Results 1 to 10 of about 1,392,329 (286)

Prediction of immunogenicity of Rh antigens using in silico analysis of binding to human leukocyte antigen peptide, Basic/Translational Research. [PDF]

PLoS ONE
The association between human leukocyte antigen (HLA) types and blood group alloimmunization remains unclear. Previous studies have predominantly focused on predicting immunization events in cancer immunotherapy, but not blood group antigens.
Hee-Jeong Youk, Yong-Joon Cho, Yong-Hyun Han, Seong Who Kim, Dae-Hyun Ko   +4 more
doaj   +2 more sources

HLA and pathogens in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and other post-infection conditions [PDF]

Scientific Reports
Viral infections have been widely implicated in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) pathogenesis. Recent evidence has also identified certain Human Leukocyte Antigen (HLA) alleles that are significantly associated with ME/CFS risk/
Apostolos P. Georgopoulos, Lisa M. James, Philip K. Peterson   +2 more
doaj   +2 more sources

Current research status of HLA in immune‐related diseases

Immunity, Inflammation and Disease, 2021
Human leukocyte antigen (HLA), also known as human major histocompatibility complex (MHC), is encoded by the HLA gene complex, and is currently known to have the highest gene density and the most polymorphisms among human chromosomal areas.
Bingnan Liu, Yuanyuan Shao, Rong Fu
doaj   +1 more source

Eplet-Predicted Antigens: An Attempt to Introduce Eplets into Unacceptable Antigen Determination and Calculated Panel-Reactive Antibody Calculation Facilitating Kidney Allocation

Diagnostics, 2022
(1) Calculated panel-reactive antibody (CPRA) is a measure of sensitization based on unacceptable antigens (UAs). Determination of UAs based on single-antigen bead assays at allele or antigen levels may be inappropriate.
Wenrui Wu, Huanxi Zhang, Jinghong Tan, Qian Fu, Jun Li, Chenglin Wu, Huiting Huang, Bowen Xu, Liuting Ling, Longshan Liu, Xiaojun Su, Changxi Wang   +11 more
doaj   +1 more source

Human leukocyte antigen variation among Iranian renal transplant recipients [PDF]

Journal of Nephropathology, 2012
Background: HLA typing analysis is important in renal transplant patients. Objectives: We made a plan to determine the most frequent HLA antigens in Iranian kidney transplant patients.
Behzad Einollahi, Zohreh Rostami, Mojtaba Teimoori   +2 more
doaj   +1 more source

The Mycobacterium tuberculosis phagosome is a HLA-I processing competent organelle. [PDF]

PLoS Pathogens, 2009
Mycobacterium tuberculosis (Mtb) resides in a long-lived phagosomal compartment that resists maturation. The manner by which Mtb antigens are processed and presented on MHC Class I molecules is poorly understood. Using human dendritic cells and IFN-gamma
Jeff E Grotzke, Melanie J Harriff, Anne C Siler, Dawn Nolt, Jacob Delepine, Deborah A Lewinsohn, David M Lewinsohn   +6 more
doaj   +1 more source

Analysis of HLA-Ⅰ antibody specificity and estimation of antigen immunogenicity: 96 patients recieved genotype-matched platelet transfusions

Zhongguo shuxue zazhi, 2022
Objective To analyze the specificity of HLA class-Ⅰ antibody in the patients received HLA-matched platelet transfusions and estimate the relative immunogenicity of HLA-Ⅰ antigens.
Ying LIU, Xinyu HUANG, Bing ZHANG, Gang XU, Xianguo XU, Ji HE, Faming ZHU   +6 more
doaj   +1 more source

Peculiarities of distribution of HLA class I antigens in patients with lihen planus

Vestnik Dermatologii i Venerologii, 2021
The article presents data on the distribution characteristics of the HLA class I system antigens in patients with lichen planus. Aim. To study the patterns of distribution of HLA class I antigens in the general group.
Irina I. Zakhur, Sergei V. Koshkin, Galina A. Zaitseva, Varvara A. Bobro   +3 more
doaj   +1 more source

HLA antigens in syphilis patients in Tuvinian population

Бюллетень сибирской медицины, 2008
have examined 133 healthy donors, 41 syphilis patients with symptoms, and 45 patients with early latent syphilis. All the examined persons were grouped by class I HLA antigens using the standard microlymphocytotoxic test.
A. P. Obukhov, V. I. Prokhorenkov, L. Ye. Pospelov, Yu. V. Karacheva   +3 more
doaj   +1 more source

Differences in Immunogenicity of HLA Antigens and the Impact of Cross-Reactivity on the Humoral Response

Transplantation, 2014
Background Information about differences in immunogenicity of various HLA antigens may help guide donor selection and identify mismatches to avoid for patients likely to need retransplantation.
D. Lucas, M. Leffell, A. Zachary
semanticscholar   +1 more source