Results 1 to 10 of about 180,078 (140)
The Humoral Theory of Transplantation: Epitope Analysis and the Pathogenicity of HLA Antibodies [PDF]
Journal of Immunology Research, 2016 Central to the humoral theory of transplantation is production of antibodies by the recipient against mismatched HLA antigens in the donor organ. Not all mismatches result in antibody production, however, and not all antibodies are pathogenic.
Edward J. Filippone, John L. Farber
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A novel HLA-B18 restricted CD8+ T cell epitope is efficiently cross-presented by dendritic cells from soluble tumor antigen [PDF]
, 2012 NY-ESO-1 has been a major target of many immunotherapy trials because it is expressed by various cancers and is highly immunogenic. In this study, we have identified a novel HLA-B*1801-restricted CD8<sup>+</sup>T cell epitope, NY-ESO-1<sub&
Ashley J. Knights +18 more
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Current research status of HLA in immune‐related diseases
Immunity, Inflammation and Disease, 2021 Human leukocyte antigen (HLA), also known as human major histocompatibility complex (MHC), is encoded by the HLA gene complex, and is currently known to have the highest gene density and the most polymorphisms among human chromosomal areas.
Bingnan Liu, Yuanyuan Shao, Rong Fu
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Diagnostics, 2022 (1) Calculated panel-reactive antibody (CPRA) is a measure of sensitization based on unacceptable antigens (UAs). Determination of UAs based on single-antigen bead assays at allele or antigen levels may be inappropriate.
Wenrui Wu +11 more
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Human leukocyte antigen variation among Iranian renal transplant recipients [PDF]
Journal of Nephropathology, 2012 Background: HLA typing analysis is important in renal transplant patients. Objectives: We made a plan to determine the most frequent HLA antigens in Iranian kidney transplant patients.
Behzad Einollahi +2 more
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Zhongguo shuxue zazhi, 2022 Objective To analyze the specificity of HLA class-Ⅰ antibody in the patients received HLA-matched platelet transfusions and estimate the relative immunogenicity of HLA-Ⅰ antigens.
Ying LIU +6 more
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The Mycobacterium tuberculosis phagosome is a HLA-I processing competent organelle. [PDF]
PLoS Pathogens, 2009 Mycobacterium tuberculosis (Mtb) resides in a long-lived phagosomal compartment that resists maturation. The manner by which Mtb antigens are processed and presented on MHC Class I molecules is poorly understood. Using human dendritic cells and IFN-gamma
Jeff E Grotzke +6 more
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Peculiarities of distribution of HLA class I antigens in patients with lihen planus
Vestnik Dermatologii i Venerologii, 2021 The article presents data on the distribution characteristics of the HLA class I system antigens in patients with lichen planus. Aim. To study the patterns of distribution of HLA class I antigens in the general group.
Irina I. Zakhur +3 more
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Identification of presented SARS-CoV-2 HLA class I and HLA class II peptides using HLA peptidomics
Cell Reports, 2021 Summary: The human leukocyte antigen (HLA)-bound viral antigens serve as an immunological signature that can be selectively recognized by T cells. As viruses evolve by acquiring mutations, it is essential to identify a range of presented viral antigens ...
Adi Nagler +18 more
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HLA antigens in syphilis patients in Tuvinian population
Бюллетень сибирской медицины, 2008 have examined 133 healthy donors, 41 syphilis patients with symptoms, and 45 patients with early latent syphilis. All the examined persons were grouped by class I HLA antigens using the standard microlymphocytotoxic test.
A. P. Obukhov +3 more
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