Results 271 to 280 of about 177,468 (356)

Aberrant immunophenotypic expressions in childhood acute leukemias: A tertiary care hospital experience. [PDF]

Pak J Med Sci
Saqlain N, Hareem S, Batool F, Mahmood K.   +3 more
europepmc   +1 more source

EXPRESSION OF HLA ANTIGENS ON RENAL TUBULAR CELLS IN CULTURE

, 1986
G. Alex Bishop, Bruce M. Hall, Michael Suranyi, David J. Tiller, John S. Horvath, Geoffrey G. Duggin   +5 more
openalex   +1 more source

Histologic and molecular features shared between antibody‐mediated rejection of kidney allografts and chronic histiocytic intervillositis support common pathogenesis

The Journal of Pathology, EarlyView.
Abstract Chronic histiocytic intervillositis (CHI) is an inflammatory condition of the placenta, characterised by an abnormal, mainly macrophagic infiltrate within the intervillous space. Recent research suggests that CHI results from a ‘maternal‐foetal rejection’ mechanism, because at least some CHI cases fulfil the criteria for antibody‐mediated ...
Léonie Albersammer, Juliette Leon, Jelena Martinovic, Jessy Dagobert, Emilie Lebraud, Bettina Bessières, Laurence Loeuillet, Maëva Eloudzeri, Alexandre J. Vivanti, Grégoire Dumery, Valérie Marchaudon, Cristina Antal, Anne‐Sophie Korganow, Thibaud Quibel, Nathalie Costedoat‐Chalumeau, Vassilis Tsatsaris, Alexandra Benachi, Julien Zuber, Marion Rabant   +18 more
wiley   +1 more source

A naturally selected αβ T cell receptor binds HLA-DQ2 molecules without co-contacting the presented peptide. [PDF]

Nat Commun
Lim JJ, Jones CM, Loh TJ, Dao HT, Tran MT, Tye-Din JA, La Gruta NL, Rossjohn J.   +7 more
europepmc   +1 more source

A Tc1‐ and Th1‐T‐lymphocyte‐rich tumor microenvironment is a hallmark of MSI colorectal cancer

The Journal of Pathology, EarlyView.
Abstract Microsatellite instability is a strong predictor of response to immune checkpoint therapy and patient outcome in colorectal cancer. Although enrichment of distinct T‐cell subpopulations has been determined to impact the response to immune checkpoint therapy and patient outcome, little is known about the underlying changes in the composition of
Zhihao Huang, Tim Mandelkow, Nicolaus F Debatin, Magalie C J Lurati, Julia Ebner, Jonas B Raedler, Elena Bady, Jan H Müller, Ronald Simon, Eik Vettorazzi, Anne Menz, Katharina Möller, Natalia Gorbokon, Guido Sauter, Maximilian Lennartz, Andreas M Luebke, Doris Höflmayer, Till Krech, Patrick Lebok, Christoph Fraune, Andrea Hinsch, Frank Jacobsen, Andreas H Marx, Stefan Steurer, Sarah Minner, David Dum, Sören Weidemann, Christian Bernreuther, Till S Clauditz, Eike Burandt, Niclas C Blessin   +30 more
wiley   +1 more source

Leveraging mRNA technology for antigen based immuno-oncology therapies. [PDF]

J Immunother Cancer
Floudas CS, Sarkizova S, Ceccarelli M, Zheng W.   +3 more
europepmc   +1 more source

Amino Acid Stress Response Genes Contribute to a 25‐Fold Increased Risk of L‐Asparaginase–Induced Hypersensitivity

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is essential in treating pediatric acute lymphoblastic leukemia (ALL) but is limited by hypersensitivity reactions in up to 70% of patients, leading to severe, dose‐limiting complications and compromised event‐free survival. Procedure This study conducted a genome‐wide association study (GWAS) in a discovery cohort of
Spencer J. Anderson, Erika N. Scott, Edward J. Raack, Wan‐Chun Chang, Miguel Córdova‐Delgado, Jessica N. Trueman, Catrina M. Loucks, S. Rod. Rassekh, Colin J. D. Ross, Bruce C. Carleton, the Canadian Pharmacogenomics Network for Drug Safety (CPNDS) consortium   +10 more
wiley   +1 more source

Multi-targeted, NOT gated CAR-T cells as a strategy to protect normal lineages for blood cancer therapy. [PDF]

Front Immunol
DiAndreth B, Nesterenko PA, Winters AG, Flynn AD, Jette CA, Suryawanshi V, Shafaattalab S, Martire S, Daris M, Moore E, Elshimali R, Gill T, Riley TP, Miller S, Netirojjanakul C, Hamburger AE, Kamb A.   +16 more
europepmc   +1 more source

EXPRESSION OF HLA-DR ANTIGENS ON PERIPHERAL BLOOD T LYMPHOCYTES AND RENAL GRAFT TUBULAR EPITHELIAL CELLS IN ASSOCIATION WITH REJECION

, 1986
Felix C. Henny, Jan J. Weening, William M. Baldwin, P. J. Oljans, Hans J. Tanke, Leendert A. van Es, Leendert C. Paul   +6 more
openalex   +1 more source

Soluble Thrombomodulin Is Associated With Endothelial Dysfunction Syndromes After Pediatric Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (HSCT) is challenged by endothelial dysfunction‐related syndromes like sinusoidal obstruction syndrome (SOS), capillary leak syndrome (CLS), and severe acute graft‐versus‐host disease (aGvHD). We investigated soluble thrombomodulin (sTM), an endothelial damage marker, in relation to
Denise Elbæk Horan, Pär I. Johansson, Marianne Ifversen, Claus H. Nielsen, Klaus Müller, Katrine Kielsen   +5 more
wiley   +1 more source