Results 31 to 40 of about 180,078 (140)

Human Leukocyte Antigen Typing in Organ Transplantation: Methods, Clinical Relevance, and Practical Applications

open access: yesIndian Journal of Kidney Diseases
Transplantation of tissues and organs is one of the greatest achievements of this century. Antigens which vary between members of same species are known as allo-antigens.
Shruti Tapiawala, Suchita Jogale
doaj   +1 more source

On the association between HLA-A1 and B5 and clinical forms of schistosomiasis mansoni

open access: yesMemorias do Instituto Oswaldo Cruz, 1991
The association between both HLA-A1 and B5 antigens and chronic forms of human schistosomiasis was studied in 64 patients and 26 normal controls from a southern Brazilian hospital.
P. H. Cabello   +3 more
doaj   +1 more source

Association of Alport's syndrome with HLA-DR2 antigen in a group of unrelated patients

open access: yesBrazilian Journal of Medical and Biological Research, 1998
A few family studies have evaluated HLA antigens in Alport's syndrome; however, there are no large population studies. In the present report, we studied 40 unrelated white patients with Alport's syndrome seen at the Unit of Renal Transplantation, Faculty
E.A. Donadi   +4 more
doaj   +1 more source

Trypanosoma cruzi vaccine candidate antigens Tc24 and TSA-1 recall memory immune response associated with HLA-A and -B supertypes in Chagasic chronic patients from Mexico. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2018
Trypanosoma cruzi antigens TSA-1 and Tc24 have shown promise as vaccine candidates in animal studies. We evaluated here the recall immune response these antigens induce in Chagasic patients, as a first step to test their immunogenicity in humans.
Liliana E Villanueva-Lizama   +11 more
doaj   +1 more source

Cancer vaccines: uses of HLA transgenic mice compared to genetically modified mice [PDF]

open access: yes, 2008
Many tumor antigens have been identified that can be targeted by the immune system. Animal models that have been genetically modified to express human HLA molecules instead of their own MHC antigens have shown to be valuable in the discovery of peptides ...
McArdle, SE
core  

Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma [PDF]

open access: yes, 2016
Immunotherapy approaches for pancreatic ductal adenocarcinoma (PDAC) have met with limited success. It has been postulated that a low mutation load may lead to a paucity of T cells within the tumor microenvironment (TME).
Alvarez, Hector A.   +13 more
core   +1 more source

Factors influencing transfusion-associated HLA sensitization in patients bridged to heart transplantation using ventricular assist device. [PDF]

open access: yes, 2020
BackgroundBridging heart failure patients with mechanical ventricular assist devices (VAD) enables access to transplantation. However, VAD is associated with increased risk for anti-HLA antibodies associated with rejection of subsequent allografts ...
Adler, Eric   +5 more
core   +1 more source

Escape from immunotherapy: possible mechanisms that influence tumor regression/progression [PDF]

open access: yes, 2004
Tumor escape is one major obstacle that has to be addressed prior to designing and delivering successful immunotherapy. There is compelling evidence to support the notion that immunogenic tumors, in murine models and cancer patients, can be rejected by ...
Ahmad, M, Ali, SA, Rees, RC
core   +1 more source

FREQUENCY OF OCCURRENCE OF ANTIBODIES TO HLA ANTIGENS IN RECIPIENTS ON THE WAITING LIST FOR KIDNEY TRANSPLANTATION

open access: yesМедицина в Кузбассе, 2023
Antibodies (a/t) to antigens (a/g) of human tissue compatibility HLA (human leucocyte antigens) are the main cause of kidney transplant rejection. Antigens of the HLAI class system (loci A, B, C) are present on all nucleated cells of the body, HLA class
Елена Борисовна Лукоянычева   +7 more
doaj  

VASCULAR ENDOTHELIAL GROWTH FACTOR AND HLA-PHENOTYPE IN PATIENTS WITH CHRONIC GLOMERULONEPHRITIS

open access: yesУкраїнський Журнал Нефрології та Діалізу, 2016
It was to determine associations the serum levels ofVEGF and with HLA inpatients with chronic glomerulonephritis and nephrotic syndrome (CGN, NS). Materials and methods.
М. Kolesnyk   +6 more
doaj   +1 more source

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