated immune response to human papillomavirus (HPV) antigens. We used high-resolution methods to genotype human leukocyte antigen (HLA) class I (A, B, and Cw) and class II ...
Madeleine, Margaret M.   +9 more
openaire   +2 more sources

HLA-DR in Cytotoxic T lymphocytes predicts breast cancer patients' response to neoadjuvant chemotherapy [PDF]

open access: yes, 2018
Prediction of breast cancer response to Neoadjuvant Chemotherapy (NACT) is an urgent need to promptly direct non-responder patients to alternative therapies.
Borralho, Paula   +4 more
core   +2 more sources

HLA and cross-reactive antigen group matching for cadaver kidney allocation [PDF]

open access: yes, 1997
Background. Allocation of cadaver kidneys by graded human leukocyte antigen (HLA) compatibility scoring arguably has had little effect on overall survival while prejudicing the transplant candidacy of African-American and other hard to match populations.
Allan Donner   +54 more
core   +1 more source

Tetrameric complexes of HLA-E, HLA-F, and HLA-G

open access: yesJournal of Immunological Methods, 2002
HLA-E, HLA-F, and HLA-G are human nonclassical MHC class Ib molecules. To study the function and identify potential ligands of these molecules, we constructed tetrameric complexes. In this brief review, we discuss the methods used to produce such tetramers and the interesting results they provided. HLA-E tetramers bound to natural killer (NK) cells and
Allan, D   +4 more
openaire   +3 more sources

Recurrent Guillain-Barré and Fisher Syndromes in Two Patients Who Were Subsequently Diagnosed with Aplastic Anemia

open access: yesCase Reports in Neurology, 2020
Guillain-Barré (GBS) and Fisher (FS) syndromes rarely recur and the characteristics of recurrence have not been fully elucidated. We describe the cases of 2 patients with GBS or FS that recurred more than twice and who were subsequently diagnosed with ...
Saori Tomohara   +11 more
doaj   +1 more source

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire [PDF]

open access: yes, 2012
Idiosyncratic adverse drug reactions are unpredictable, dose independent and potentially life threatening; this makes them a major factor contributing to the cost and uncertainty of drug development. Clinical data suggest that many such reactions involve
A. Lucas   +47 more
core   +4 more sources

SEROLOGICAL MARKERS OF CELIAC DISEASE AND HLA II ANTIGENS IN CHILDREN AND ADOLESCENTS WITH DIABETES MELLITUS TYPE 1

open access: yesВопросы современной педиатрии, 2012
We have studied incidenceof immunological markers of celiac disease in children with diabetes mellitus type 1 (DM1) and their correlation with clinical peculiarities and polymorphous alleles of HLA. It was shown that incidence of celiac markers is higher
E. O. Hennesy   +6 more
doaj   +1 more source

The economic implications of HLA matching in cadaveric renal transplantation. [PDF]

open access: yes, 1999
Background: The potential economic effects of the allocation of cadaveric kidneys on the basis of tissue-matching criteria are controversial. We analyzed the economic costs associated with the transplantation of cadaveric kidneys with various numbers of ...
Brennan, Daniel C   +9 more
core   +2 more sources

A common HLA-DPA1 variant is associated with hepatitis B virus infection but fails to distinguish active from inactive Caucasian carriers [PDF]

open access: yes, 2012
Background and Aims: Chronic infection with the hepatitis B virus (HBV) is a major health issue worldwide. Recently, single nucleotide polymorphisms (SNPs) within the human leukocyte antigen (HLA)-DP locus were identified to be associated with HBV ...
Vermehren, Johannes   +7 more
core   +1 more source

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