Results 1 to 10 of about 195,520 (337)

Prediction of immunogenicity of Rh antigens using in silico analysis of binding to human leukocyte antigen peptide, Basic/Translational Research. [PDF]

open access: yesPLoS ONE
The association between human leukocyte antigen (HLA) types and blood group alloimmunization remains unclear. Previous studies have predominantly focused on predicting immunization events in cancer immunotherapy, but not blood group antigens.
Hee-Jeong Youk   +4 more
doaj   +2 more sources

HLA and pathogens in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and other post-infection conditions [PDF]

open access: yesScientific Reports
Viral infections have been widely implicated in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) pathogenesis. Recent evidence has also identified certain Human Leukocyte Antigen (HLA) alleles that are significantly associated with ME/CFS risk/
Apostolos P. Georgopoulos   +2 more
doaj   +2 more sources

Current research status of HLA in immune‐related diseases

open access: yesImmunity, Inflammation and Disease, 2021
Human leukocyte antigen (HLA), also known as human major histocompatibility complex (MHC), is encoded by the HLA gene complex, and is currently known to have the highest gene density and the most polymorphisms among human chromosomal areas.
Bingnan Liu, Yuanyuan Shao, Rong Fu
doaj   +1 more source

Eplet-Predicted Antigens: An Attempt to Introduce Eplets into Unacceptable Antigen Determination and Calculated Panel-Reactive Antibody Calculation Facilitating Kidney Allocation

open access: yesDiagnostics, 2022
(1) Calculated panel-reactive antibody (CPRA) is a measure of sensitization based on unacceptable antigens (UAs). Determination of UAs based on single-antigen bead assays at allele or antigen levels may be inappropriate.
Wenrui Wu   +11 more
doaj   +1 more source

Human leukocyte antigen variation among Iranian renal transplant recipients [PDF]

open access: yesJournal of Nephropathology, 2012
Background: HLA typing analysis is important in renal transplant patients. Objectives: We made a plan to determine the most frequent HLA antigens in Iranian kidney transplant patients.
Behzad Einollahi   +2 more
doaj   +1 more source

The Mycobacterium tuberculosis phagosome is a HLA-I processing competent organelle. [PDF]

open access: yesPLoS Pathogens, 2009
Mycobacterium tuberculosis (Mtb) resides in a long-lived phagosomal compartment that resists maturation. The manner by which Mtb antigens are processed and presented on MHC Class I molecules is poorly understood. Using human dendritic cells and IFN-gamma
Jeff E Grotzke   +6 more
doaj   +1 more source

Analysis of HLA-Ⅰ antibody specificity and estimation of antigen immunogenicity: 96 patients recieved genotype-matched platelet transfusions

open access: yesZhongguo shuxue zazhi, 2022
Objective To analyze the specificity of HLA class-Ⅰ antibody in the patients received HLA-matched platelet transfusions and estimate the relative immunogenicity of HLA-Ⅰ antigens.
Ying LIU   +6 more
doaj   +1 more source

Behaviour of non-donor specific antibodies during rapid re-synthesis of donor specific HLA antibodies after antibody incompatible renal transplantation [PDF]

open access: yes, 2013
Background: HLA directed antibodies play an important role in acute and chronic allograft rejection. During viral infection of a patient with HLA antibodies, the HLA antibody levels may rise even though there is no new immunization with antigen ...
Briggs, David, Dr.   +11 more
core   +18 more sources

The Humoral Theory of Transplantation: Epitope Analysis and the Pathogenicity of HLA Antibodies. [PDF]

open access: yes, 2016
Central to the humoral theory of transplantation is production of antibodies by the recipient against mismatched HLA antigens in the donor organ. Not all mismatches result in antibody production, however, and not all antibodies are pathogenic.
Farber, John, Filippone, Edward J
core   +8 more sources

Peculiarities of distribution of HLA class I antigens in patients with lihen planus

open access: yesVestnik Dermatologii i Venerologii, 2021
The article presents data on the distribution characteristics of the HLA class I system antigens in patients with lichen planus. Aim. To study the patterns of distribution of HLA class I antigens in the general group.
Irina I. Zakhur   +3 more
doaj   +1 more source

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