Results 71 to 80 of about 1,234,411 (332)

Identification of Two Novel HLA-A∗0201-Restricted CTL Epitopes Derived from MAGE-A4

Clinical and Developmental Immunology, 2010
MAGE-A antigens belong to cancer/testis (CT) antigens that are expressed in tumors but not in normal tissues except testis and placenta. MAGE-A antigens and their epitope peptides have been used in tumor immunotherapy trials.
Zheng-Cai Jia, Bing Ni, Ze-Min Huang, Yi Tian, Jun Tang, Jing-Xue Wang, Xiao-Lan Fu, Yu-Zhang Wu   +7 more
doaj   +1 more source

Single‐Cell and Spatial Transcriptomic Profiling of Penile Squamous Cell Carcinoma Reveals Dynamics of Tumor Differentiation and Immune Microenvironment

Advanced Science, EarlyView.
This study uses single‐nucleus RNA sequencing and spatial transcriptomics to investigate penile squamous cell carcinoma (PSCC). It reveals that PSCC tumor cells mimic normal penile epithelium differentiation, independent of HPV status. The Tum_1 subtype shows basal stem‐like characteristics and promotes invasiveness. HPV‐positive basal stem‐like tumors
Hongjian Song, Zhichao Tong, Guixiang Xie, Yaowei Li, Yubo Zhao, Fengpu Fan, Zongzheng Yang, Qing Shi, Qian Zhang, Feng Wen, Hongxue Meng, Haonan Li, Pengyu Guo, Dayong Hou, Zhenwei Zhang, Zhihao Yin, Ziyi Liu, Jianwei Wang, Peng Zhang, Peng Dai, Changfu Li, Lichen Teng, Yangyang Xu, Dexin Ding, Tao Xu, Jianzhang Li, Yongsheng Chen, Yu Qiu, XiaoWei Hu, Wentao Liu, Liang Wu, Roman Nawroth, Guibo Li, Hang Su, Ziqing Deng, Ziqi Wang, Di Wang, Wanhai Xu   +37 more
wiley   +1 more source

HLA profile in patients with AIDS and tuberculosis

Brazilian Journal of Infectious Diseases
Studies carried out in various populations have reported an association between some HLA specificities and susceptibility to tuberculosis. We investigated the class I and class II HLA profile in Brazilian patients of various ethnic backgrounds who had ...
José Fernando de Castro Figueiredo, Maria de Lourdes Veronese Rodrigues, Neifi Hassam Saloum Deghaide, Eduardo Antonio Donadi   +3 more
doaj   +1 more source

3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene Signatures

Advanced Science, EarlyView.
This study developed a 3D brain vascular niche model that capture the key features of glioblastoma including perivascular infiltration, gene signature, dormancy and chemo resistance, by comparing 3D model with in vivo condition using identical glioma stem cells.
Vivian K. Lee, Rut Tejero, Nathaniel Silvia, Anirudh Sattiraju, Aarthi Ramakrishnan, Li Shen, Alexandre Wojcinski, Santosh Kesari, Roland H. Friedel, Hongyan Zou, Guohao Dai   +10 more
wiley   +1 more source

Identification of HLA Class I Misreads/Dropouts Using Serological Typing, in Comparison with DNA-based Typing

Iranian Journal of Allergy, Asthma and Immunology, 2016
Serology and DNA techniques are employed for Human Leukocyte Antigen (HLA) typing in different transplant centers. Results may not always correlate well and may need retyping with different technique.
Hamid Nawaz Tipu, Muhammad Mukarram Bashir, Muhammad Noman   +2 more
doaj  

The Dual Role of HLA-C in Tolerance and Immunity at the Maternal-Fetal Interface

Frontiers in Immunology, 2019
To establish a healthy pregnancy, maternal immune cells must tolerate fetal allo-antigens and remain competent to respond to infections both systemically and in placental tissues.
Henrieta Papúchová, Torsten B. Meissner, Torsten B. Meissner, Qin Li, Jack L. Strominger, Tamara Tilburgs, Tamara Tilburgs   +6 more
doaj   +1 more source

The role of HLA antigens in recurrent primary focal segmental glomerulosclerosis. [PDF]

Front Immunol, 2023
Batal I, Khairallah P, Weins A, Andeen NK, Stokes MB.   +4 more
europepmc   +1 more source

Paracrine Orchestration of Tumor Microenvironment Remodeling Induced by GLO1 Potentiates Lymph Node Metastasis in Breast Cancer

Advanced Science, EarlyView.
Single‐cell RNA sequencing of lymph node (LN) samples is performed, and a comprehensive landscape of the entire ecosystem is generated. Paracrine orchestration of TME remodeling induced by GLO1 potentiates LN metastasis in breast cancer. This study offers novel perspectives on the microenvironment remodeling of breast cancer LN metastases, suggesting ...
Jindong Xie, Wenjian Liu, Xinpei Deng, Huan Wang, Xueqi Ou, Xin An, Min‐Yi Situ, Anli Yang, Chuan Peng, Rongfang He, Yi Xie, Hailin Tang, Yuman Chen, Jie‐Ying Liang, Ruonan Shao, Weikai Xiao, Shaoquan Zheng   +16 more
wiley   +1 more source

Genetic marker in juvenile diabetic retinopathy

Indian Journal of Ophthalmology, 1989
Thirty five patients with insulin dependent diabetes mellitus (IDDM) were investigated for development of retinal microangiopathy by fluorescein angiography. HLA typing (A,B.C antigens) was done as a genetic marker. There was no statistically significant
Khosla P, Sharma K, Tiwari H, Bajaj J, Vaidya M   +4 more
doaj  

A Case Report of Aggressive Fumarate Hydrase-deficient Renal Cell Carcinoma With Loss of HLA Antigens. [PDF]

Cancer Diagn Progn, 2023
Miura Y, Motoshima T, Anami T, Takemura K, Kinowaki K, Oka S, Urakami S, Kamba T, Komohara Y.   +8 more
europepmc   +1 more source