Results 1 to 10 of about 96,168 (98)

Identification and biophysical characterization of Plasmodium peptide binding by common African HLAs [PDF]

open access: yesScientific Reports
Human Leukocyte Antigens (HLA) are immunoreceptors that present peptide antigens at the cell surface to T cells as a primary mechanism of immune surveillance.
Marielle B. Frooman   +6 more
doaj   +2 more sources

Current research status of HLA in immune‐related diseases

open access: yesImmunity, Inflammation and Disease, 2021
Human leukocyte antigen (HLA), also known as human major histocompatibility complex (MHC), is encoded by the HLA gene complex, and is currently known to have the highest gene density and the most polymorphisms among human chromosomal areas.
Bingnan Liu, Yuanyuan Shao, Rong Fu
doaj   +1 more source

Eplet-Predicted Antigens: An Attempt to Introduce Eplets into Unacceptable Antigen Determination and Calculated Panel-Reactive Antibody Calculation Facilitating Kidney Allocation

open access: yesDiagnostics, 2022
(1) Calculated panel-reactive antibody (CPRA) is a measure of sensitization based on unacceptable antigens (UAs). Determination of UAs based on single-antigen bead assays at allele or antigen levels may be inappropriate.
Wenrui Wu   +11 more
doaj   +1 more source

Analysis of HLA-Ⅰ antibody specificity and estimation of antigen immunogenicity: 96 patients recieved genotype-matched platelet transfusions

open access: yesZhongguo shuxue zazhi, 2022
Objective To analyze the specificity of HLA class-Ⅰ antibody in the patients received HLA-matched platelet transfusions and estimate the relative immunogenicity of HLA-Ⅰ antigens.
Ying LIU   +6 more
doaj   +1 more source

Human leukocyte antigen variation among Iranian renal transplant recipients [PDF]

open access: yesJournal of Nephropathology, 2012
Background: HLA typing analysis is important in renal transplant patients. Objectives: We made a plan to determine the most frequent HLA antigens in Iranian kidney transplant patients.
Behzad Einollahi   +2 more
doaj   +1 more source

The Mycobacterium tuberculosis phagosome is a HLA-I processing competent organelle. [PDF]

open access: yesPLoS Pathogens, 2009
Mycobacterium tuberculosis (Mtb) resides in a long-lived phagosomal compartment that resists maturation. The manner by which Mtb antigens are processed and presented on MHC Class I molecules is poorly understood. Using human dendritic cells and IFN-gamma
Jeff E Grotzke   +6 more
doaj   +1 more source

Peculiarities of distribution of HLA class I antigens in patients with lihen planus

open access: yesVestnik Dermatologii i Venerologii, 2021
The article presents data on the distribution characteristics of the HLA class I system antigens in patients with lichen planus. Aim. To study the patterns of distribution of HLA class I antigens in the general group.
Irina I. Zakhur   +3 more
doaj   +1 more source

HLA antigens in syphilis patients in Tuvinian population

open access: yesБюллетень сибирской медицины, 2008
have examined 133 healthy donors, 41 syphilis patients with symptoms, and 45 patients with early latent syphilis. All the examined persons were grouped by class I HLA antigens using the standard microlymphocytotoxic test.
A. P. Obukhov   +3 more
doaj   +1 more source

Optimized Whole Genome Association Scanning for Discovery of HLA Class I-Restricted Minor Histocompatibility Antigens

open access: yesFrontiers in Immunology, 2020
Patients undergoing allogeneic stem cell transplantation as treatment for hematological diseases face the risk of Graft-versus-Host Disease as well as relapse. Graft-versus-Host Disease and the favorable Graft-versus-Leukemia effect are mediated by donor
Kyra J. Fuchs   +14 more
doaj   +1 more source

Peculiarities of phenotypes of patients with pyelo- and glomerulonephritis by HLA distribution analysis

open access: yesУкраїнський Журнал Нефрології та Діалізу, 2018
Studies devoted to the role of human leucocyte antigens (HLA) in pathogenesis of chronic kidney disease (CKD) have demonstrated the associative links of the HLA antigens, which stipulate the relative and attributive risks of some autoimmune diseases ...
V. Driianska   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy