Results 21 to 30 of about 1,234,411 (332)

Measles virus epitope presentation by HLA: novel insights into epitope selection, dominance and microvariation

Frontiers in Immunology, 2015
Immunity to infections with Measles Virus (MV) can involve vigorous HLA class I restricted CD8+ cytotoxic T cell (CTL) responses. MV, albeit regarded monotypic, is known to undergo molecular evolution across its RNA genome.
Ingrid eSchellens, Ingrid eSchellens, Ingrid eSchellens, Hugo D Meiring, Ilka eHoof, Sanne eSpijkers, Sanne eSpijkers, Sanne eSpijkers, Martien C.M. Poelen, Jacqueline A.M. van Gaans-van den Brink, Ana I Costa, Ana I Costa, Harry eVennema, Can eKesmir, Debbie eVan Baarle, Debbie eVan Baarle, Debbie eVan Baarle, Cecile A.C.M. Van Els   +17 more
doaj   +1 more source

Intracellular class II HLA antigens are accessible to transferrin-neuraminidase conjugates internalized by receptor-mediated endocytosis.

Proceedings of the National Academy of Sciences of the United States of America, 1985
Newly synthesized class II HLA antigens being transported to the surface of human B-lymphoblastoid cell lines (B-LCL) interact with transferrin-neuraminidase conjugates internalized by means of receptor-mediated endocytosis.
P. Cresswell
semanticscholar   +1 more source

Influence of DM-sensitivity on immunogenicity of MHC class II restricted antigens

Journal for ImmunoTherapy of Cancer, 2021
Background Graft-versus-host-disease (GvHD) is a major problem in allogeneic stem cell transplantation. We previously described two types of endogenous human leukocyte antigen (HLA)-II restricted antigens depending on their behavior towards HLA-DM. While
Andreas Mackensen, Hannah Reimann, Edith D van der Meijden, Judith Bausenwein, Sascha Kretschmann, Anna Luise Bernhardt, Julia Zeun, Miriam Marecek, Margarete M Karg, Tabea Haug, Lisa Meintker, Gloria Lutzny-Geier, Anita N Kremer   +12 more
doaj   +1 more source

HLA antigens in malignant melanoma [PDF]

Cancer, 1977
HLA-A, -B, -C and -D typing was performed on 54 Norwegian patients with microscopically verified malignant melanoma. A slight, but non-significant increase in the frequency of HLA-B27 and LD 108 was demonstrated among the patients compared with healthy Norwegian controls.
O. Klepp, I. Brennhovd, B. O. Bergholtz, Erik Thorsby, Kaakinen A   +4 more
openaire   +4 more sources

Is There any Greater Possibility in Finding HLA-identical Unrelated Hematopoietic Stem Cell Donors among Thalassemia Families for Transplantation of Thalassemia Patients? [PDF]

International Journal of Hematology-Oncology and Stem Cell Research, 2004
Background: Thalassemia is probably the most common single gene disorder causing a major public health problem in the world. Currently, allogenic hematopoietic stem cell transplantation (HSCT) is the only curative therapy for thalassemia.
M Mohyeddin, P Alijanipour, K Alimoghaddam, A Ghavamzadeh, F Khosravi, B Nikbin   +5 more
doaj   +1 more source

EVALUATION OF HUMAN LEUKOCYTE ANTIGEN CLASS I AND II ANTIGENS IN HELICOBACTER PYLORI-POSITIVE PEDIATRIC PATIENTS WITH ACTIVE GASTRITIS AND DUODENAL ULCER

Arquivos de Gastroenterologia, 2017
BACKGROUND: As being the first bacteria determined to be carcinogenic, Helicobacter pylori (H. pylori) is a pathogen localized in the stomach in more than half of the world population.
Sevim GÖNEN, Sinan SARI, Yaşar KANDUR, Buket DALGIÇ, Oğuz SÖYLEMEZOĞLU   +4 more
doaj   +1 more source

Development and Validation of a Multiplex Non-HLA Antibody Assay for the Screening of Kidney Transplant Recipients

Frontiers in Immunology, 2018
The best treatment for patients with end-stage renal disease is kidney transplantation. Although graft survival rates have improved in the last decades, patients still may lose their grafts partly due to the detrimental effects of donor-specific ...
Elena G. Kamburova, Tineke Kardol-Hoefnagel, Bram W. Wisse, Irma Joosten, Wil A. Allebes, Arnold van der Meer, Luuk B. Hilbrands, Marije C. Baas, Eric Spierings, Cornelis E. Hack, Franka E. van Reekum, Arjan D. van Zuilen, Marianne C. Verhaar, Michiel L. Bots, Adriaan C. A. D. Drop, Loes Plaisier, Jan Meeldijk, Niels Bovenschen, Niels Bovenschen, Marc A. J. Seelen, Jan Stephan Sanders, Bouke G. Hepkema, Annechien J. A. Lambeck, Laura B. Bungener, Caroline Roozendaal, Marcel G. J. Tilanus, Christina E. Voorter, Lotte Wieten, Elly M. van Duijnhoven, Mariëlle A. C. J. Gelens, Maarten H. L. Christiaans, Frans J. van Ittersum, Shaikh A. Nurmohamed, Neubury M. Lardy, Wendy Swelsen, Karlijn A. M. I. van der Pant, Neelke C. van der Weerd, Ineke J. M. ten Berge, Frederike J. Bemelman, Paul J. M. van der Boog, Johan W. de Fijter, Michiel G. H. Betjes, Sebastiaan Heidt, Dave L. Roelen, Frans H. Claas, Henny G. Otten   +45 more
doaj   +1 more source

Keratinocyte differentiation antigen-specific T cells in immune checkpoint inhibitor-treated NSCLC patients are associated with improved survival

OncoImmunology, 2021
Immune checkpoint inhibitors (ICIs) have improved the survival of patients with non-small cell lung cancer (NSCLC) by reinvigorating tumor-specific T cell responses.
Fiamma Berner, Rebekka Niederer, Jolien J. Luimstra, Oltin Tiberiu Pop, Ann-Kristin Jochum, Mette-Triin Purde, Omar Hasan Ali, David Bomze, Jens Bauer, Lena Katharina Freudenmann, Ana Marcu, Eva-Maria Wolfschmitt, Sebastian Haen, Thorben Gross, Marissa Lisa Dubbelaar, Marie-Therese Abdou, Petra Baumgaertner, Christina Appenzeller, Caroline Cicin-Sain, Tobias Lenz, Daniel E. Speiser, Burkhard Ludewig, Christoph Driessen, Markus Jörger, Martin Früh, Wolfram Jochum, Antonio Cozzio, Hans-Georg Rammensee, Juliane Walz, Jacques Neefjes, Lukas Flatz   +30 more
doaj   +1 more source

Immunohistochemical identification of macrophages, lymphoid cells and HLA antigens in the human testis.

International Journal of Andrology, 1987
The presence and distribution of macrophages, several subtypes of lymphocytes and HLA antigens in the human testis were studied using monoclonal antibodies and immunocytochemical staining.
P. Pöllänen, M. Niemi
semanticscholar   +1 more source

Human Leukocyte Antigen Typing in Organ Transplantation: Methods, Clinical Relevance, and Practical Applications

Indian Journal of Kidney Diseases
Transplantation of tissues and organs is one of the greatest achievements of this century. Antigens which vary between members of same species are known as allo-antigens.
Shruti Tapiawala, Suchita Jogale
doaj   +1 more source