Results 211 to 220 of about 111,549 (295)
ABSTRACT Sickle cell anemia (SCA) is a genetic disorder that presents with a variety of systemic complications, including gastrointestinal (GI) manifestations. These GI symptoms can overlap with those of digestive autoimmune diseases (DAD) such as inflammatory bowel disease (IBD) and autoimmune hepatitis (AIH), complicating the diagnosis and management.
Saray Mesonero Cavia+3 more
wiley +1 more source
THLANet: A deep learning framework for predicting TCR-pHLA binding in immunotherapy applications. [PDF]
Long X+10 more
europepmc +1 more source
ABSTRACT Transporter associated with antigen presentation (TAP) deficiency syndrome (TDS) is a rare primary immunodeficiency (PID) characterised by a broad spectrum of clinical manifestations, with noninfectious cutaneous granulomas (CG) being a common feature.
A. Fernández‐Galván+8 more
wiley +1 more source
ABSTRACT Periodontal ligament stem cells (PDLSCs) are derived from periodontal tissue and can differentiate into osteoblasts, which are ideal materials for alveolar bone repair and periodontal tissue regeneration. In this study, we aimed to explore the effects of Y‐box binding protein 1 (YB‐1) on the osteogenic differentiation and proliferation of ...
Yun‐Hao Xi+5 more
wiley +1 more source
Next-generation cancer vaccines: targeting cryptic and non-canonical antigens for precision immunotherapy. [PDF]
Anilkumar AS+2 more
europepmc +1 more source
MetE: a promising protective antigen for tuberculosis vaccine development. [PDF]
Almujri SS+11 more
europepmc +1 more source
CAR-T cell engineered with TCR-like antibody specific for HBV surface antigen epitope E183-91/HLA-A *0201 exhibit potent activity against HBV-HCC. [PDF]
Wang F+15 more
europepmc +1 more source
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin+8 more
wiley +1 more source
Two homologous sequences of Grp78 and HSP70 represent tumor antigens shared with streptococcal superantigens in eliciting an antitumor immune response: an immunoinformatic investigation. [PDF]
Finotti P.
europepmc +1 more source