Results 171 to 180 of about 111,549 (295)

Harnessing chimeric antigen receptor macrophages against solid tumors

open access: yesCancer Communications, EarlyView.
Abstract Macrophages are prevalent in multiple tumors and exhibit diverse and potent functional activities. Therapeutic reprogramming of macrophage phenotypes represents a promising strategy for cancer immunotherapy. Engineering chimeric antigen receptors (CARs) to endow macrophages with anti‐tumor capacities demonstrated encouraging efficacy ...
Mengru Wang   +3 more
wiley   +1 more source

MHCquant2 refines immunopeptidomics tumor antigen discovery. [PDF]

open access: yesGenome Biol
Scheid J   +13 more
europepmc   +1 more source

Insights Into Patient‐Level Exposure to Actionable Pharmacogenomic Medications in Australia Using a New National Pharmacogenomic Guideline

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
This study assessed the use of 35 pharmacogenomic (PGx) medications listed in the Royal College of Pathologists of Australasia (RCPA) guideline, estimated the potential costs of subsidizing PGx testing in Australia, and predicted related prescribing changes.
Bella D. Ianni   +3 more
wiley   +1 more source

Analyses of HLA antigens, especially HLA-A and -B interlocus antigen, on platelets with monoclonal antibodies and elisa assay.

open access: bronze, 1987
Yoshisuke Nose   +7 more
openalex   +2 more sources

UGT1A1 and Sacituzumab Govitecan Toxicity: A Systematic Review and Meta‐Analysis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Sacituzumab govitecan (SG), a humanized antibody‐drug conjugate, enables intra‐tumor delivery of SN‐38, the active metabolite of irinotecan, with the aim of increasing efficacy. SN‐38 is predominantly inactivated by the polymorphically expressed uridine diphosphate glucuronosyltransferase 1A1 (UGT1AA) where reduced activity can lead to toxicity.
Cinzia Dello Russo   +4 more
wiley   +1 more source

Preclinical development of an mRNA-based multiepitope immunotherapeutic for glioblastoma. [PDF]

open access: yesCancer Immunol Immunother
Lutz J   +8 more
europepmc   +1 more source

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